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beta Adrenergic Receptors

Subscribe to New Research on beta Adrenergic Receptors

One of two major pharmacologically defined classes of adrenergic receptors. The beta adrenergic receptors play an important role in regulating CARDIAC MUSCLE contraction, SMOOTH MUSCLE relaxation, and GLYCOGENOLYSIS.

Also Known As:

Receptors, Adrenergic, beta; Receptor, Adrenergic, beta; Adrenergic beta Receptors; Receptors, beta Adrenergic; beta-Receptors, Adrenergic; Adrenergic beta-Receptors; Receptors, beta-Adrenergic; beta-Adrenergic Receptors

Networked: 720 relevant articles (11 outcomes, 66 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins
- Proteins: 90489
  - Membrane Proteins: 5300
    - Cell Surface Receptors: 753

Experts

1.	Schuller, Hildegard M: 4 articles (02/2012 - 12/2004)
2.	Rockman, Howard A: 3 articles (10/2011 - 06/2005)
3.	Liggett, Stephen B: 3 articles (12/2008 - 08/2003)
4.	Trimarco, Bruno: 3 articles (12/2008 - 09/2005)
5.	Dorn, Gerald W: 3 articles (12/2008 - 12/2002)
6.	Schuller, H M: 3 articles (07/2002 - 11/2000)
7.	Li, Xia: 2 articles (04/2014 - 03/2005)
8.	Al-Wadei, Hussein A N: 2 articles (02/2012 - 01/2012)
9.	Al-Wadei, Mohammed H: 2 articles (02/2012 - 01/2012)
10.	Taylor, Matthew R G: 2 articles (06/2011 - 01/2011)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2010 - "Beta-adrenergic receptors in cancer: therapeutic implications." 07/01/2002 - "Our data suggest that a significant subset of human breast cancers is under control of beta-adrenergic receptors via stimulation of the AA-cascade. " 09/01/1989 - "These findings suggest an important role of beta-adrenergic receptors in the regulation of cell proliferation in lung tumors comprised of this cell type." 07/01/1989 - "Spontaneous mammary tumors of aging (18-22 months) female rats have high levels of beta-adrenergic receptors. " 07/01/1988 - "In the Leydig tumor cells, approx 25% of the beta-adrenergic receptors was identified as beta 1-receptors, whereas approx 75% of the receptors were of the beta 2-subtype. "
2.	Heart Failure 08/01/1994 - "While most prior studies examined late stages of heart failure, we determined initial changes of beta-adrenergic receptors (beta-AR) during left ventricular chronic volume and pressure overload. " 05/01/1989 - "This study was designed to determine changes in the number of beta-adrenergic receptors of circulating lymphocytes in patients with varying degrees of congestive heart failure. " 11/27/2007 - "Downregulation of beta-adrenergic receptors (betaARs) under conditions of heart failure requires receptor targeting of phosphoinositide 3-kinase (PI3K)-gamma and redistribution of betaARs into endosomal compartments. " 01/01/2007 - "Antagonists of beta-adrenergic receptors (beta-ARs) have become a main therapeutic regimen for the treatment of heart failure even though the mechanisms of their beneficial effects are still poorly understood. " 07/01/2006 - "Beta-adrenergic receptors signaling and heart failure in mice, rabbits and humans."
3.	Burns 01/01/2013 - "Pharmacological agents that block beta-adrenergic receptors have been associated with improved outcome in burn injury. " 01/01/1996 - "In the present study, myocardial tissues were used as a model of beta-adrenergic receptors to study burn injury-induced alterations in receptors and in signal transduction. " 11/01/1993 - "Using this model, we have developed techniques to characterize and quantitate changes in beta-adrenergic receptors (beta AR) in the guinea pig heart after burn injury. " 05/01/1992 - "Burn-induced alterations in cardiac beta-adrenergic receptors." 05/01/1992 - "Therefore the purpose of this study was to examine the inotropic response to isoproterenol, a beta-adrenergic agonist, and burn-induced alterations in beta-adrenergic receptors (beta-AR) in adult guinea pig hearts. "
4.	Infection 01/15/1997 - "As assessed by radioligand binding, Adeno-beta2AR infection led to approximately 20-fold overexpression of beta-adrenergic receptors. " 09/29/1989 - "At 48 hr post-infection, the level of expression of beta-adrenergic receptors was approximately 12 million/cell. " 01/01/1995 - "Experimental Chagas' disease (45 to 90 days post-infection) showed serious cardiac alterations in the contractility and in the pharmacological response to beta adrenergic receptors in normal and T. " 04/01/1991 - "The relationships between the activation of membrane bound alpha-1 and beta-adrenergic receptors, the cyclic nucleotide response and Ca2+ channel binding were studied in a cellular model of latent virus infection (Herpes simplex, Type-2) in a human embryonal cell line. " 04/01/1980 - "Persistent paramyxovirus infections and behaviour of beta-adrenergic receptors in C-6 rat glioma cells."
5.	Anoxia (Hypoxia) 09/01/2009 - "We utilized echocardiography and pressure-volume (PV) loop analyses to determine whether LV contractility was decreased in inbred C57BL/6J mice exposed to IH and whether blockade of beta-adrenergic receptors modified the response to hypoxia. " 12/01/1995 - "A modulation of Gs and/or G1 protein alpha-subunits may be associated with the downregulation of the beta-adrenergic receptors previously found in chronic hypoxia. " 10/01/1993 - "Chronic hypoxia induces a hyperadrenergic state which down-regulates beta-adrenergic receptors (beta-AR) in the heart. " 10/01/1993 - "Visualization of high- and low-affinity beta-adrenergic receptors in rat lung: upregulation by chronic hypoxia." 12/01/1992 - "Transcriptional regulation of left ventricular beta-adrenergic receptors during chronic hypoxia."

Related Drugs and Biologics

1.	Adenylate Cyclase (Adenylyl Cyclase)
2.	Isoproterenol (Isoprenaline)
3.	carvedilol (Coreg)
4.	Catecholamines
5.	Propranolol (Inderal)
6.	Epinephrine (Adrenaline)
7.	Phentolamine (Z-Max)
8.	Steroids
9.	Liver Glycogen
10.	Clenbuterol

Related Therapies and Procedures

1.	Sympathectomy (Sympathectomies)
2.	Surgical Instruments (Clip)
3.	Resuscitation
4.	Ligation
5.	Vagus Nerve Stimulation