A class of histamine receptors discriminated by their pharmacology and mode of action. Most histamine H1 receptors operate through the inositol phosphate/diacylglycerol second messenger system. Among the many responses mediated by these receptors are smooth muscle contraction, increased vascular permeability, hormone release, and cerebral glyconeogenesis. (From Biochem Soc Trans 1992 Feb;20(1):122-5)
Also Known As:
Histamine H1 Receptor; Receptors, Histamine H1; H1 Receptors; Receptors, H1; H1 Receptor, Histamine; H1 Receptors, Histamine; Receptor, H1; Receptor, Histamine H1; H1 Receptor