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Pulmonary Subvalvular Stenosis (Pulmonary Infundibular Stenosis)

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Narrowing below the PULMONARY VALVE or well below it in the infundibuluar chamber where the pulmonary artery originates, usually caused by a defective VENTRICULAR SEPTUM or presence of fibrous tissues. It is characterized by restricted blood outflow from the RIGHT VENTRICLE into the PULMONARY ARTERY, exertional fatigue, DYSPNEA, and chest discomfort.

Also Known As:

Pulmonary Infundibular Stenosis; Infundibular Stenoses, Pulmonary; Pulmonary Infundibular Stenoses; Pulmonary Stenoses, Subvalvular; Pulmonary Stenosis, Subvalvular; Pulmonary Subvalvular Stenoses; Stenoses, Pulmonary Infundibular; Stenoses, Pulmonary Subvalvular; Stenoses, Subvalvular Pulmonary; Stenosis, Pulmonary Infundibular; Stenosis, Pulmonary Subvalvular; Stenosis, Subvalvular Pulmonary; Subvalvular Pulmonary Stenoses; Subvalvular Pulmonary Stenosis; Subvalvular Stenoses, Pulmonary; Subvalvular Stenosis, Pulmonary; Conus, Obstructive Subaortic; Subaortic Conus, Obstructive; Infundibular Stenosis, Pulmonary; Obstructive Subaortic Conus

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Cardiovascular Diseases: 37259
- Heart Diseases: 18762
  - Heart Valve Diseases: 960
    - Pulmonary Valve Stenosis: 869
      - Pulmonary Subvalvular Stenosis: 4
  - Ventricular Outflow Obstruction: 94
    - Pulmonary Valve Stenosis: 869
      - Pulmonary Subvalvular Stenosis: 4

Related Diseases

1.	Neurofibromatoses (Neurofibromatosis)
2.	Noonan Syndrome (Female Pseudo-Turner Syndrome)
3.	Demyelinating Diseases (Demyelinating Disease)

Experts

1.	Ma, S K: 1 article (07/2002)
2.	Wan, T S: 1 article (07/2002)
3.	Au, W Y: 1 article (07/2002)
4.	Kwong, Y L: 1 article (07/2002)
5.	Jim, M H: 1 article (07/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Pulmonary Subvalvular Stenosis:

1.	Dichlorodiphenyldichloroethane (DDD)IBA 11/01/1999 - "Sequelae of DDD pacing in patients with pulmonary infundibular stenosis." 07/01/1999 - "We evaluated acute effects of DDD pacing (right atrium sensed and left ventricle paced) in 3 patients with pulmonary infundibular stenosis and found a decrease in dynamic right ventricular outflow gradient in all of them. " 07/01/1999 - "Acute effects of DDD pacing in patients with pulmonary infundibular stenosis."
2.	monosomy Chromosome 7IBA 07/01/2002 - "Subvalvular pulmonary stenosis, demyelination and myelodysplasia with monosomy 7." 07/01/2002 - "We report a 23-year-old male with subvalvular pulmonary stenosis (PS) presenting with concurrent acute demyelinating neuropathy and myelodysplasia with monosomy 7. There was no stigmata of Noonan syndrome or neurofibromatosis, nor any family history of cardiac or hematologic disorders. "
3.	Complete atrioventricular septal defectIBA 09/01/1981 - "The case of an eight year old child with complete atrioventricular canal, pulmonary infundibular stenosis and persistent left superior vena cava draining into the coronary sinus is reported. "