Protons (Proton)

Stable elementary particles having the smallest known positive charge, found in the nuclei of all elements. The proton mass is less than that of a neutron. A proton is the nucleus of the light hydrogen atom, i.e., the hydrogen ion.

Also Known As:

Networked: 7396 relevant articles (254 outcomes, 1233 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Li, Zuofeng: 45 articles (09/2015 - 11/2007)
2.	Sakurai, Hideyuki: 39 articles (11/2015 - 12/2009)
3.	Mizumoto, Masashi: 37 articles (11/2015 - 06/2007)
4.	Yock, Torunn I: 36 articles (01/2016 - 12/2004)
5.	Okumura, Toshiyuki: 36 articles (11/2015 - 03/2002)
6.	Tokuuye, Koichi: 35 articles (04/2014 - 04/2003)
7.	Sugahara, Shinji: 35 articles (04/2014 - 04/2003)
8.	Tarbell, Nancy J: 34 articles (01/2016 - 01/2004)
9.	Mendenhall, Nancy P: 34 articles (09/2015 - 12/2008)
10.	Mohan, Radhe: 34 articles (03/2015 - 07/2006)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2015 - "Protons offered the best sparing of small bowel and rectum and therefore could contribute to a significant reduction of acute and late toxicity in cervical cancer treatment." 01/01/1988 - "The proton magnetic resonance imaging contrast of experimental mammary tumors in rats has been dramatically improved. " 02/01/2014 - "In summary, protons were found to be significantly more effective in reducing the tumor volume than photons (P < 0.05). " 09/01/2013 - "He underwent the 3rd gross tumor removal at 11 months of age, followed by proton therapy, and now he remains disease-free for 3 yr without a significant neurocognitive dysfunction. " 03/01/2013 - "Use of high-energy protons at CNAO is a safe and effective means of treating a tumor located near critical normal structures."
2.	Melanoma (Melanoma, Malignant) 01/01/2010 - "Proton beam therapy (PBT) is effective in the treatment of iris melanoma. " 01/01/2007 - "Proton beam therapy is an effective treatment for cases of nonresectable iris melanoma. " 01/01/1995 - "Our aim is to answer whether or not the proton beam can provide useful treatment for cutaneous melanoma. " 08/01/1999 - "To compare the efficacy of iodine-125 (125I) and ruthenium-106 (106Ru) episcleral plaque radiation therapy and proton beam radiation therapy (PBRT) in the treatment of choroidal melanoma. " 07/01/2015 - "Fifteen choroidal melanoma patients treated with proton-beam therapy were enroled in the study. "
3.	Prostatic Neoplasms (Prostate Cancer) 06/01/2009 - "Proton radiation has proven effective in dose escalation for prostate cancer. " 01/01/2015 - "This study has demonstrated the potential of using an improved beam angle arrangement to better exploit the theoretical dosimetric benefits of proton therapy and provided insights of selecting quality beam angles for localized prostate cancer treatment." 01/01/2015 - "This study investigates potential gains of an improved beam angle arrangement compared to a conventional fixed gantry setup in intensity modulated proton therapy (IMPT) treatment for localized prostate cancer patients based on a proof of principle study. " 05/01/2008 - "The objective of this study was to evaluate the efficacy of proton magnetic resonance spectroscopy (1H-MRS) in the detection of prostate cancer. " 01/01/2015 - "Improved beam angle arrangement in intensity modulated proton therapy treatment planning for localized prostate cancer."
4.	Hepatocellular Carcinoma (Hepatoma) 04/01/1994 - "A new, effective, and safe therapeutic option using proton irradiation for hepatocellular carcinoma." 12/01/2009 - "The authors have shown proton beam therapy to be both safe and effective for the treatment of patients with hepatocellular carcinoma. " 12/01/2009 - "The authors have published a series of studies evaluating the safety and efficacy of proton beam therapy for the treatment of hepatocellular carcinoma in a variety of clinical settings. " 02/01/2010 - "To investigate the safety and efficacy of proton beam therapy (PBT) in patients with large hepatocellular carcinoma (HCC). " 11/01/2007 - "To investigate the safety and efficacy of proton beam therapy for aged patients with hepatocellular carcinoma (HCC). "
5.	Chordoma 10/01/2011 - "Given the high cost of proton facilities and improved techniques for other forms of radiation therapy, this article evaluates whether proton therapy is still superior to other radiation techniques in the treatment of chordomas." 08/01/2006 - "To assess the efficacy of definitive treatment of sacral chordoma by high-dose proton/photon-beam radiation therapy alone or combined with surgery. " 06/01/2014 - "Chordoma management is more widely studied with en bloc resection and adjuvant proton-beam therapy demonstrating improved progression-free survival and overall survival. " 04/01/2012 - "Multimodal surgery and proton therapy thus improved the chordoma treatment. " 01/01/2010 - "Proton therapy is the gold standard in the treatment of skull base chordomas. "

Related Drugs and Biologics

1.	Protons (Proton)
2.	Sodium
3.	N-acetylaspartate (N-acetyl aspartate)
4.	Ions
5.	Carbon
6.	Creatine
7.	Lactic Acid
8.	Helium
9.	bevacizumab
10.	gemcitabine

Related Therapies and Procedures

1.	Radiotherapy
2.	Drug Therapy (Chemotherapy)
3.	Brachytherapy
4.	Conformal Radiotherapy
5.	Particle Accelerators