Reflex Sympathetic Dystrophy (Reflex Sympathetic Dystrophy Syndrome)

A syndrome characterized by severe burning pain in an extremity accompanied by sudomotor, vasomotor, and trophic changes in bone without an associated specific nerve injury. This condition is most often precipitated by trauma to soft tissue or nerve complexes. The skin over the affected region is usually erythematous and demonstrates hypersensitivity to tactile stimuli and erythema. (Adams et al., Principles of Neurology, 6th ed, p1360; Pain 1995 Oct;63(1):127-33)
Also Known As:
Reflex Sympathetic Dystrophy Syndrome; Syndrome, Reflex Sympathetic Dystrophy; Syndrome, Shoulder-Hand; Algodystrophic Syndrome; CPRS Type I; Cervical Sympathetic Dystrophy; Pain Syndrome Type I, Complex Regional; RSD (Reflex Sympathetic Dystrophy); Sudek's Atrophy; Sympathetic Reflex Dystrophia; Type I Complex Regional Pain Syndrome; Algodystrophies; Atrophies, Sudek's; Atrophy, Sudek; Atrophy, Sudek's; CPRS Type Is; Cervical Sympathetic Dystrophies; Dystrophies, Cervical Sympathetic; Dystrophies, Reflex Sympathetic; Dystrophy, Cervical Sympathetic; Dystrophy, Reflex Sympathetic; I, CPRS Type; Is, CPRS Type; RSDs (Reflex Sympathetic Dystrophy); Reflex Dystrophia, Sympathetic; Reflex Sympathetic Dystrophies; Shoulder Hand Syndrome; Shoulder-Hand Syndromes; Sudek's Atrophies; Sudeks Atrophy; Sympathetic Dystrophies, Cervical; Sympathetic Dystrophies, Reflex; Sympathetic Dystrophy, Cervical; Sympathetic Dystrophy, Reflex; Sympathetic Reflex Dystrophias; Syndrome, Algodystrophic; Syndromes, Shoulder-Hand; Type I, CPRS; Type Is, CPRS; Algodystrophy; Complex Regional Pain Syndrome, Type I; Pain Syndrome Type I, Regional, Complex; Shoulder-Hand Syndrome; Sudek Atrophy
Networked: 514 relevant articles (34 outcomes, 37 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Pain (Aches)
2. Hyperhidrosis
3. Causalgia (Syndrome, Causalgia)
4. Neoplasms (Cancer)
5. Ischemia


1. Adami, Silvano: 4 articles (07/2014 - 10/2009)
2. Kingery, Wade S: 4 articles (08/2009 - 03/2004)
3. Guo, Tian-Zhi: 4 articles (08/2009 - 03/2004)
4. Bodde, Marlies I: 3 articles (01/2014 - 10/2011)
5. Dijkstra, Pieter U: 3 articles (01/2014 - 10/2011)
6. Idolazzi, Luca: 3 articles (03/2013 - 10/2009)
7. Gatti, Davide: 3 articles (03/2013 - 10/2009)
8. Zhao, Rong: 3 articles (08/2009 - 08/2008)
9. Taira, T: 3 articles (01/2007 - 01/2003)
10. Hori, T: 3 articles (01/2007 - 01/2003)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Reflex Sympathetic Dystrophy:
1. GuanethidineFDA Link
2. pamidronate (APD)FDA LinkGeneric
3. Calcitonin (Calcitonin, Eel)FDA LinkGeneric
4. gabapentin (Neurontin)FDA LinkGeneric
5. Capsaicin (Zostrix)FDA Link
6. Reserpine (Serpasil)FDA Link
7. Dimethyl Sulfoxide (DMSO)FDA LinkGeneric
8. Clodronic Acid (Clodronate)IBA
9. salmon calcitonin (Calcimar)FDA LinkGeneric
10. OxygenIBA

Therapies and Procedures

1. Sympathectomy (Sympathectomies)
2. Electroacupuncture
3. Acupuncture Points (Acupuncture Point)
4. Acupuncture Therapy
5. Oral Administration