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Cumulative Trauma Disorders (Repetitive Strain Injury)

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Harmful and painful condition caused by overuse or overexertion of some part of the musculoskeletal system, often resulting from work-related physical activities. It is characterized by inflammation, pain, or dysfunction of the involved joints, bones, ligaments, and nerves.

Also Known As:

Repetitive Strain Injury; Overuse Injuries; Overuse Syndrome; Disorders, Repetitive Motion; Repetitive Motion Disorder; Injury, Repetition Strain; Overuse Injury; Repetitive Motion Disorders; Strain Injury, Repetition; Cumulative Trauma Disorder; Disorder, Cumulative Trauma; Disorder, Repetitive Motion; Disorders, Cumulative Trauma; Injuries, Overuse; Injuries, Repetition Strain; Injuries, Repetitive Strain; Injury, Overuse; Injury, Repetitive Strain; Motion Disorder, Repetitive; Motion Disorders, Repetitive; Overuse Syndromes; Repetition Strain Injuries; Repetitive Strain Injuries; Strain Injuries, Repetition; Strain Injuries, Repetitive; Strain Injury, Repetitive; Trauma Disorder, Cumulative; Repetition Strain Injury; Trauma Disorders, Cumulative

Networked: 130 relevant articles (3 outcomes, 24 trials/studies)

Relationship Network

Disease Context: Research Results

Wounds and Injuries: 94065
- Sprains and Strains: 459
  - Cumulative Trauma Disorders: 130

Related Diseases

1.	Pain (Aches)
2.	Stress Fractures (Stress Fracture)
3.	Carpal Tunnel Syndrome
4.	Reflex Sympathetic Dystrophy (Reflex Sympathetic Dystrophy Syndrome)
5.	Wounds and Injuries (Trauma)

Experts

1.	Barbe, Mary F: 2 articles (03/2015 - 03/2010)
2.	Litvin, Judith: 2 articles (03/2015 - 03/2010)
3.	Landorf, Karl B: 2 articles (01/2015 - 01/2011)
4.	Moran, Daniel S: 2 articles (07/2013 - 11/2008)
5.	van Tulder, M W: 2 articles (10/2001 - 10/2000)
6.	Pujol, N: 1 article (12/2015)
7.	Lutz, C: 1 article (12/2015)
8.	Le Henaff, G: 1 article (12/2015)
9.	Potel, J-F: 1 article (12/2015)
10.	Seil, R: 1 article (12/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Cumulative Trauma Disorders:

1.	beta-cyclodextrin tetradecasulfate (CTDS)IBA 01/01/2012 - "This study examines changes in body temperature generated in the wrist area through sensory thermography technique because of highly repetitive movements, proving with this technique that there is a decreased ability to perform muscular work, and thereby assess possible pathologies of Cumulative Trauma Disorders (CTDs). " 01/01/2008 - "The objectives of this study were to investigate the rate of cumulative trauma disorders (CTDs) in the upper body and to describe the associations of such disorders with ergonomic parameters in a group of data entry operators. " 10/14/2004 - "Cumulative trauma disorders (CTDs) are common in musicians and their prevalence has been the subject of a number of studies in most western countries. " 02/01/1998 - "This study was motivated by the serious impact that cumulative trauma disorders (CTDs) of the upper extremities have on the meat packing industry. " 01/01/1997 - "This study examined the prevalence of cumulative trauma disorders (CTDs) among hand therapists. "
2.	IronIBA 09/01/2013 - "High prevalence of overuse injury among iron-distance triathletes." 11/01/2008 - "Previous studies on females in combat training have found a high prevalence of iron deficiency at recruitment as well as an increased rate of stress fractures (SF) and overuse injuries during training when compared with males. "
3.	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 05/01/2008 - "Growth factors mediate the biological processes necessary for repair of soft tissues such as muscle, tendon and ligament following acute traumatic or overuse injury, and animal studies have demonstrated clear benefits in terms of accelerated healing. "
4.	HydrogelsIBA 03/01/2011 - "PEG-based hydrogels with tunable degradation characteristics to control delivery of marrow stromal cells for tendon overuse injuries." 03/01/2011 - "In this study novel degradable hydrogels based on oligo(poly(ethylene glycol) fumarate) (OPF) and acrylated poly(ethylene glycol)-dithiothreitol (Ac PEG-DTT) with tunable degradation times ranging from a few days to >1 month were synthesized as MSC carriers for tendon overuse injuries. "
5.	Ethylene Glycol (Monoethylene Glycol)IBA 03/01/2011 - "In this study novel degradable hydrogels based on oligo(poly(ethylene glycol) fumarate) (OPF) and acrylated poly(ethylene glycol)-dithiothreitol (Ac PEG-DTT) with tunable degradation times ranging from a few days to >1 month were synthesized as MSC carriers for tendon overuse injuries. "
6.	Indomethacin (Indometacin)FDA LinkGeneric 10/01/1990 - "In this double-blind trial in 70 athletes with superficial overuse injuries, the effect of topically and systemically administered indomethacin was compared with a placebo control. " 10/01/1990 - "The results on efficacy as well as adverse reactions favour the use of topical indomethacin in superficial overuse injuries in athletes." 10/01/1990 - "Topical indomethacin in overuse injuries in athletes. "
7.	Dithiothreitol (Cleland's Reagent)IBA 03/01/2011 - "In this study novel degradable hydrogels based on oligo(poly(ethylene glycol) fumarate) (OPF) and acrylated poly(ethylene glycol)-dithiothreitol (Ac PEG-DTT) with tunable degradation times ranging from a few days to >1 month were synthesized as MSC carriers for tendon overuse injuries. "
8.	oligo(poly(ethylene glycol)fumarate)IBA 03/01/2011 - "In this study novel degradable hydrogels based on oligo(poly(ethylene glycol) fumarate) (OPF) and acrylated poly(ethylene glycol)-dithiothreitol (Ac PEG-DTT) with tunable degradation times ranging from a few days to >1 month were synthesized as MSC carriers for tendon overuse injuries. "
9.	IceIBA 03/01/2015 - " project a competition program as much as possible safe regarding overuse injury prevention an accurate knowledge of physiological parameters of the ice dancer and of ISU rules is necessary. " 07/01/2003 - "Pairs skaters and ice dance skaters had a higher risk of acute injury than overuse syndrome because of falls from lifts and throw jumps. " 12/01/1998 - "Intense training leads therefore to specific sports injuries and chromic overuse injuries of the ice skaters. " 11/01/1990 - "Overuse syndromes mandate rest and control of inflammation through the use of ice, NSAIDs, and local injections of steroids followed by passive, active-assist, and active ROM; stretching; and mobilization exercises. "
10.	PlasticsIBA 06/01/2001 - "These plastic changes are fundamental to the accomplishment of skillful playing, but they pose a risk for the development of motor control dysfunctions that may give rise to overuse syndromes and focal, task-specific dystonia." 12/01/1994 - "Not only can the risk of lower back injuries be decreased by using plastic bags with handles but the risk of developing a cumulative trauma disorder could also be decreased." 10/23/1999 - "Phantom-limb sensation, and repetitive strain injuries or focal hand dystonias in writers, musicians, or keyboard operators, are accompanied by plastic changes in sensorimotor cortex and by pathological pain. "

Therapies and Procedures

1.	Orthotic Devices (Orthosis) 09/01/1994 - "While it is documented that many overuse injuries of the lower limb can be relieved with the use of biomechanical foot orthoses, what remains unclear is how an orthosis can produce this effect. " 01/01/2015 - "This randomised controlled trial will evaluate the effectiveness of prefabricated foot orthoses for the prevention of common lower limb overuse injuries in naval recruits. " 01/01/2015 - "The primary aim of this study is to determine if prefabricated foot orthoses reduce the incidence of lower limb overuse injuries in naval recruits undertaking 11 weeks of basic training. " 01/01/2015 - "Foot orthoses for the prevention of lower limb overuse injuries in naval recruits: study protocol for a randomised controlled trial." 09/01/2011 - "Clinical effectiveness of customised sport shoe orthoses for overuse injuries in runners: a randomised controlled study."
2.	Psychology Biofeedback (Biofeedback) 11/01/1995 - "This study examined the relative effectiveness of EMG biofeedback, applied relaxation training and a combined procedure in the management of chronic, upper extremity cumulative trauma disorder. " 11/01/1995 - "Effect of EMG biofeedback compared to applied relaxation training with chronic, upper extremity cumulative trauma disorders." 01/01/1994 - "Electromyographic biofeedback evaluation of a computer keyboard operator with cumulative trauma disorder." 10/01/1996 - "The study examined the effectiveness of behaviorally-induced vasodilation (hypnosis with biofeedback and autogenics) in the treatment of upper extremity repetitive strain injuries (RSI). "
3.	Spinal Manipulation 05/01/2010 - "These findings may help to clarify the mechanisms responsible for the effective relief of pain and restoration of functional ability documented after spinal manipulation and the mechanism involved in the initiation of overuse injuries."
4.	Sign Language 03/01/1993 - "Electromyographic study of overuse syndromes in sign language interpreters." 07/01/1992 - "This report provides a general summary of selected findings as well as a conceptual framework that should help clarify the factors associated with upper extremity cumulative trauma disorders in sign language interpreters. " 07/01/1992 - "Upper extremity cumulative trauma disorders became a potentially significant occupational hazard among sign language interpreters at the National Technical Institute for the Deaf in the 1988-89 academic year. " 03/01/1992 - "Symptoms associated with upper extremity cumulative trauma disorders (UECTDs) recently have been reported in professional sign language interpreters. " 03/01/1992 - "Biomechanical factors affecting upper extremity cumulative trauma disorders in sign language interpreters."
5.	Lasers (Laser) 02/01/2010 - "Analysis of the typical laser photocoagulation procedure revealed a high risk for cumulative trauma disorders. " 12/01/1993 - "Temperature and blood flow studies were performed in the upper limbs of six patients with reflex sympathetic dystrophy (RSD), nine patients with repetitive strain injury (RSI) and 12 control subjects using thermography, laser Doppler flowmetry, infrared photoplethysmography and venous occlusion strain gauge plethysmography. "