Pronase

09/01/2014 - "Compared with the control group, the pronase group showed significantly decreased thickness of mucus (P < 0.001), increased depth of biopsy (P < 0.001), improved anatomical orientation (P = 0.010), and improved overall diagnostic assessment (P = 0.011) in the second biopsied specimen following endoscopic flushing. "
06/01/2012 - "Using pronase 20 minutes before endoscopy significantly improved endoscopic visualization and decreased the frequency of water flushing."
09/01/2014 - "Endoscopic flushing with pronase not only improved the depth of biopsy but also the anatomical orientation and overall diagnostic adequacy. "
09/01/2014 - "This study assessed whether endoscopic flushing with pronase improves the quality of gastric biopsy. "
09/01/2014 - "Pronase can be recommended for flushing during EGD to improve the quantity and quality of biopsy."

10/01/1995 - "The IHA, which used a pronase pretreatment and the H222 monoclonal antibody, was performed on archival tumor specimens of 25 patients. "
04/15/1986 - "Our results have shown that binding of tumor cells by non-activated macrophages was Ca2+ and temperature dependent; had a requirement for a Pronase-sensitive structure on macrophage surface membranes; was saturable; and was 2-3X less than that observed for activated macrophages. "
01/01/1982 - "Tumor homogenates, from which the nuclear fraction was removed, and the mitochondrial fractions of the host livers were digested with pronase P. "
11/01/1977 - "acnes produced inhibition of tumor growth, but crude cell walls and cell walls treated with Pronase had no effect. "
01/01/1969 - "[Procedures for the determination of the total neuraminic acid content of erythocytes and tumor cells, as well as in the use of pronase in tissue culture]."

02/01/2002 - "In cryptococcosis, pronase treatment of serum has reduced false positives and false negatives, and improved reproducibility of titres. "
10/01/1992 - "Our results show that (i) during the screening, concordance among the three tests was 97%; (ii) the use of pronase enhanced both the sensitivities and specificities of the Pastorex Cryptococcus test; (iii) titers agreed for 67% of the cerebrospinal fluid samples and 60% of the serum samples; and (iv) cryptococcosis was detected equally well with Pastorex Cryptococcus and with the other tests, whatever the infecting serotype (A, B, or D). "
11/01/1988 - "Cryptococcal antigen titers of 70 cerebrospinal fluid and 57 serum specimens from patients suspected of having cryptococcosis were determined both before and after treatment with pronase. "
08/01/1993 - "High detection rates of cryptococcal antigen in pulmonary cryptococcosis by Eiken latex agglutination test with pronase pretreatment."

03/01/1988 - "In the following experiments, glycopeptides were isolated from the pronase digests of breast carcinoma tissue. "
04/01/1986 - "On the other hand, the binding sites on carcinoma cells are resistant to trypsin but can be removed with Pronase. "
06/01/1983 - "The pronase-hydrolysates exhibited a differential cytocidal activity to normal diploid fibroblasts (WI38), their SV40-transformants (VA13) and carcinoma cells (A549) of human lung origin as was observed for the intact antibiotics. "
01/01/1985 - "Whereas no differences in cell yield or CFE were found between the enzyme cocktail studies (0.5% trypsin vs. 0.05% pronase), the cell yield and the CFE from the clone D carcinomas were significantly less than that found with the 0.5% trypsin (the cell yield and CFE from clone A tumors were identical for 0.5% trypsin or enzyme cocktail). "
08/01/1984 - "The pronase-treated fraction gave better antitumor activity to both ascites and solid type tumor of Ehrlich carcinoma or Sarcoma 180. "

05/23/2015 - "Additive Effect of Pronase on the Eradication Rate of First-Line Therapy for Helicobacter pylori Infection."
07/01/2011 - "[The effects of pronase on drugs concentrations for treatment of Helicobacter pylori infection in gastric tissue]."
01/21/2007 - "Neither pronase nor NAC produces any obvious interference with the CLO test for the identification of H pylori infection."
10/01/1985 - "Since the proportion of 80S ribosomes that were resistant to pronase digestion also increased after infection, these data suggest that the accumulated 80S ribosomes may be in the form of initiation complexes. "
03/01/1976 - "Virus DNA was isolated from I M-NaCl-SDS-pronase supernatant fluids from 24 h after infection. "