Rhinosporidiosis

Chronic, localized granulomatous infection of mucocutaneous tissues, especially the NOSE, and characterized by HYPERPLASIA and the development of POLYPS. It is found in humans and other animals and is caused by the mesomycetozoean organism RHINOSPORIDIUM SEEBERI.

Also Known As:

Networked: 33 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Infection
2.	Polyps
3.	Inverted Papilloma
4.	Chalazion
5.	Nasal Obstruction

Experts

1.	Arseculeratne, S N: 5 articles (10/2011 - 07/2002)
2.	Eriyagama, N B: 3 articles (10/2011 - 01/2005)
3.	Atapattu, D N: 2 articles (04/2006 - 01/2005)
4.	Prasad, Vishnu: 1 article (05/2015)
5.	Shenoy, Vijendra S: 1 article (05/2015)
6.	Rao, Kanishka S: 1 article (05/2015)
7.	Kamath, Panduranga M: 1 article (05/2015)
8.	Rao, Raghavendra A: 1 article (05/2015)
9.	Bialek, Ralf: 1 article (01/2015)
10.	Haeupler, Alexandra: 1 article (01/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Rhinosporidiosis:

1.	DapsoneFDA Link 01/01/2014 - "Comments on 'novel multidrug therapy for disseminated rhinosporidiosis, refractory to dapsone - case report'." 07/01/2013 - "Novel multidrug therapy for disseminated rhinosporidiosis, refractory to dapsone – case report." 05/01/2011 - "Disseminated cutaneous with nasopharyngeal rhinosporidiosis: Light microscopy changes following dapsone therapy." 12/01/1997 - "Morphological findings in serial nasal mucosal biopsies from three cases of rhinosporidiosis on dapsone therapy were compared with biopsies from 33 patients taken before dapsone or surgical treatment was initiated. " 12/01/1997 - "Light and electron microscopic findings in rhinosporidiosis after dapsone therapy."
2.	AntigensIBA 09/01/1982 - "Detection of circulating antigen in patients with rhinosporidiosis." 09/01/1982 - "A study was undertaken to demonstrate antibodies or antigen in the serum or plasma of 69 patients with rhinosporidiosis. "
3.	AntibodiesIBA 09/01/1982 - "A study was undertaken to demonstrate antibodies or antigen in the serum or plasma of 69 patients with rhinosporidiosis. "
4.	Amphotericin B (Amphotericin)FDA LinkGeneric 06/01/2007 - "Second case presented with recurrence of rhinosporidiosis even after nine times surgical intervention with systemic Amphotericin-B. " 01/01/1986 - "This paper reports a case of rhinosporidiosis which presented with widespread subcutaneous nodular lesions which failed to respond to surgical excision or to intravenous amphotericin B. "
5.	tebufenozide (Mimic)IBA 01/01/2011 - "Nasal rhinosporidioss lesions may largely mimic other ordinary nasal polyps, it is crucial therefore for clinicians in our region to consider rhinosporidiosis as a differential diagnosis when assessing patients presenting with nasal swellings." 01/01/2012 - "Rhinosporidiosis may mimic a burst chalazion or a simple conjunctival polyp. "
6.	Tuberculin (PPD)IBA 01/01/2010 - "Mantoux positivity to PPD was found in 65% of normal Sri Lankans, by only 35% of patients with rhinosporidiosis. "
7.	Silver NitrateIBA 04/01/2006 - "Anti-rhinosporidial antiseptics that could be used in surgery on rhinosporidial patients include povidone-iodine in nasal packs for nasal and naso-pharyngeal surgery, chlorhexidine and cetrimide-chlorhexidine on the skin, while povidone-iodine and silver nitrate could have application in ocular rhinosporidiosis."
8.	28S Ribosomal RNAIBA 01/01/2015 - "Five different previously described panfungal PCR/sequencing protocols targeting 18S and 28S ribosomal RNA gene fragments as well as internal transcribed spacer 1 and 2 fragments were evaluated with a collection of 17 formalin-fixed, paraffin-embedded tissue samples of patients with rare and/or tropical invasive mycoses, comprising chromoblastomycosis, coccidioidomycosis, cryptococcosis, histoplasmosis, mucormycosis, mycetoma/maduromycosis, and rhinosporidiosis, in a proof-of-principle analysis. "
9.	Povidone-Iodine (Betadine)FDA LinkGeneric 04/01/2006 - "Anti-rhinosporidial antiseptics that could be used in surgery on rhinosporidial patients include povidone-iodine in nasal packs for nasal and naso-pharyngeal surgery, chlorhexidine and cetrimide-chlorhexidine on the skin, while povidone-iodine and silver nitrate could have application in ocular rhinosporidiosis."
10.	ParaffinIBA 01/01/2015 - "Five different previously described panfungal PCR/sequencing protocols targeting 18S and 28S ribosomal RNA gene fragments as well as internal transcribed spacer 1 and 2 fragments were evaluated with a collection of 17 formalin-fixed, paraffin-embedded tissue samples of patients with rare and/or tropical invasive mycoses, comprising chromoblastomycosis, coccidioidomycosis, cryptococcosis, histoplasmosis, mucormycosis, mycetoma/maduromycosis, and rhinosporidiosis, in a proof-of-principle analysis. "

Therapies and Procedures

1.	Transplants (Transplant) 05/01/2011 - "Tectonic corneal graft for conjunctival rhinosporidiosis with scleral melt." 10/01/1990 - "A remarkable case of a scleral melting reaction in association with conjunctival rhinosporidiosis is presented and its surgical treatment with a scleral graft described."
2.	Diathermy 01/01/2005 - "The average age is 34 years (range: 16 to 60 years); old nasal obstruction is the main symptom (12 cases); the diagnosis is histologic; association with Killian polyp (1 case), human papilloma virus infection (1 case) and rhinosporidiosis (1 case); large surgical removal (Caldwell-Luc, para-latero-nasal) and polypectomy associated to diathermy of tumorous insertion place permitted to have satisfactory results; the recurrencies were observed in four cases from 7 months to 10 years (average: 4 years); malignant transformation is noted in 2 cases with one case of inverted papilloma combined to Human Papilloma Virus infection. " 05/01/2015 - "We report a case of Rhinosporidiosis at the lateral pharyngeal wall which is a very rare site for Rhinosporidiosis to occur; was treated by diathermy excision of the mass and cauterization of the base and oral Dapsone to prevent recurrence of the disease. "
3.	Laryngoscopes 03/01/2012 - "Orotracheal intubation facilitated with a GlideScope GVL® video laryngoscope in a patient with a large oronasopharyngeal rhinosporidiosis."
4.	Bronchoscopes 04/01/2010 - "In this case report, we highlight our technique in the management of the airway in a case of laryngeal rhinosporidiosis using a combination of fiberoptic bronchoscope and an endoscope. "
5.	Endoscopes 04/01/2010 - "In this case report, we highlight our technique in the management of the airway in a case of laryngeal rhinosporidiosis using a combination of fiberoptic bronchoscope and an endoscope. "