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gamma-Glutamyl Hydrolase (Carboxypeptidase G2)

Catalyzes the hydrolysis of pteroylpolyglutamic acids in gamma linkage to pterolylmonoglutamic acid and free glutamic acid. EC 3.4.19.9.
Also Known As:
Carboxypeptidase G2; Carboxypeptidase G; Carboxypeptidase G1; Folacin Conjugase; Folate Hydrolyzing Enzyme; Folyl Poly-gamma-Glutamate Carboxypeptidase; Folyl Polyglutamate Cleavage Enzyme; Folylpolyglutamate Hydrolase; gamma Glutamyl Hydrolase; Conjugase; Folate Conjugase; Folyl Conjugate Synthetase; Pteroyl Polyglutamate Hydrolase
Networked: 126 relevant articles (2 outcomes, 8 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Goda, Sayed K: 5 articles (02/2020 - 12/2009)
2. Springer, Caroline J: 5 articles (11/2009 - 03/2002)
3. Bashraheel, Sara S: 4 articles (02/2020 - 01/2018)
4. Pui, Ching-Hon: 4 articles (05/2014 - 07/2002)
5. Friedlos, Frank: 4 articles (07/2008 - 03/2002)
6. Marais, Richard: 4 articles (07/2008 - 03/2002)
7. Begent, R H: 4 articles (03/2000 - 01/2000)
8. Sharma, S K: 4 articles (03/2000 - 01/2000)
9. Rashidi, Fatma B: 3 articles (04/2019 - 01/2018)
10. Hedley, Douglas: 3 articles (07/2008 - 06/2005)

Related Diseases

1. Lymphoma (Lymphomas)
2. Acute Kidney Injury (Acute Renal Failure)
3. Neoplasms (Cancer)
4. Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
5. Colorectal Neoplasms (Colorectal Cancer)

Related Drugs and Biologics

1. Methotrexate (Mexate)
2. glucarpidase
3. Enzymes
4. Folic Acid (Vitamin M)
5. Thymidylate Synthase
6. Prodrugs
7. folylpolyglutamate synthetase
8. Proteins (Proteins, Gene)
9. Reduced Folate Carrier Protein
10. Methylenetetrahydrofolate Reductase (NADPH2) (Methylenetetrahydrofolate Reductase)

Related Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Chemoradiotherapy
4. Ventriculoperitoneal Shunt
5. Adjuvant Chemotherapy