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Pyridones

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Pyridine derivatives with one or more keto groups on the ring.

Also Known As:

Pyridinones

Networked: 10 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 60
- 1-Ring Heterocyclic Compounds
  - Pyridines: 41
    - Pyridones: 10

Experts

1.	Müller, Stephan: 1 article (08/2015)
2.	Arndt, Kirsten: 1 article (08/2015)
3.	Lotz, Ralf R H: 1 article (08/2015)
4.	Lenter, Martin: 1 article (08/2015)
5.	Budzinski, Ralph: 1 article (08/2015)
6.	Stenkamp, Dirk: 1 article (08/2015)
7.	Maier, Gerd-Michael: 1 article (08/2015)
8.	Lehmann, Thorsten: 1 article (08/2015)
9.	Rudolf, Klaus: 1 article (08/2015)
10.	Kley, Jörg T: 1 article (08/2015)

Related Diseases

1.	Obesity 08/15/2015 - "As part of our search for safe and effective MCH-R1 antagonists for the treatment of obesity, two series of pyridones and pyridazinones were evaluated. "
2.	Neoplasms (Cancer) 06/01/1977 - "[Anti-tumor activities of some seventy compounds related to lactams and pyridones (author's transl)]." 04/01/2003 - "In conclusion (a) rat hepatocytes have a much greater capacity to take up NTBI than the rat hepatoma cell line (Q7), (b) all chelators bind NTBI much more effectively during the uptake phase than in the mobilization of Fe which has been stored from NTBI and (c) while DFP is the most active chelator, other multidentate pyridinones have potential in the treatment of Fe overload, particularly at lower, more readily clinically available concentrations, and during cancer chemotherapy, by removing plasma NTBI."
3.	Neuralgia (Stump Neuralgia) 08/15/2013 - "Synthesis and the 5-HT6 receptor antagonistic effect of 3-arylsulfonylamino-5,6-dihydro-6-substituted pyrazolo[3,4]pyridinones for neuropathic pain treatment."
4.	Lymphoid Leukemia 06/01/1990 - "The 4- and 5-pyrrolizinyl-2-halopyridinium iodides and the corresponding pyridones were evaluated against P388 lymphocytic leukemia in vivo. "
5.	Inflammation 07/01/2011 - "Further optimization produced the highly selective and potent pyridinones 2 and 3. These inhibitors exhibited activity in both acute and chronic models of inflammation."

Related Drugs and Biologics

1.	Hydroxylamine (Hydroxylamine Hydrochloride)
2.	RNA-Directed DNA Polymerase (Reverse Transcriptase)
3.	Lactams
4.	Isoflurophate (DFP)
5.	Iron
6.	Iodides
7.	Deferoxamine (Desferal)
8.	Chelating Agents
9.	Carrageenan
10.	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)