Cholinergic Receptors

Cell surface proteins that bind acetylcholine with high affinity and trigger intracellular changes influencing the behavior of cells. Cholinergic receptors are divided into two major classes, muscarinic and nicotinic, based originally on their affinity for nicotine and muscarine. Each group is further subdivided based on pharmacology, location, mode of action, and/or molecular biology.

Also Known As:

Networked: 856 relevant articles (5 outcomes, 70 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Vincent, Angela: 11 articles (06/2015 - 03/2002)
2.	Lindstrom, Jon: 4 articles (08/2015 - 01/2008)
3.	Beeson, David: 4 articles (06/2015 - 10/2002)
4.	Motomura, Masakatsu: 4 articles (11/2011 - 02/2005)
5.	Fisher, Stephen K: 4 articles (04/2010 - 10/2003)
6.	Heacock, Anne M: 4 articles (04/2010 - 10/2003)
7.	Dalakas, Marinos C: 3 articles (11/2015 - 12/2012)
8.	Grando, Sergei A: 3 articles (11/2015 - 01/2004)
9.	Leite, Maria Isabel: 3 articles (06/2015 - 10/2005)
10.	Willcox, Nick: 3 articles (08/2014 - 10/2002)

Related Diseases

1.	Hypersensitivity (Allergy) 12/01/1996 - "We found hypersensitivity of muscarinic cholinergic receptors in the frontal cortex of patients with PD by using PET. " 02/01/1991 - "Cholinergic nasal hyperresponsiveness in nasal allergy may be due to changes of the characteristics in muscarinic cholinergic receptors. " 01/01/1987 - "In subjects with nasal allergy, a decrease in density of beta- and alpha 1-adrenergic receptors and an increase in density of muscarinic cholinergic receptors were observed. " 01/01/1987 - "Changes of adrenergic and muscarinic cholinergic receptors in nasal mucosa in nasal allergy." 01/01/1983 - "Adrenergic and cholinergic receptors in human nasal mucosa in cases of nasal allergy."
2.	Body Weight (Weight, Body) 04/01/1991 - "The combination pretreatment also gave better protection against soman-induced body weight loss and decreased water consumption and attenuated the down-regulation of cholinergic receptors which occurred when physostigmine alone was used. " 12/01/2011 - "Rats treated with arsenic (sodium arsenite, 20mg/kg body weight, p.o., 28 days) exhibited a significant decrease in the learning activity, assessed by passive avoidance response associated with decreased binding of (3)H-QNB, known to label muscarinic-cholinergic receptors in hippocampus (54%) and frontal cortex (27%) as compared to controls. " 01/01/1992 - "Chronic administration of manganese chloride (5 mg Mn/kg body weight/day) during nine weeks, did not affect the [3H]-quinuclidinyl benzilate binding to muscarinic cholinergic receptors in mouse brain. " 01/01/1991 - "Since stimulation of adrenergic or cholinergic receptors has no effect on glomerular filtration rate, the antidiuresis and significant delay in urinary flow observed after lateral hypothalamic stimulation with carbachol (CCh) (0.036 +/- 0.005 to 0.019 +/- 0.003 microliters min-1 100 g body weight-1) and noradrenaline (Nad) (0.024 +/- 0.005 to 0.025 +/- 0.004 microliters min-1 100 g body weight-1) are secondary to an increase in distal tubular fluid reabsorption (DFR). "
3.	Amnesia (Dissociative Amnesia) 11/01/2013 - "Hippocampal α7-nicotinic cholinergic receptors modulate memory reconsolidation: a potential strategy for recovery from amnesia." 05/01/1994 - "5. These results suggest that the direct stimulation of cholinergic receptors is more effective for scopolamine-induced amnesia than the indirect stimulation of cholinergic receptors by cholinesterase inhibitors in the habituation task." 09/01/1977 - "Stimulation of dopamine receptors with piribedil and acetylcholine receptors with pilocarpine was ineffective in reversing amnesia. "
4.	Central Nervous System Diseases (CNS Diseases) 05/01/2013 - "Understanding the type of ACh receptors involved in neuroprotection in the rat retina could ultimately lead to therapeutic treatment for any CNS disease that involves excitotoxicity."
5.	Acromegaly 04/01/1988 - "Role of cholinergic receptors blockade by atropine on growth hormone (GH)--releasing hormone (GHRH)--induced GH release in active or surgically cured acromegaly."

Related Drugs and Biologics

1.	Atropine (Hyoscyamine)
2.	Cholinesterase Inhibitors (Anticholinesterases)
3.	Histamine (Histamine Dihydrochloride)
4.	Scopolamine (Hyoscine)
5.	Methacholine Chloride (Methacholine)
6.	Physostigmine
7.	Growth Hormone (Somatotropin)
8.	Hormones
9.	Soman
10.	neurotropin

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Denervation
3.	Thymectomy
4.	Therapeutics
5.	Axotomy