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Ribonucleoside Diphosphate Reductase

An enzyme of the oxidoreductase class that catalyzes the formation of 2'-deoxyribonucleotides from the corresponding ribonucleotides using NADPH as the ultimate electron donor. The deoxyribonucleoside diphosphates are used in DNA synthesis. (From Dorland, 27th ed) EC 1.17.4.1.
Also Known As:
UDP Reductase; Diphosphate Reductase, Ribonucleoside; Reductase, Ribonucleoside Diphosphate; Reductase, UDP; 2'-Deoxyribonucleoside-diphosphate:oxidized-thioredoxin 2'-oxidoreductase
Networked: 26 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Ge, Fei-Jiao: 1 article (01/2016)
2. Jia, R U: 1 article (01/2016)
3. Lin, L I: 1 article (01/2016)
4. Liu, Rong-Rui: 1 article (01/2016)
5. Qin, Quan-Hong: 1 article (01/2016)
6. Stojsic, Jelena: 1 article (01/2016)
7. Wang, Yan: 1 article (01/2016)
8. Xu, Chun-Wei: 1 article (01/2016)
9. Xu, Jian-Ming: 1 article (01/2016)
10. Zhang, B O: 1 article (01/2016)

Related Diseases

1. Infections
2. Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
3. Esophageal Squamous Cell Carcinoma
4. Neoplasms (Cancer)
5. Hepatocellular Carcinoma (Hepatoma)

Related Drugs and Biologics

1. Tubulin
2. Proteins (Proteins, Gene)
3. Thymidylate Synthase
4. Ligases (Synthetase)
5. Endonucleases
6. Survivin
7. triphosphoric acid (triphosphate)
8. Hydroxyurea (Hydrea)
9. Enzymes
10. DNA (Deoxyribonucleic Acid)

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Immunotherapy