Reagins

Antibodies, especially IGE, that bind to tissue of the same species so that ANTIGENS induce HISTAMINE RELEASE and other vasoactive agents. HYPERSENSITIVITY is the clinical manifestation.

Also Known As:

Networked: 835 relevant articles (31 outcomes, 69 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Mabey, David: 9 articles (01/2016 - 07/2002)
2.	Klausner, Jeffrey D: 8 articles (01/2022 - 03/2006)
3.	Lukehart, Sheila A: 8 articles (01/2021 - 02/2004)
4.	Hung, Chien-Ching: 6 articles (09/2021 - 10/2010)
5.	Mitjà, Oriol: 6 articles (01/2021 - 01/2012)
6.	Pillay, Allan: 6 articles (01/2021 - 05/2004)
7.	Liu, Wen-Chun: 5 articles (09/2021 - 10/2010)
8.	Sun, Hsin-Yun: 5 articles (09/2021 - 01/2014)
9.	Vermund, Sten H: 5 articles (10/2018 - 02/2007)
10.	Marra, Christina M: 5 articles (04/2016 - 02/2004)

Related Diseases

1.	Syphilis 05/01/2008 - "The aim of this study was to detect the sensitivity and specificity of rapid syphilis diagnostic tests (immunochromatographic strip [ICS] test and rapid test device [RTD]) performed by low-skilled paramedics in field clinics and by highly-skilled technologists in laboratories and compare them with the gold standard (rapid plasma reagin [RPR] and Treponema pallidum haemagglutination [TPHA]) tests for diagnosis of syphilis. " 12/01/2006 - "A study found screening (with rapid plasma reagin (RPR)) pregnant women for maternal syphilis was cost-effective in Mwanza, Tanzania. " 01/01/2023 - "Rapid plasma reagin (RPR) test of serum showed positive results for syphilis. " 01/01/2019 - "The treponemal syphilis component of the dual rapid test was compared with the Treponema pallidum hemagglutination assay (TPHA) as a gold standard comparator, both alone or in combination with a nontreponemal test, the rapid plasma reagin test. " 01/01/2018 - "The analytical performance of the AIX1000 system, a fully automated and recently FDA-cleared rapid plasma reagin (RPR) system, was evaluated by comparison to a manual RPR test in a traditional syphilis testing algorithm. "
2.	Sexually Transmitted Diseases (Sexually Transmitted Disease) 08/01/2008 - "Outside Europe the rapid plasma reagin test (RPR) or venereal disease research laboratory test is most often used for screening purposes. " 09/01/2022 - "The analytical study performed revealed positive VDRL (Venereal Disease Research Laboratory) and RPR (Rapid Plasma Reagin). " 01/01/2023 - "Venereal disease research laboratory (VDRL) test and Treponema pallidum hemagglutination assay (TPHA) were found positive with high titer (1:1280) and rapid plasma reagin (RPR) titer of 1:64 in blood. " 07/01/2022 - "Reactive serological titer of rapid plasma reagin test and venereal disease research laboratory test confirmed the diagnosis." 07/01/2020 - "All the samples were subjected to Venereal Disease Research Laboratory (VDRL), rapid plasma reagin (RPR), ELISA, and TPHA tests. "
3.	Neurosyphilis (General Paresis of the Insane) 01/01/2018 - "However, it is unknown whether serum rapid plasma reagin (RPR) titer can serve as a surrogate for determining the efficacy of treatment in general paresis (GP) remains unknown. " 11/01/2016 - "Only 43.3 % of misdiagnosed patients and 30.8 % of general paresis patients had positive results for the CSF rapid plasma reagin (RPR) test; 96.4 % patients had abnormal neuroimaging. " 03/01/2022 - "Rapid plasma reagin was reactive and cerebrospinal fluid studies showed findings consistent with a diagnosis of neurosyphilis. " 01/01/2020 - "His serum and cerebrospinal fluid studies were positive for Rapid Plasma Reagin and Veneral Disease Research Laboratory tests, respectively, suggesting a diagnosis of paretic neurosyphilis. " 01/01/2015 - "In the 43 cases with positive serum rapid plasma reagin (RPR) and TPPA tests, 18 patients met the criteria of this study: 11 presented with symptoms of general paresis, and seven had typical presentations of TD. "
4.	Infections 02/28/1927 - "Although a number of questions require further study, yet it seems likely that this antigenic activity of the microbes or their products plays a part in the production of the Wassermann reagins in infections with spirochetes and trypanosomes." 12/01/2022 - "However, the discovery of positive serology for Treponema pallidum infection on routine tests on admission prompted analysis of cerebrospinal fluid, which was also positive on Treponema pallidum hemagglutination (TPHA), rapid plasma reagin (RPR), and treponemal antibody absorption (FTA-ABS) tests. " 01/01/2021 - "Transmission can be assessed using rapid plasma reagin (RPR) tests, reflecting current or recent infection, but RPR is operationally impractical. " 07/02/2020 - "If TPHA was positive, a venous blood sample was collected from the mother to confirm active infection using Rapid Plasma Reagin (RPR). " 02/01/2020 - "Sixty New Zealand white male rabbits were challenged with Nichols or Amoy Treponema pallidum strains, and the rapid plasma reagin (RPR) test was performed to quantify non-treponemal antibody titres during the infection course. "
5.	Atopic Dermatitis (Atopic Eczema) 03/01/1995 - "Analysis of immunograms of 189 children with allergic diseases of the reagin type (55 with atopic bronchial asthma, 33 with atopic dermatitis, 101 with respiratory allergosis) helped single out a complex of immunological parameters which markedly and statistically reliably change in this type of allergy in comparison with a group of healthy children (n = 25). " 01/01/2002 - "The combination of the local disinfection therapy against Staphylococcus aureus with the conventional therapy for atopic dermatitis has been widely used, and the improvement in skin lesions has been reported to be associated with a remarkable decrease in IgE levels and reagin antibody titers. "

Related Drugs and Biologics

1.	Enzymes
2.	Latex
3.	Antibodies
4.	Immunoglobulin M (IgM)
5.	Immunoglobulin G (IgG)
6.	Antigens
7.	Immunosorbents
8.	Immunoglobulin E (IgE)
9.	bioplex
10.	Coloring Agents (Dyes)

Related Therapies and Procedures

1.	Therapeutics
2.	Prenatal Care (Care, Prenatal)
3.	Aftercare (After-Treatment)
4.	Intramuscular Injections
5.	Renal Replacement Therapy (Therapies, Renal Replacement)