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Hyperglobulinemic Purpura

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Purplish or brownish red discoloration of the skin associated with increase in circulating polyclonal globulins, usually GAMMA-GLOBULINS. This syndrome often occurs on the legs of women aged 20 to 40 years.

Also Known As:

Purpura, Hyperglobulinemic; Benign Hyperglobulinemic Purpura of Waldenström; Hypergammaglobulinemic Purpura of Waldenstrom; Hyperglobulinemic Purpura of Waldenström; Waldenstrom Hyperglobulinemic Purpura; Hyperglobulinemic Purpura, Waldenstrom; Hyperglobulinemic Purpuras; Purpura, Waldenstrom Hyperglobulinemic; Purpuras, Hyperglobulinemic; Waldenstrom Hypergammaglobulinemic Purpura; Waldenström Hyperglobulinemic Purpura

Networked: 15 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Polymyositis
2.	Vasculitis (Vasculitides)
3.	Sjogren's Syndrome (Sjogren Syndrome)
4.	Infection
5.	Hypergammaglobulinemia (Hyperimmunoglobulinemia)

Experts

1.	Jakez-Ocampo, Juan: 1 article (01/2015)
2.	Llorente, Luis: 1 article (01/2015)
3.	Atisha-Fregoso, Yemil: 1 article (01/2015)
4.	Hamerschlak, N: 1 article (01/2006)
5.	Ribeiro, A A F: 1 article (01/2006)
6.	Goldenberg, J: 1 article (01/2006)
7.	Chahade, W H: 1 article (01/2006)
8.	Scheinberg, M: 1 article (01/2006)
9.	Ferreira, E: 1 article (01/2006)
10.	Kiss, M H: 1 article (01/2006)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Hyperglobulinemic Purpura:

1.	Antigen-Antibody Complex (Immune Complex)IBA 06/01/1984 - "Waldenström's hyperglobulinemic purpura: an unusual immune complex disorder." 05/01/1979 - "Immune complex vasculitis, polymyositis, and hyperglobulinemic purpura."
2.	Cytostatic AgentsIBA 04/20/1968 - "[On the therapy of Waldenström's hyperglobulinemic purpura by suppression of protein biosynthesis with cytostatic drugs]."
3.	Thioguanine (Tioguanine)FDA Link 04/04/1963 - "Treatment of two cases of hyperglobulinemic purpura with thioguanine."
4.	Rose BengalIBA 02/01/1991 - "A diagnosis of primary SjS and hyperglobulinemic purpura was made on the basis of positive staining with Rose Bengal stain, sialography of the parotid gland and histological examination of the salivary gland of the lip. "
5.	Prednisone (Sone)FDA LinkGeneric 01/01/2015 - "Hyperglobulinemic purpura disappeared, and prednisone tapering succeeded. "
6.	Phenylbutazone (Butazolidin)FDA Link 11/15/1968 - "[A fatal pathological condition with hyperglobulinemic purpura and polymyositis after phenylbutazone]."
7.	MacroglobulinsIBA 02/01/1957 - "[Waldenström's hyperglobulinemic purpura associated with macroglobulins]."
8.	Immunoglobulin A (IgA)IBA 01/01/1980 - "We described a patient who developed characteristic lesions of hyperglobulinemic purpura in the course of IgA myeloma. "
9.	Ethamsylate (Etamsylate)IBA 03/01/1996 - "Therapeutic effect of ethamsylate in a case of hyperglobulinemic purpura associated with Sjogren's syndrome."
10.	Erythema elevatum diutinumIBA 09/01/1984 - "Patients with hyperglobulinemic purpura, which may be a subset of leukocytoclastic vasculitis, should be examined for associated conditions."

Therapies and Procedures

1.	Plasmapheresis 07/11/1981 - "Treatment by plasmapheresis of associated hyperglobulinemic purpura]."