Drug Receptors (Drug Receptor)

Proteins that bind specific drugs with high affinity and trigger intracellular changes influencing the behavior of cells. Drug receptors are generally thought to be receptors for some endogenous substance not otherwise specified.

Also Known As:

Networked: 41 relevant articles (5 outcomes, 5 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Ingelman-Sundberg, M: 2 articles (01/2008 - 09/2001)
2.	Wang, Wei: 1 article (01/2014)
3.	Gonzalez-Malerva, Laura: 1 article (01/2014)
4.	LaBaer, Joshua: 1 article (01/2014)
5.	Yu, Xiaobo: 1 article (01/2014)
6.	Bosch-Morell, Francisco: 1 article (01/2014)
7.	Mérida, Salvador: 1 article (01/2014)
8.	Navea, Amparo: 1 article (01/2014)
9.	Muriach, María: 1 article (01/2014)
10.	Yin, Linliang: 1 article (01/2014)

Related Diseases

1.	Drug Toxicity (Drug Safety) 03/01/2004 - "Ina similar manner, polymorphisms in the genes encoding drug metabolizing enzymes, drug transporters, and drug receptors can influence a neonate's risk of an adverse drug reaction or can alter the efficacy of drug treatment. " 01/01/2008 - "Pharmacogenetics encompasses genetic variation with importance for drug response and adverse drug reactions with emphasis on drug transporters, drug metabolizing enzymes, and drug receptors. " 11/11/2000 - "Polymorphisms in the genes that code for drug-metabolising enzymes, drug transporters, drug receptors, and ion channels can affect an individual's risk of having an adverse drug reaction, or can alter the efficacy of drug treatment in that individual. " 12/01/1998 - "Major research challenges include the following: (1) the genetic variation of drug targets (receptors, enzymes, etc.), drug transporters (multispecific organic anion transporter, P-glycoprotein, alpha-1-acid glycoprotein, etc.), and drug-metabolizing enzymes (cytochrome P450s and other enzymes); (2) the structure and function of all genetic variants of drug receptors, transporters, and metabolizing enzymes; (3) the induction, repression, and inhibition of all components involved in drug disposition; (4) the development of noninvasive in vivo methods to determine the physiological significance of various components in the handling of specific therapeutic agents in humans; (5) the mechanism of idiosyncratic adverse drug reactions; and (6) the pharmacokinetic and pharmacodynamic relationships to explain the individual differences in therapeutic efficacy and drug safety. "
2.	Uveitis 01/01/2014 - "An anti-interleukin-2 receptor drug attenuates T- helper 1 lymphocytes-mediated inflammation in an acute model of endotoxin-induced uveitis." 01/01/2014 - "The aim of the present study was to evaluate the anti-inflammatory efficacy of Daclizumab, an anti-interleukin-2 receptor drug, in an experimental uveitis model upon a subcutaneous injection of lipopolysaccharide into Lewis rats, a valuable model for ocular acute inflammatory processes. "
3.	Urticaria (Hives) 07/01/1989 - "Since pirenzepine, an antimuscarinic receptor drug, exerts a cytoprotective activity on digestive mucosa, the authors evaluated the clinical efficacy of pirenzepine and terfenadine (antihistamine), alone or associated, in the treatment of patients with urticaria-angioedema syndrome due to food allergy. "
4.	Food Hypersensitivity (Food Allergy) 07/01/1989 - "Since pirenzepine, an antimuscarinic receptor drug, exerts a cytoprotective activity on digestive mucosa, the authors evaluated the clinical efficacy of pirenzepine and terfenadine (antihistamine), alone or associated, in the treatment of patients with urticaria-angioedema syndrome due to food allergy. "
5.	Angioedema 07/01/1989 - "Since pirenzepine, an antimuscarinic receptor drug, exerts a cytoprotective activity on digestive mucosa, the authors evaluated the clinical efficacy of pirenzepine and terfenadine (antihistamine), alone or associated, in the treatment of patients with urticaria-angioedema syndrome due to food allergy. "

Related Drugs and Biologics

1.	Enzymes
2.	daclizumab (dacliximab)
3.	Multidrug Resistance-Associated Proteins
4.	P-Glycoprotein
5.	Terfenadine (Seldane)
6.	Pirenzepine
7.	Orosomucoid (Seromucoid)
8.	Ion Channels (Ion Channel)
9.	Cytochromes
10.	Neurotransmitter Agents (Neurotransmitter)

Related Therapies and Procedures

1.	Subcutaneous Injections
2.	Drug Therapy (Chemotherapy)