Purine Nucleosides

06/01/2005 - "In this study, we wanted to investigate the effect of purine nucleosides on cellular responses to chemical hypoxia. "
01/01/2012 - "Identification of agents that reduce renal hypoxia-reoxygenation injury using cell-based screening: purine nucleosides are alternative energy sources in LLC-PK1 cells during hypoxia."
03/01/2004 - "Purine nucleosides support the neurite outgrowth of primary rat cerebellar granule cells after hypoxia."
12/01/1992 - "This treatment also significantly prevented the release of purine nucleosides and bases during hypoxia. "
01/01/1977 - "The protective effects of purine nucleosides on the release of intracellular enzymes in hypoxia [proceedings]."

09/01/2011 - "The present work is devoted to the study of the effects of some synthetic derivatives of purine nucleosides on activity of highly purified PNP from rabbit spleen and also from human healthy and tumor tissues of lung and kidneys. "
05/01/2009 - "Separation and identification of purine nucleosides in the urine of patients with malignant cancer by reverse phase liquid chromatography/electrospray tandem mass spectrometry."
06/01/1979 - "[75Se-substituted purine nucleosides as potential tumor diagnostica. "
07/01/1985 - "In HT-29 tumor cells, OHUrd cytotoxicity could be prevented by coincubation with uridine or cytidine but not by pyrimidine deoxyribonucleosides or by purine nucleosides. "
04/15/2015 - "Glycine is the smallest amino acid used in protein synthesis, but it is also a very important precursor for the biosynthesis of other nitrogen-containing metabolites, such as purine nucleosides and nucleotides for synthesis of RNA, DNA etc. Abnormalities in glycine metabolism therefore cause diseases such as cancer. "

06/01/1981 - "These studies provide a better understanding of the control of the OPRT-ODC reactions in the cell and provide additional insight into the basis of pyrimidine starvation induced by purine nucleosides."
02/01/1965 - "EFFECT OF STARVATION AND OF ADMINISTRATION OF PURINES AND PURINE NUCLEOSIDES."

01/01/2007 - "tuberculosis, we have initiated studies to characterize the enzymes that are involved in salvage of purine nucleosides. "

09/01/2014 - "Purine nucleosides and nucleobases play key roles in the physiological response to vascular ischemia/reperfusion events. "
10/01/1994 - "[Effect of purine nucleosides on the contractile function of the rat heart in ischemia and reperfusion]."
05/01/1992 - "[Hemodynamic effects of purine nucleosides in regional ischemia and reperfusion]."
01/01/2009 - "Adenosines, endogenous purine nucleosides, appear in the extracellular space under metabolically stressful conditions associated with ischemia, inflammation, and cell damage. "
03/01/1990 - "Thus, functional and/or anatomic alterations of the coronary vascular bed and a greater loss of purine nucleosides during reperfusion are likely responsible for the attenuated compensatory response to ischemia and reperfusion in left ventricular hypertrophy induced by chronic pressure overload. "