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Protein C

A vitamin-K dependent zymogen present in the blood, which, upon activation by thrombin and thrombomodulin exerts anticoagulant properties by inactivating factors Va and VIIIa at the rate-limiting steps of thrombin formation.
Networked: 5278 relevant articles (168 outcomes, 597 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Griffin, John H: 63 articles (01/2021 - 06/2002)
2. Esmon, Charles T: 46 articles (01/2022 - 01/2002)
3. Levi, Marcel: 33 articles (11/2017 - 06/2003)
4. van der Poll, Tom: 31 articles (01/2022 - 06/2003)
5. Fernández, José A: 29 articles (01/2021 - 06/2002)
6. Zlokovic, Berislav V: 26 articles (01/2020 - 05/2003)
7. Rosing, Jan: 23 articles (01/2017 - 07/2002)
8. Matthay, Michael A: 21 articles (01/2021 - 04/2003)
9. Mosnier, Laurent O: 21 articles (12/2020 - 09/2004)
10. Grinnell, Brian W: 20 articles (01/2015 - 12/2002)

Related Diseases

1. Sepsis (Septicemia)
2. Septic Shock (Toxic Shock Syndrome)
3. Inflammation (Inflammations)
4. Hemorrhage
5. Protein C Deficiency

Related Drugs and Biologics

1. drotrecogin alfa activated (Xigris)
2. Anticoagulants
3. Protein S
4. Antithrombin III
5. Heparin (Liquaemin)
6. Antithrombins
7. Dacarbazine (DIC)
8. Surface-Active Agents (Surfactants)
9. Proteins (Proteins, Gene)
10. lipoprotein-associated coagulation inhibitor (TFPI)

Related Therapies and Procedures

1. Therapeutics
2. Resuscitation
3. Catheters
4. Artificial Respiration (Mechanical Ventilation)
5. Surgical Amputation (Amputations)