Synthetic Prostaglandins (Prostaglandin Analogues)

09/01/2011 - "Once-per-day monotherapy glaucoma medications, such as prostaglandin analogues, are effective in lowering IOP while maintaining patients' adherence. "
01/01/2015 - "The present study is a transverse cross-sectional epidemiological survey among glaucoma patients receiving therapy with prostaglandin analogs. "
06/15/2013 - "The paper represents a clinical prospective observational and interventional study within a period of 11 months (September 2011- August 2012), which includes 214 patients diagnosed with glaucoma, by clinical and paraclinical examination, and, who were administrated prostaglandin analogues. "
09/01/2011 - "Larger studies with longer follow-up are needed to assess long-term safety, efficacy, and tolerability compared with other prostaglandin analogs used for treating glaucoma."
01/01/2010 - "The purpose of the present study was to evaluate persistence with prostaglandin analogs among glaucoma patients in the first therapy year using a modification of a previously published technique. "

08/01/1987 - "As in the treatment of peptic ulcer disease prostaglandin-analogues are only effective in preventing NOSAC-induced peptic lesions when given in antisecretory doses."
01/01/1986 - "Controlled trials of prostaglandin analogues in peptic ulcer healing have failed to demonstrate any superiority to conventional treatment. "
06/01/1989 - "First, in doses lower than those required to decrease acid secretion, prostaglandin analogues retain cytoprotective properties but are no better than placebo in healing peptic ulcers. "
01/09/1989 - "[Prostaglandin analogues in the treatment of peptic ulcer disease]."
01/01/1989 - "However, these mechanisms may not be critical variables to the healing of ordinary peptic ulcers because synthetic prostaglandins which stimulate these defensive mechanisms, heal ordinary peptic ulcers with an effectiveness predicted from their antisecretory potential. "

07/01/1978 - "Several endoscopically controlled studies abroad have found PG analogs to be effective in both gastric and duodenal ulcer disease. "
10/01/1995 - "We conclude that these prostaglandin analogues are safe and effective duodenal ulcer healing agents. "
01/01/1989 - "Prostaglandin analogues heal both gastric ulcers and duodenal ulcers, mainly as a result of acid inhibition. "
01/01/2015 - "Prostaglandin analogs, firstly used in obstetrics and gynecology, are now widespread in both sexes, especially in the treatment of gastric and duodenal ulcers, glaucoma, etc. Therefore, we tried to highlight the effects of repeated administration of Cloprostenol and CIPG isopropyl ester (both prostaglandin F2α analogs) for the male gonad. "
10/01/1995 - "We conducted a clinical trial to compare the efficacy and safety profile of two prostaglandin analogues, enprostil (35 micrograms twice daily) and misoprostol (200 micrograms four times daily) in the treatment of acute duodenal ulcers in 214 patients. "

03/01/1987 - "Orally administered prostaglandin analogues have been helpful in some patients who failed to heal with standard ulcer treatment and in smokers, who usually do not heal as well as nonsmokers. "
09/01/1998 - "Gastroprotective drugs such as prostaglandin analogs and prostaglandin inducers improve the quality of ulcer healing and reduce future recurrence. "
03/01/1991 - "[Prostaglandin analogs in ulcer therapy]."
01/01/1990 - "The expectation that prostaglandin analogues would improve the ulcer healing abilities of other agents by combining mucosal protection with decreased acid secretion has been proved unwarranted. "
04/17/1989 - "[Prostaglandin analogues in ulcer disease]."

01/01/2013 - "The effect of prostaglandin analogs on the biomechanical properties and central thickness of the cornea of patients with open-angle glaucoma: a 3-year study on 108 eyes."
08/01/2011 - "The effect of prostaglandin analogues on central corneal thickness of patients with chronic open-angle glaucoma: a 2-year study on 129 eyes."
01/01/2015 - "Decreased keratocyte density and central corneal thickness in primary open-angle glaucoma patients undergoing treatment with topical prostaglandin analogues."
01/01/2013 - "To evaluate the effect of prostaglandin analogs (PGAs) on the biomechanical properties (corneal hysteresis [CH], corneal resistance factor [CRF]) and central corneal thickness (CCT) of patients with open-angle glaucoma. "
01/01/2013 - "In recent years, prostaglandin analogs have become the first-line agents for treating open angle glaucoma. "