Quercetin

08/11/2010 - "Furthermore, in vivo experiments showed that quercetin treatment resulted in a significant reduction in tumor volume over 6 weeks, and apoptosis-related protein induction by quercetin was significantly higher in the 100 mg/kg treated group compared to the control group. "
05/01/2012 - "It was found that both quercetin and QS can inhibit the growth of cancer cells in a dose-dependent manner, with the IC(50) values of 40.2 and 28.0 μM for LoVo cells and 30.8 and 19.9 μM for MCF-7 cells, respectively, suggesting QS was more effective against the cancer cells than quercetin. "
06/01/2014 - "Quercetin (QCT) is known to be effective in the treatment of cancer, by reducing the cell viability of different cancer cell lines. "
06/01/1996 - "In contrast, quercetin which was also only weakly effective in the mammary model, caused a dose-dependent enhancement of tumors induced by AOM in the colon model."
07/01/2003 - "For example, quercetin and related phenolic compounds, present in teas, wines, and other plant products, have been shown to cause their cytotoxic effects on tumor cells in culture, proposing their protective effects against the development of cancer. "

03/01/2014 - "Exercise, but not quercetin, ameliorates inflammation, mitochondrial biogenesis, and lipid metabolism in skeletal muscle after strenuous exercise by high-fat diet mice."
04/25/2015 - "Quercetin pretreatment effectively ameliorates LPS-induced ALI, largely through suppression of inflammation and oxidative stress, and may thus have therapeutic potential in the prevention of this disease."
07/01/2008 - "However, quercetin at the levels provided was effective in reducing circulating markers of inflammation observed in animals on an HF diet at 8W."
08/02/2004 - "Although quercetin is generally considered to provide protection against oxidative injury and inflammation, recent studies have demonstrated that its cytoprotective effects occur within a narrow concentration range. "
09/15/2015 - "Quercetin intraperitoneal administration ameliorates lipopolysaccharide-induced systemic inflammation in mice."

01/01/2014 - "Quercetin caused no significant reduction in body weight or adipose tissue sizes. "
09/01/2014 - "The aim of this study was to investigate the effects and underlying molecular mechanisms of the flavonoid quercetin on hepatic lipid metabolism in mice with high-fat diet induced body weight gain and hepatic lipid accumulation. "
01/01/2013 - "In the atherosclerotic regression study, the animals were fed with the HCD for 90 d and then supplemented with quercetin (25 mg/kg of body weight) for another 90 d. "
01/01/2013 - "In the atherosclerotic progression study, quercetin (25 mg/kg of body weight) was administered with the HCD for 90 d. "
07/01/2005 - "To assess the long-term tissue distribution of quercetin, 2 groups of rats were given a 0.1 or 1% quercetin diet [approximately 50 or 500 mg/kg body weight (wt)] for 11 wk. In addition, a 3-d study was done with pigs fed a diet containing 500 mg quercetin/kg body wt. Tissue concentrations of quercetin and quercetin metabolites were analyzed with an optimized extraction method. "

08/15/2012 - "Quercetin at 50 mg/kg body wt, orally 1h prior to hypoxia exposure, was considered as the optimum dose, due to a significant reduction in the level of brain water content and cerebral transvascular leakage (P < 0.001), as compared to control (24 h hypoxia). "
11/15/2015 - "We hypothesized that quercetin exerts protective effects against this disease; thus, a chronic hypoxia model of PAH was generated using male Sprague-Dawley rats, which were treated with quercetin. "
06/01/2007 - "[Protective effects of Astragaloside and Quercetin on rat myocardial cells after hypoxia]."
01/01/2015 - "Quercetin ameliorates hypobaric hypoxia-induced memory impairment through mitochondrial and neuron function adaptation via the PGC-1α pathway."
12/01/2013 - "Behavioral studies showed that quercetin reversed the hypobaric hypoxia-induced memory impairment. "

07/01/2009 - "Quercetin administration ameliorates pulmonary complications of cirrhosis in rats."
01/01/2012 - "This study aimed to assess the antioxidant activity of quercetin (Q) in an experimental model of cirrhosis induced by CCl(4) inhalation. "
07/01/2007 - "The present study is the first report of genotoxic/antigenotoxic effects of quercetin in a model of animal cirrhosis. "
08/01/2014 - "These results suggest that quercetin may be an effective therapeutic strategy in the treatment of patients with liver damage and fibrosis."
08/01/2013 - "Quercetin inhibits radiation-induced skin fibrosis."