Propantheline (Propantheline Bromide)

A muscarinic antagonist used as an antispasmodic, in rhinitis, in urinary incontinence, and in the treatment of ulcers. At high doses it has nicotinic effects resulting in neuromuscular blocking.

Also Known As:

Networked: 91 relevant articles (4 outcomes, 16 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Elad, Sharon: 1 article (11/2013)
2.	Jensen, Siri Beier: 1 article (11/2013)
3.	Ariyawardana, Anura: 1 article (11/2013)
4.	Hovan, Allan: 1 article (11/2013)
5.	Barasch, Andrei: 1 article (11/2013)
6.	Yarom, Noam: 1 article (11/2013)
7.	Bowen, Joanne: 1 article (11/2013)
8.	Zadik, Yehuda: 1 article (11/2013)
9.	Lalla, Rajesh V: 1 article (11/2013)
10.	Jarvis, Virginia: 1 article (11/2013)

Related Diseases

1.	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 10/01/1989 - "We conclude that irritable bowel syndrome is a chronic relapsing disorder and that treatment with a combination of ispaghula husk and propantheline is effective, both in relieving symptoms and in the maintenance of remission." 10/01/1989 - "To examine the long-term management of irritable bowel syndrome we conducted a two-part controlled therapeutic trial on 28 patients who had recovered completely after four to six weeks of treatment with ispaghula husk and propantheline. " 04/01/1987 - "[Multicenter study on the effectiveness and tolerance of a bromazepam + propantheline combination in patients with irritable bowel syndrome]."
2.	Vasovagal Syncope 01/01/1997 - "It was concluded from this study that propantheline bromide is highly effective in preventing neurocardiogenic syncope. " 01/01/1997 - "Since cholinergic tone is important in the efferent part of the neurocardiogenic reflex, we investigated the pharmacodynamics and efficacy of propantheline bromide in preventing neurocardiogenic syncope. " 01/01/1997 - "Clinical efficacy of propantheline bromide in neurocardiogenic syncope: pharmacodynamic implications." 01/01/1997 - "In addition, propantheline bromide's effectiveness is more than would be expected by prevention of cardioinhibition in neurocardiogenic syncope and would support a role for direct cholinergic control of vascular tone."
3.	Abnormal Reflex (Hyperreflexia) 08/01/1980 - "Cystometric response to propantheline in detrusor hyperreflexia: therapeutic implications." 05/01/1986 - "Our results indicate that oxybutynin is more effective than propantheline in the treatment of detrusor hyperreflexia in patients with multiple sclerosis." 05/01/1986 - "Oxybutynin versus propantheline in patients with multiple sclerosis and detrusor hyperreflexia."
4.	Mucositis 08/01/1993 - "Mucositis was less frequent (2 of 6 vs 5 of 6) and less severe (p = 0.05) in the propantheline arm. " 08/01/1993 - "Propantheline is effective in reducing the incidence and severity of mucositis in patients receiving high-dose etoposide." 08/01/1993 - "Propantheline prevention of mucositis from etoposide."
5.	Multiple Sclerosis 05/01/1986 - "Our results indicate that oxybutynin is more effective than propantheline in the treatment of detrusor hyperreflexia in patients with multiple sclerosis." 05/01/1986 - "Oxybutynin versus propantheline in patients with multiple sclerosis and detrusor hyperreflexia."

Related Drugs and Biologics

1.	oxybutynin (Tavor)
2.	Psyllium (Metamucil)
3.	Etoposide (VP 16)
4.	amylopectin sulfate
5.	Cimetidine (Biomet)
6.	Propantheline (Propantheline Bromide)
7.	tolterodine (Detrol)
8.	methantheline (Banthine)
9.	Cholinergic Antagonists (Anticholinergics)
10.	Ranitidine (Zantac)

Related Therapies and Procedures

1.	Catheters
2.	Cryotherapy (Therapy, Cold)
3.	Condoms (Condom)
4.	Radiotherapy
5.	Ligation