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Recombinant Proteins

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Proteins prepared by recombinant DNA technology.

Also Known As:

Proteins, Biosynthetic; Proteins, Recombinant DNA; DNA Proteins, Recombinant; Proteins, DNA Recombinant; Proteins, Recombinant; Recombinant DNA Proteins; Recombinant Proteins, DNA; Biosynthetic Proteins; DNA Recombinant Proteins

Networked: 747 relevant articles (31 outcomes, 74 trials/studies)

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Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins
- Proteins: 90489
  - Recombinant Proteins: 747

Experts

1.	Bannantine, John P: 6 articles (01/2015 - 01/2007)
2.	Hashimoto, T: 5 articles (07/2015 - 01/2001)
3.	Duthie, Malcolm S: 5 articles (08/2014 - 11/2008)
4.	Guzmán, María G: 5 articles (07/2014 - 01/2008)
5.	Guillén, Gerardo: 5 articles (07/2014 - 01/2008)
6.	Hermida, Lisset: 5 articles (07/2014 - 01/2008)
7.	Whittington, Richard J: 5 articles (06/2014 - 06/2009)
8.	Reed, Steven G: 5 articles (01/2011 - 03/2004)
9.	Deloron, Philippe: 4 articles (01/2015 - 04/2006)
10.	Spencer, John S: 4 articles (02/2011 - 09/2005)

Related Diseases

1.	Infection 10/01/2009 - "In five recombinant proteins, the recombinant proteins PL1, PL3 and PL4 as vaccine were able to elicit formation of the better protective effects on mice against infection of Fusobacterium necrophorum strain A25." 03/01/2010 - "We evaluated the potentials of the recombinant proteins for discriminating active from prior infections, as well as the therapeutic efficacy of the established ELISA technique." 09/24/1999 - "Therefore, the LUC activity measured during infection of such a bi-cistronic virus, permits an on-line estimation of the recombinant protein level, a very useful feature for large-scale production of recombinant proteins. " 12/09/2009 - "However, the study reveals some positive results on immune response and efficacy for both recombinant proteins; these results are being discussed in order to suggest new approaches with new chronic infection mouse models and adjuvants." 06/01/2007 - "The efficacy of vaccination against Haemonchus contortus infection with two recombinant proteins, rHco-gal-m and rHco-gal-f, was studied in 9-10-month-old goats. "
2.	Leishmaniasis 01/01/2013 - "Towards a more precise serological diagnosis of human tegumentary leishmaniasis using Leishmania recombinant proteins." 01/01/2012 - "Leishmania infantum) recombinant proteins, rLci2B and rLci1A, and their use in the development of an immunoassay for the diagnostic of canine leishmaniasis. " 01/01/2012 - "Evaluation of an ELISA for canine leishmaniasis immunodiagnostic using recombinant proteins." 01/01/2009 - "The characteristics and in vitro stimulating capability of the recombinant proteins expressed by previously identified clones on the basis of their capacity to stimulate an indigenously established Leishmania-specific cell line leading to high level of IFN-gamma suggested these to be potential candidates for immunoprophylaxis against leishmaniasis. " 01/01/2009 - "In this study, we investigated the protective efficacy of purified recombinant proteins from two of the identified cDNA clones along with the adjuvant MPL, in a hamster model of experimental leishmaniasis. "
3.	Parasitic Diseases (Parasitic Disease) 11/01/1997 - "For the serodiagnosis of this parasitic disease, two immunodominant clones from a bovine Neospora lambda gt11 library were identified, characterized, and expressed as recombinant proteins for the development of an enzyme-linked immunosorbent assay (ELISA). " 06/01/1993 - "Recombinant proteins have been proposed as subunit vaccines for many viral, bacterial and parasitic diseases, to reduce adverse side effects associated with inactivated or attenuated vaccines. " 01/01/2012 - "Furthermore, we show that naked DNA coupled with raw recombinant proteins produced in insect larvae biofactories -the cheapest way of producing DNA-PROT vaccines- is a practical and cost-effective way for potential "off the shelf" supplying vaccines at very low prices for the protection against leishmaniases, and possibly against other parasitic diseases affecting the poorest of the poor." 06/01/1995 - "In the quest for effective immunization against complex diseases such as cancer, parasitic diseases, AIDS, and other viral infections, numerous peptides and recombinant proteins have been synthesized, examined for the ability to induce antibodies and CTLs, and tested for binding capability and therapeutic or prophylactic efficacy against the original target cell or organism. "
4.	Neoplasms (Cancer) 05/11/2010 - "Stability studies were performed using recombinant proteins in surrogate matrices, endogenous analytes in healthy volunteer and cancer patient plasma. " 11/01/2009 - "For this purpose, the five cancer-associated BRCT mutants: V1696L, M1775K, M1783T, V1809F, and P1812A were cloned in suitable prokaryotic protein production vectors, and the recombinant proteins were purified in soluble and stable form for further biophysical studies. " 06/01/2015 - "The recombinant proteins that were produced with our purification strategy will be instrumental to perform a wide range of functional assays aimed at dissecting the molecular mechanisms of RNASET2-mediated tumor suppression. " 01/01/2015 - "Thus, the nanostructures investigated here offer an attractive alternative to the use of anti-angiogenic recombinant proteins in the treatment of cancer or other diseases involving abnormal blood vessel formation. " 12/01/2012 - "The integration-free ways, such as adenovirus, plasmid, recombinant proteins, and L-myc replacement used in iPS technology significantly reduce the risk of cancer. "
5.	Malaria 12/01/2002 - "In the present study we demonstrate that this combination of recombinant proteins dramatically enhances protection against lethal malaria challenge compared to either protein administered alone. " 07/01/2015 - "We determined naturally acquired antibody responses to the recombinant proteins Pfs48/45-10C and Pfs230-230CMB in children from three malaria endemic settings in Ghana, Tanzania and Burkina Faso. " 08/01/2011 - "In the frontline, adenoviruses and poxviruses seem to be giving the best immunization results in experimental animals and their mutual combination, or their combination with recombinant proteins (formulated in adjuvants and given in sequence or being given as protein/virus admixtures), has been shown to reach unprecedented levels of anti-malaria immunity that predictably will be somehow reproduced in the human setting. " 01/01/2008 - "Using recombinant proteins corresponding to five domains of the expressed A4 var gene, A4 PfEMP1, the naturally occurring antibody response was assessed, by ELISA, to each domain in serum samples obtained from individuals resident in two communities of differing malaria transmission intensity on the Kenyan coast. " 12/01/2007 - "We studied the molecular interaction of Fd and FNR of human malaria parasite (Plasmodium falciparum), which were produced as recombinant proteins in Escherichia coli. "

Related Drugs and Biologics

1.	Antigens
2.	Vaccines
3.	DNA (Deoxyribonucleic Acid)
4.	Antibodies
5.	Proteins (Proteins, Gene)
6.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
7.	Peptides
8.	Complementary DNA (cDNA)
9.	Peroxiredoxins
10.	nucleotidase

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Immunomodulation
3.	Therapeutics
4.	Immunotherapy
5.	Heterologous Transplantation (Xenotransplantation)