Pulmonary Embolism

09/01/1990 - "Low-dose subcutaneous heparin 5,000 IU commencing 2 hours preoperatively and continuing 12 hourly until the patient is fully mobile is unequivocally effective in preventing DVT in medical and surgical patients and, most importantly, significantly reduces the incidence of fatal postoperative pulmonary embolism and total mortality. "
06/01/1995 - "Whether thrombolysis is superior to heparin in subacute intermediate pulmonary embolism has not been proven unequivocally in terms of mortality or clinically important endpoints. "
03/01/1983 - "The efficacy of low dosage heparin in the prevention of pulmonary embolism has been assessed in a group of 177 "high risk" patients undergoing hip replacement operations compared with a control group of 236 "high risk" patients not so treated. "
12/01/1976 - "There is reasonable evidence that heparin in low doses also offers a satisfactory protection against fatal pulmonary embolism for patients at high risk after general abdominothoracic operations. "
01/01/1967 - "[Two cases of massive pulmonary embolism treated successfully with heparin + CY 58]."

11/01/1999 - "Although the PREPIC study, first prospective controlled trial on caval filters, confirmed their efficacy for preventing pulmonary embolism, the addition of caval filters to preventive or curative anticoagulant treatment in high-risk patients is still a matter of debate, because "very high-risk" settings despite anticoagulant treatment remain poorly defined. "
12/01/2020 - "The safety and efficacy of direct oral anticoagulants (DOACs) in intermediate-high risk pulmonary embolism (PE) are unknown. "
10/01/2012 - "Although improved surgical techniques and widespread use of anticoagulants have substantially reduced the incidence of thromboembolic events, venous thromboembolic disease is still a dangerous complication and, in these patients, pulmonary embolism remains the main cause of death. "
01/01/1993 - "Although oral anticoagulants appear to be particularly effective for the prevention of fatal pulmonary embolism, it is not clear that their efficacy is directly related to the prothrombin time."
11/01/2001 - "This study reports the efficacy of adjusted low-dose oral anticoagulants in the prevention of fatal pulmonary embolism after hip fracture. "

12/01/2015 - " mainstay of treatment for pulmonary thromboembolism in pregnancy is anticoagulation with low molecular weight heparin for a minimum of 3 months in total duration and until at least 6 weeks postnatal. "
06/01/2007 - "Home treatment of sural and femoral-popliteal DVT using LMWH represents a safe and effective method in the prevention of pulmonary embolism and encourages the process of recanalization of the thrombosed vessel, especially in cases of sural and/or popliteal DVT. "
09/01/2005 - "Low-molecular-weight heparin (LMWH) appears to be safe and effective for treating pulmonary embolism (PE), but its cost-effectiveness has not been assessed. "
01/01/2009 - "The authors conducted a prospective study of the efficacy of prophylactic use of low-molecular-weight heparin to prevent pulmonary thromboembolism. "
10/01/2004 - "Pulmonary embolism in medical patients: improved diagnosis and the role of low-molecular-weight heparin in prevention and treatment."

06/15/2004 - "A clinical prediction rule for pulmonary embolism is most helpful when it is used with subsequent evaluations such as ventilation-perfusion scanning, D-dimer testing, or computed tomography. "
04/01/2018 - "An elevated age-adjusted D-dimer value (age in years × 10 μg FEU/l) for patients at least 50 years old has been recommended as a better cut-off with adequate sensitivity and improved specificity for identifying pulmonary embolism compared with the conventional value. "
05/01/2009 - "The purpose of our study was to investigate whether D-dimer screening is being used effectively to determine the need for MDCT in diagnosing acute pulmonary embolism (PE) in emergency department patients. "
05/01/2011 - "Recently, a diagnostic strategy using a clinical decision rule, D-dimer testing and spiral computed tomography (CT) was found to be effective in the evaluation of patients with clinically suspected pulmonary embolism (PE). "
01/11/2006 - "A diagnostic management strategy using a simple clinical decision rule, D-dimer testing, and CT is effective in the evaluation and management of patients with clinically suspected pulmonary embolism. "

01/01/2020 - "Computed tomography pulmonary angiogram (CTPA) is widely considered the gold standard for diagnosis of pulmonary embolism (PE) with previous studies demonstrating high sensitivity and specificity. "
05/01/2019 - "CTPA is the gold standard investigation for evaluating suspected pulmonary embolism (PE) in the general population however is sometimes considered second line in pregnant and post-partum patients with a normal CXR due to its higher breast dose and the increased radio-sensitivity of breast tissue during this period. "
01/01/2010 - "In conclusion, DE-CTPA has potential advantages for evaluations of pulmonary embolism and regarding improved image noise, vessel contrast, and diagnostic confidence compared with single higher-kilovolt (peak) protocols."
01/01/2023 - "The present study was designed to evaluate the role of chest ultrasound in the diagnosis of acute pulmonary embolism (PE) and determine its accuracy using multi-detector CT-pulmonary angiography (MD-CTPA) as a gold standard technique for PE diagnosis. "
10/01/2023 - "MIP technique on CTPA may be helpful in diagnosing pulmonary embolism."

01/01/2020 - "Analyses were based on the double-blind, randomized PADIS-PE trial, which included 371 unprovoked pulmonary embolism patients initially treated for 6 months, successively randomized to receive an additional 18 months of warfarin or placebo, and subsequently followed-up for 2 years. "
07/01/2019 - "This was a post hoc analysis of the randomized, double-blind, placebo-controlled PADIS-PE trial that randomized patients with a first unprovoked pulmonary embolism (PE) initially treated during 6 months to receive an additional 18-month of warfarin vs. placebo. "
01/01/2018 - " were based on the double-blind randomised PADIS-PE trial, which included 371 patients with a first unprovoked pulmonary embolism initially treated during 6 months who were randomised to receive an additional 18 months of warfarin or placebo and followed up for 2 years after study treatment discontinuation. "
01/01/2011 - "Further familial study was performed, and the patient's older sister was revealed to have the same mutation; she was already taking warfarin due to diagnosed pulmonary thromboembolism. "
11/01/2022 - "Ultimately, after developing a pulmonary embolism, she accepted to be on warfarin. "

04/01/2019 - "Previous clinical trials have addressed that rivaroxaban is effective for the treatment of patients with pulmonary embolism (PE). "
11/26/2015 - "Rivaroxaban, particularly in the acute phase of pulmonary embolism, may be considered an effective and safe therapeutic choice even in elderly patients, a population less represented in clinical trials."
05/01/2019 - "Low-dose rivaroxaban was an effective treatment for pulmonary embolism in the elderly patient presented here."
04/02/2021 - "Efficacy of rivaroxaban for the treatment of Chinese patients with acute pulmonary embolism: A retrospective study."
05/01/2019 - "Efficacy of low-dose rivaroxaban in an 88-year-old female with pulmonary embolism: A case report."

08/01/2017 - "The use of enoxaparin is considered to be safe and effective for pulmonary embolism prophylaxis after pancreatic surgery."
06/01/2003 - "Following our study we can conclude that extended 3-month treatment with enoxaparin as monotherapy for symptomatic, acute pulmonary embolism is feasible and warrants further study in a large clinical trial."
01/01/1994 - "No clinically symptomatic pulmonary embolism was observed during the treatment or follow-up phase of this study in the group that received thirty milligrams of enoxaparin every twelve hours. "
10/25/2023 - "An unintentional administration of enoxaparin 900 mg occurred in a 73-year-old man with coronavirus disease 2019-related pulmonary embolism. "
05/01/2020 - "This report describes a case of enoxaparin-induced hepatotoxicity in a 61-year-old male diagnosed with pulmonary embolism. "

01/01/2008 - "Authors consider alteplase to be highly effective in the treatment of massive pulmonary embolism. "
12/01/1989 - "A case of pulmonary thromboembolism in a young woman three days status post-abdominal surgery is treated successfully with a low-dose infusion rate of tissue plasminogen activator (10 mg/hr over 10 h). "
01/01/2021 - "An accelerated thrombolytic regimen with alteplase 0.6 mg/kg (maximum of 50 mg) over 15 min for acute pulmonary embolism appeared be effective and safe in a case series of Vietnamese patients."
12/01/2018 - "This experience may help guide the design of a randomized controlled trial to determine the safety and efficacy of low-dose alteplase for submassive pulmonary embolism."
01/01/2008 - "[The efficacy of alteplase in pulmonary embolism treatment]."

10/01/1995 - "Thrombolytic agents have been used successfully to treat patients with massive pulmonary embolism and cardiorespiratory insufficiency, but experience with these drugs in pregnancy is limited. "
03/01/1993 - "Thrombolytic agents are widely used as first line treatment in severe acute pulmonary embolisms. "
01/01/2019 - "[Comparative efficacy of various thrombolytic agents in treatment of pulmonary embolism]."
11/01/2005 - "Efficacy of thrombolytic agents in the treatment of pulmonary embolism."
10/01/2017 - "In the current study, we evaluated the prognostic value of TRI in patients with moderate-high and high risk pulmonary embolism (PE) who were treated with thrombolytic agents. "

05/01/2012 - "While the primary therapy for most patients with a pulmonary embolism (PE) consists of anticoagulation, the efficacy of thrombolysis relative to standard therapy remains unclear. "
11/01/2017 - "The patient responded well to the therapy, and contrast-enhanced computed tomography showed nearly complete disappearance of the pulmonary embolism. "
12/01/2010 - "Accurate evaluation of venous system of lower limb by duplex scan is important in all cases of pulmonary embolism, the anticoagulation may be ineffective in preventing pulmonary embolism and the surgical repair is the mainstay of therapy of this pathology because it is safe and effective."
07/01/2006 - "ROBOT therapy results in a significant, rapid improvement in the hemodynamic situation and in a better outcome than conventional therapy in patients with acute massive pulmonary embolism."
09/01/2005 - "Thrombolytic and anticoagulation therapies are beneficial in keeping the balance between coagulation and fibrinolysis and protecting the functions of vascular endothelial cells in patients with pulmonary thromboembolism."

10/01/2020 - "Protocolized use of catheter-directed thrombolysis and echocardiography is highly effective in reversing acute right heart dysfunction in severe submassive pulmonary embolism patients."
05/14/2023 - "The Safety and Efficacy of Ultrasound-Accelerated Catheter-Directed Thrombolysis in Patients with Intermediate-High-Risk Pulmonary Embolism: Bo-NE-Experience."
04/04/2023 - "EKOSTM in Octogenarians: The Safety and Efficacy of Ultrasound-Accelerated Catheter-Directed Thrombolysis in Elderly Patients with Intermediate-High-Risk Pulmonary Embolism."
09/26/2019 - "The echocardiogram showed McConnell's sign suggesting a massive pulmonary embolism; the pulmonary angiography showed large thrombi in both branches of pulmonary artery, so a catheter-based treatment was performed with thromboaspiration and rt-PA administration, and a significant improvement of blood pressure, clinical condition and right ventricle function was observed. "
01/01/2018 - "Regarding "Catheter-directed, ultrasound-assisted thrombolysis is a safe and effective treatment for pulmonary embolism, even in high-risk patients"."

01/01/2019 - "The purpose of the present study is to evaluate the safety and efficacy of "low-dose" systemic thrombolytic therapy (TT) for treatment of patients with intermediate-high risk submassive pulmonary embolism (PE). "
01/01/2023 - "Recurrent High-Risk Pulmonary Thromboembolism Treated with Repeated Thrombolytic Therapy Could be Helpful for Certain Patients: A Case Report and Review of the Literature."
12/01/2018 - "Patients with sub-massive pulmonary embolism accompanied by right heart dysfunction who are treated with thrombolytic therapy likely will experience more rapid improvement in RV function and are less likely to progress to hemodynamic decompensation. "
06/18/2014 - "Thrombolytic therapy may be beneficial in the treatment of some patients with pulmonary embolism. "
12/01/2009 - "Acute massive pulmonary embolism with hemodynamic compromise treated successfully with thrombolytic therapy."

08/01/2014 - "It has been proven that the use of an inferior vena cava filter (IVCF) is effective in decreasing the incidence of pulmonary embolism (PE) in high-risk spinal surgery patients. "
09/15/2010 - "To evaluate the safety and efficacy of prophylactic inferior vena cava filter (IVCF) to prevent pulmonary embolism (PE) in high risk patients undergoing major complex spinal surgery. "
01/01/2009 - "Retrievable inferior vena cava filters (IVCFs) offer protection against pulmonary embolism during this high-risk period, when anticoagulation is discontinued, while avoiding potential long-term sequelae of a permanent IVCF. "
05/01/2008 - "A retrievable inferior vena cava filter, as an adjunct to chemical and mechanical prophylaxis, was a safe and effective means of reducing the acute risk of pulmonary embolism in this high-risk group of patients. "
11/01/2005 - "The OptEase permanent/retrievable vena cava filter can be safely and successfully retrieved up to 14 days in patients who no longer require inferior vena cava filter protection against pulmonary embolism."

04/01/2007 - "Open pulmonary embolectomy is the most effective treatment for acute massive pulmonary embolism. "
11/01/2001 - "Emergency surgical pulmonary embolectomy is a highly effective treatment for selected patients with pulmonary embolism. "
07/01/1991 - "Transesophageal echocardiography seems to be a very helpful technique to diagnose promptly massive pulmonary embolism and a very useful tool at the time of operation to guide the embolectomy."
02/01/1977 - "We present the findings in a patient with acute massive pulmonary embolism who underwent transvenous pulmonary embolectomy, with immediate and marked improvement in hemodynamic function and survival. "
01/01/2007 - "[Massive pulmonary embolism treated successfully with embolectomy following failed thrombolysis--the role of repeated spiral computerised tomography and echocardiography--a case report]."