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Prostatitis

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Infiltration of inflammatory cells into the parenchyma of PROSTATE. The subtypes are classified by their varied laboratory analysis, clinical presentation and response to treatment.

Also Known As:

Acute Bacterial Prostatitis; Asymptomatic Inflammatory Prostatitis; Chronic Bacterial Prostatitis; Chronic Prostatitis with Chronic Pelvic Pain Syndrome; Acute Bacterial Prostatitides; Asymptomatic Inflammatory Prostatitides; Bacterial Prostatitides, Acute; Bacterial Prostatitides, Chronic; Bacterial Prostatitis, Acute; Bacterial Prostatitis, Chronic; Chronic Bacterial Prostatitides; Inflammatory Prostatitis, Asymptomatic; Prostatitides; Prostatitides, Chronic Bacterial

Networked: 1596 relevant articles (197 outcomes, 250 trials/studies)

Relationship Network

Disease Context: Research Results

Male Urogenital Diseases
- Male Genital Diseases
  - Prostatic Diseases: 365
    - Prostatitis: 1596

Related Diseases

1.	Pelvic Pain
2.	Prostatic Hyperplasia (Benign Prostatic Hyperplasia)
3.	Infection
4.	Pain (Aches)
5.	Prostatitis

Experts

1.	Nickel, J Curtis: 25 articles (08/2013 - 08/2002)
2.	Schaeffer, Anthony J: 20 articles (08/2015 - 08/2002)
3.	Shoskes, Daniel A: 14 articles (08/2013 - 08/2002)
4.	Naber, K G: 14 articles (11/2011 - 03/2000)
5.	Cho, Yong-Hyun: 12 articles (01/2014 - 06/2002)
6.	Weidner, W: 11 articles (12/2014 - 02/2000)
7.	Wagenlehner, F M E: 11 articles (03/2013 - 06/2003)
8.	Alexander, Richard B: 11 articles (09/2010 - 08/2002)
9.	Krieger, John N: 10 articles (11/2012 - 01/2002)
10.	Mondaini, Nicola: 9 articles (02/2014 - 12/2006)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Prostatitis:

1.	Anti-Bacterial Agents (Antibiotics)IBA 03/01/2014 - "Our meta-analysis reveals that antibiotics are not beneficial in the management of category III prostatitis. " 03/01/2014 - "To determine whether antibiotics are beneficial in the management of category III prostatitis. " 03/01/2014 - "Antibiotics are not beneficial in the management of category III prostatitis: a meta analysis." 12/01/1986 - "Although Cephem antibiotics are transferred to the prostatic fluid in relatively low levels, they are clinically effective for bacterial prostatitis. " 01/01/1980 - "Therefore, these antibiotics should be effective in the treatment of bacterial prostatitis caused by susceptible organisms. "
2.	Ciprofloxacin (Cipro)FDA LinkGeneric 08/01/2002 - "Our model implies that ciprofloxacin 500 mg twice daily for 28 days appears to be the most cost effective treatment for chronic bacterial prostatitis. " 08/01/2002 - "Twice daily ciprofloxacin @ 500 mg for 28 days proved to be the most cost effective treatment for chronic bacterial prostatitis. " 06/01/2001 - "Ciprofloxacin has been shown to be effective in the treatment of chronic bacterial prostatitis caused by Escherichia coli. " 09/01/2003 - "Tc-99m ciprofloxacin imaging is helpful in the differential diagnosis of prostatitis syndrome." 05/01/2015 - "The study included 50 patients with chronic prostatitis who showed hot uptake in seminal vesicles on Tc-99m ciprofloxacin imaging and eight patients who did not show hot uptake. "
3.	Ofloxacin (Levofloxacin)FDA LinkGeneric 04/01/2007 - "[Longqingpian combined with levofloxacin highly effective for type IIIA prostatitis]." 04/01/2007 - "To study the therapeutic efficacy of Longqingpian combined with Levofloxacin on Type IIIA prostatitis. " 01/01/2015 - "Levofloxacin appears to be an effective antibiotic for treating symptoms of chronic bacterial prostatitis. " 12/01/1993 - "In conclusion, ofloxacin was thought to be very useful for the treatment of acute and chronic prostatitis." 06/01/2010 - "To compare the safety and efficacy of levofloxacin 750 mg QD for 2 weeks or levofloxacin 750 mg QD for 3 weeks to levofloxacin 500 mg QD for 4 weeks in treating chronic bacterial prostatitis (CBP). "
4.	VitaprostIBA 03/01/2015 - "These results indicate that combination therapy including Vitaprost is effective in correcting blood flow and microcirculatory disorders of the prostate and can be utilized in the treatment of chronic infectious urethral prostatitis." 03/01/2006 - "We studied efficacy of a new cytomedine drug--vitaprost--in 98 patients with chronic abacterial prostatitis. " 03/01/2015 - "The aim of the study was to assess the effect of a combined preparation of Vitaprost on blood supply and microcirculation in the prostate gland in 35 patients with chronic infectious urethral prostatitis. " 11/01/2013 - "[Effectiveness of Vitaprost Plus in the treatment of patients with chronic bacterial prostatitis]." 07/01/2012 - "[Efficiency of vitaprost in patients with chronic prostatitis]."
5.	Prostate-Specific Antigen (Semenogelase)IBA 03/01/2005 - "The symptoms were improved by medication for prostatitis, and prostate-specific antigen (PSA) level of 22.6 ng/ml descreased to 9.9 ng/ml. It remained between 7.2 ng/ml and 9.9 ng/ml for 2 years. " 01/01/2013 - "The aim of the study was to compare the yield of mean platelet volume (MPV), total prostate specific antigen (tPSA), free prostate specific antigen (fPSA), f/t PSA ratio and complex prostate specific antigen (cPSA) in patients with prostatitis. " 10/01/2010 - "The objective of the present study was to evaluate the efficacy and tolerability of cranberry (Vaccinium macrocarpon) powder in men at risk of prostate disease with LUTS, elevated prostate-specific antigen (PSA), negative prostate biopsy and clinically confirmed chronic non-bacterial prostatitis. " 12/01/2013 - "It seems interesting to confirm or infirm these attitudes with a systematic review of the literature We performed a literature review using the words [prostatitis], [acute prostatitis], [prostate specific antigen], [PSA], in the MEDLINE, Pubmed and AMBASE database searching for articles in French or English published in the past 20 years. " 11/01/2013 - "All patients suffered from lower urinary tract symptoms and an increased prostate-specific antigen (PSA) level associated with a suspicious digital rectal examination (DRE); however, at biopsy, the results were negative for xanthogranulomatous prostatitis. "
6.	ZincIBA 06/01/2002 - "Our results suggest that the local application of zinc to the prostate may be a new treatment for chronic bacterial prostatitis at the point of its pathogenesis." 05/01/2004 - "To study the efficacy of biological organic zinc in the treatment of chronic bacterial prostatitis (CBP). " 10/01/2013 - "to investigate the efficacy of zinc supplementation in chronic prostatitis treatment. " 10/01/2013 - "The efficacy of zinc for treatment of chronic prostatitis." 01/01/2015 - "Further studies with larger sample sizes are needed to better illuminate the negative impact of chronic prostatitis on zinc concentrations."
7.	FluoroquinolonesIBA 01/01/2002 - "Fluoroquinolones are now most effective in management of acute or exacerbation of chronic bacterial prostatitis. " 10/01/2006 - "The high tissue/ serum ratio and the extended antibacterial spectrum suggests active concentration in the prostate which may translate into increased efficacy compared to group 2 and 3 fluoroquinolones in the treatment of chronic bacterial prostatitis." 01/01/2002 - "Fluoroquinolones are safe and effective in managing chronic bacterial prostatitis. " 02/01/2011 - "Fluoroquinolones are the preferred agents for treating bacterial causes of prostatitis and have demonstrated efficacy in some cases of chronic prostatitis when an organism has not been identified. " 05/01/1998 - "These results support earlier studies demonstrating that fluoroquinolones are a useful class of antimicrobials for the treatment of chronic bacterial prostatitis. "
8.	tamsulosin (Flomax)FDA LinkGeneric 01/01/2014 - "Addition of tamsulosin to the LVX regimen was beneficial for patients with bacterial prostatitis because tamsulosin could increase the maximal concentration of LVX in prostatic tissue. " 09/01/2012 - "Qianlieping Capsule chronic is effective for chronic non-bacterial prostatitis, and the combination of Qianlieping Capsule with tamsulosin produces even better effect than tamsulosin alone." 03/01/2008 - "The efficacy of tamsulosin in the treatment of chronic non-bacterial prostatitis was evaluated in a randomized clinical observation of 105 male outpatients conducted for 90 days. " 12/01/1999 - "Terazosine and tamsulosin in non bacterial prostatitis: a randomized placebo-controlled study." 09/01/2012 - "To investigate the clinical effects of Qianlieping Capsule combined with alpha-receptor blocker tamsulosin on chronic non-bacterial prostatitis (CNBP). "
9.	cerniltonIBA 11/01/1989 - "The pollen extract, Cernilton, is reported to be effective in the treatment of this condition and we present the results of an open trial with Cernilton in a group of 15 patients with chronic prostatitis and prostatodynia. " 11/01/1989 - "Cernilton was found to be effective in the treatment of chronic prostatitis and prostatodynia. " 01/01/2010 - "The trial of efficacy and safety of two doses of the drug cernilton in patients with chronic abacterial prostatitis made in the Research Institute of Urology and I.M. " 01/01/2010 - "[A comparative clinical randomized trial of cernilton efficacy and safety in patients with chronic abacterial prostatitis]." 01/01/2010 - "Cernilton is recommended as a medication of choice for treatment of patients with chronic abacterial prostatitis."
10.	prulifloxacinIBA 04/01/2011 - "In summary, prulifloxacin appears to be a promising agent for the treatment of bacterial prostatitis and traveller's diarrhoea." 01/01/2010 - "The purpose of this study was to compare the efficacy of a 14-day course of prulifloxacin 600 mg with standard antibiotic therapy for the treatment of chronic prostatitis due to Chlamydia trachomatis (Ct) infection. " 01/01/2010 - "Clinical and microbiological efficacy of prulifloxacin for the treatment of chronic bacterial prostatitis due to Chlamydia trachomatis infection: results from a prospective, randomized and open-label study." 02/01/2009 - "Prulifloxacin has been successfully tested in Phase III randomized, controlled trials including patients with acute exacerbations of chronic bronchitis, uncomplicated and complicated urinary tract infections, and chronic bacterial prostatitis. " 09/01/2009 - "Re: Serenoa repens associated with Urtica dioica (ProstaMEV) and curcumin and quercitin (FlogMEV) extracts are able to improve the efficacy of prulifloxacin in bacterial prostatitis patients: results from a prospective randomised study."

Therapies and Procedures

1.	Massage (Reflexology) 10/01/2001 - "In men with chronic prostatitis caused by Gram-negative or combined Gram-negative and -positive bacteria, the endotoxin levels in urine collected immediately after prostatic massage were significantly greater (P < 0.01) than in a midstream urine sample, and the concentration in the EPS was significantly higher (P < 0.05) than that in the control group. " 08/01/2009 - "In this study we prospectively evaluate the efficacy of examination of post-prostatic massage urine for prediction of asymptomatic prostatitis in biopsies. " 03/01/2008 - "National Institutes of Health Chronic Prostatitis Symptom Index scores, expressed prostatic massage test and urodynamic urethral pressure and urethral closure pressure tests were performed to evaluate clinical efficacy of the treatments. " 04/01/2006 - "To evaluate the efficacy of regular prostatic massage in combination with culture-specific antibiotic therapy for men with chronic prostatitis. " 09/01/2006 - "[Clinical trials of combined therapy of an oral Chinese medicine with massage for chronic nonbacterial prostatitis]."
2.	Aftercare (After-Treatment) 09/01/2005 - "The prostatitis symptoms and sexual dysfunction were improved obviously after treatment in the two groups, but compared with the control, more marked improvement was observed in the combined psychologic treatment group (P <0.01). " 01/01/1989 - "Antibiotic treatment of patients with non-bacterial prostatitis reduced symptoms but also changed the bacterial flora in urethral and prostatic secretion in such a way that uropathogens were found after treatment. " 01/01/2003 - "A clinical study evaluated the sperm count and motility in 36 patients with chronic prostatitis before and after treatment for 60 days. " 12/01/2014 - "The International Prostate Symptom Score (IPSS), National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI), and erectile function (EF) domain scores of the International Index of Erectile Function (IIEF) questionnaire were used to grade symptoms at baseline and 6 weeks after treatment. " 09/01/2014 - "The main outcome measure was the change in the mean total NIH-Chronic Prostatitis Symptom Index scores between the two groups from baseline to after treatment. "
3.	Transurethral Resection of Prostate (TURP) 06/01/1996 - "Transurethral microwave thermotherapy appears to be an effective, safe and durable treatment for some patients with nonbacterial prostatitis unresponsive to traditional therapy." 01/01/2015 - "TURP is an acceptable procedure in the treatment of refractory recurrent bacterial prostatitis. " 01/01/2015 - "To explore the outcome of transurethral resection of the prostate (TURP) in the treatment of refractory recurrent acute bacterial prostatitis. " 11/01/2013 - "The xanthogranulomatous prostatitis can be an incidental finding after TURP and it can simulate prostatic malignancy with PSA elevation. " 12/01/2004 - "Cooled transurethral microwave thermotherapy for intractable chronic prostatitis--results of a pilot study after 1 year."
4.	Enzyme Therapy 11/01/2008 - "A comparative trial of efficacy of magnetolaser therapy, enzyme treatment with longidase and their combination in chronic prostatitis has shown that these methods significantly relieve symptoms, normalize laboratory, urodynamic and immunological indices, reduce structural changes in prostatic parenchyma. " 11/01/1998 - "Comparative clinical data are presented on efficacy of transurethral vacuum drainage of the prostate in patients with obstructive chronic prostatitis in the absence of systemic enzyme therapy and under treatment with enzyme medicine bobenzyme (Mucos Pharma, Germany) having proteolytic activity. " 11/01/2008 - "[Magnetolaser and enzyme therapy in combined treatment of patients with chronic bacterial prostatitis]." 11/01/1998 - "[Systemic (vobenzyme preparation) and local enzyme therapy in transurethral drainage of the prostate in patients with obstructive forms of chronic prostatitis]." 05/01/2011 - "A pharmacological cost-effective analysis of systemic enzymotherapy combination with fluoroquinolone antibiotics in the treatment of chronic bacterial prostatitis showed cost-effect of such therapy: medical cost efficacy of the treatment of chronic bacterial prostatitis with antibiotic + vobenzim is 2 times higher than of antibiotic treatment only."
5.	Chinese Traditional Medicine (Traditional Chinese Medicine) 03/01/2012 - "By retrospectively reviewing the current status of traditional Chinese medicine (TCM) and Western medicine treatments of chronic nonbacterial prostatitis (CNP), the TCM understanding of its etiologies and pathogenesis, the therapeutic principles and the mechanisms of acupuncture treatment of CNP, the clinical study strategies of acupuncture treatment for CNP were further proposed, which could provide more scientific basis and support for the definite longer-term therapeutic efficacy of acupuncture treatment of CNP. " 06/01/2003 - "[Efficacy of traditional Chinese medicine and Western medicine in the treatment of Ureaplasma urealyticun and Chlamydia trachomatis infectious chronic prostatitis (report of 48 cases)]." 12/01/2014 - "Based on the NIH chronic prostatitis symptom index (NIH-CPSI), traditional Chinese medicine (TCM) syndrome score, and leukocyte count in the expressed prostatic secretion (EPS), we evaluated the results of treatment. " 09/01/2013 - "Acupuncture and Traditional Chinese Medicine for the management of a 35-year-old man with chronic prostatitis with chronic pelvic pain syndrome." 10/01/2006 - "Traditional chinese medicine for the treatment of chronic prostatitis in China: a systematic review and meta-analysis."