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Fenofibrate (CiL)

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An antilipemic agent which reduces both CHOLESTEROL and TRIGLYCERIDES in the blood.

Also Known As:

CiL; Lipidil; Tricor; AbZ Brand of Procetofen; Abbott Brand of Procetofen; Aliud Brand of Procetofen; Antara Micronized Procetofen; Anto Brand of Procetofen; Apo-Feno-Micro; Apo-Fenofibrate; Apotex Brand of Procetofen; Azupharma Brand of Procetofen; Bouchara Brand of Procetofen; Controlip; Fenobeta; Fenofanton; Fenofibrat AL; Fenofibrat AZU; Fenofibrat AbZ; Fenofibrat FPh; Fenofibrat Heumann; Fenofibrat Hexal; Fenofibrat Stada; Fenofibrat-ratiopharm; Fournier Brand of Procetofen; Fénofibrate Debat; Fénofibrate MSD; GNR-Pharma Brand of Procetofen; Gate Brand of Procetofen; Gen-Fenofibrate; Genpharm Brand of Procetofen; Heumann Brand of Procetofen; Hexal Brand of Procetofen; Knoll Brand of Procetofen; LF-178; Lichtenstein Brand of Procetofen; Lipanthyl; Lipantil; Liparison; Lipidil-Ter; Livesan; Lofibra; MTW Brand of Procetofen; MTW-Fenofibrat; Merck dura Brand of Procetofen; Normalip; Novartis Brand of Procetofen; Novo-Fenofibrate; Novopharm Brand of Procetofen; Nu-Fenofibrate; Nu-Pharm Brand of Procetofen; PMS-Fenofibrate Micro; Pharmascience Brand of Procetofen; Phenofibrate; Procetofene; Q-Pharm Brand of Procetofen; Reliant Brand of Procetofen; Schering-Plough Brand of Procetofen; Secalip; Stadapharm Brand of Procetofen; Supralip; United Drug Brand of Procetofen; betapharm Brand of Procetofen; ct-Arzneimittel Brand of Procetofen; durafenat; fenofibrat von ct; ratiopharm Brand of Procetofen; AZU, Fenofibrat; Apo Feno Micro; Apo Fenofibrate; Debat, Fénofibrate; Fenofibrat ratiopharm; GNR Pharma Brand of Procetofen; Gen Fenofibrate; Heumann, Fenofibrat; Hexal, Fenofibrat; LF 178; LF178; Lipidil Ter; MTW Fenofibrat; Micronized Procetofen, Antara; Novo Fenofibrate; Nu Fenofibrate; Nu Pharm Brand of Procetofen; PMS Fenofibrate Micro; Procetofen Reliant Brand; Procetofen, Antara Micronized; Q Pharm Brand of Procetofen; Schering Plough Brand of Procetofen; Stada, Fenofibrat; ct Arzneimittel Brand of Procetofen; Procetofen; Propanoic acid, 2-(4-(4-chlorobenzoyl)phenoxy)-2-methyl-, 1-methylethyl ester

Networked: 1173 relevant articles (129 outcomes, 303 trials/studies)

Relationship Network

Drug Context: Research Results

Organic Chemicals: 58

Experts

1.	Keech, Anthony C: 17 articles (09/2015 - 11/2006)
2.	Krysiak, Robert: 14 articles (10/2015 - 10/2004)
3.	Farnier, Michel: 12 articles (07/2012 - 04/2006)
4.	Elisaf, Moses S: 11 articles (01/2015 - 08/2003)
5.	Watts, Gerald F: 10 articles (09/2015 - 12/2002)
6.	Bordet, Régis: 10 articles (01/2015 - 07/2003)
7.	Staels, Bart: 10 articles (03/2014 - 12/2002)
8.	Jenkins, Alicia J: 9 articles (09/2015 - 02/2012)
9.	Ansquer, Jean-Claude: 9 articles (10/2014 - 04/2003)
10.	Elisaf, Moses: 9 articles (08/2014 - 01/2002)

Related Diseases

1.	Hyperlipidemias (Hyperlipidemia) 04/01/2006 - "The polymorphism of human IFABP gene in hyperlipidemia is related with the therapeutic efficacy of fenofibrate, and the T54T IFABP genotype may have strong negative effect on such efficacy." 01/01/1989 - "The first well-controlled studies of fenofibrate in the United States indicate that the drug is safe and effective for the treatment of type IIa and type IIb hyperlipidemia. " 03/01/2013 - "Lipid lowering studies in Triton induced hyperlipidemia rat model demonstrated higher lipid lowering ability for fenofibrate lipospheres compared to the commercial product and plain drug." 01/01/1989 - "Recent trials have investigated the usefulness of fenofibrate, alone and in combination with other lipid-lowering therapies, in the treatment of hyperlipidemia. " 09/25/2015 - "Fenofibrate is a potent agonist of PPARα and is used in the treatment of hyperlipidemia. "
2.	Dyslipidemias (Dyslipidemia) 08/01/2011 - "Fenofibrate monotherapy tended to improve TG and HDL-C levels to a significantly greater extent than statin monotherapy in primary dyslipidemia, whereas statin monotherapy decreased LDL-C and TC levels to a significantly greater extent than fenofibrate monotherapy. " 12/01/2002 - "Fenofibrate is effective in reducing levels of TG, TC, and LDL-C, and increasing levels of HDL-C in patients with dyslipidemias. " 11/01/2004 - "Fenofibrate at 300 mg per day is effective and safe in treating Thai patients with dyslipidemia." 10/01/1994 - "In comparison to the standard formulation, micronised fenofibrate thus provides improved efficacy in the control of dyslipidemia and the prevention of CHD." 06/01/2011 - "A trial of statin + fenofibrate in people with IR/MS and/or T2DM who also have significant dyslipidemia is needed."
3.	Hypertriglyceridemia 05/01/1998 - "It is also effective in patients with isolated hypertriglyceridemia and, although less potent than fenofibrate at reducing TRL and increasing HDL-C, it has a greater impact on the atherogenic risk ratios such as LDL-C:HDL-C. " 06/01/2004 - "Fenofibrate is an effective, well-tolerated treatment for hypertriglyceridemia associated with HLS." 06/01/2005 - "The aim of this study was to assess the food-related efficacy of a new formulation of micronized fenofibrate coated on inert microgranules (FF-muG) for the treatment of hypertriglyceridemia in patients exhibiting the metabolic syndrome. " 08/01/2007 - "Fenofibrate therapy ameliorates fasting and postprandial lipoproteinemia, oxidative stress, and the inflammatory response in subjects with hypertriglyceridemia and the metabolic syndrome." 03/01/2006 - "In the present study, 45 subjects with hypertriglyceridemia were recruited to receive treatment with fenofibrate (200 mg/d). "
4.	Diabetic Retinopathy (Retinopathy, Diabetic) 06/01/2015 - "The ACCORD-Eye study reported a statistically significant reduction in diabetic retinopathy progression in patients treated with fenofibrate and statin combination therapy compared to statin therapy alone. " 05/01/2012 - "Although recent clinical trials have demonstrated that fenofibrate is effective for treating diabetic retinopathy, the mechanism of this beneficial effect remains unclear. " 01/01/2013 - "Fenofibrate: a new treatment for diabetic retinopathy. " 11/01/2011 - "A consistent feature of fibrate clinical trials is the specific benefit of these agents in dyslipidaemic patients and the improvement in diabetic retinopathy with fenofibrate. " 03/01/2011 - "A consistent feature of fibrate clinical trials is the specific benefit of these agents in dyslipidaemic patients and the improvement in diabetic retinopathy with fenofibrate. "
5.	Atherosclerosis 07/01/2011 - "The aim of this study was to analyze, using homo- and heterozygous PPARα-deficient mice, the consequences of quantitative variations of PPARα gene levels and their response to the synthetic PPARα agonist fenofibrate on NASH and atherosclerosis in apoE2-KI mice. " 02/01/2008 - "As reported by the Fenofibrate Intervention and Event Lowering in Diabetes study, fenofibrate treatment has also been associated with microvascular benefits in patients with type 2 diabetes, which is consistent with preliminary evidence from the Diabetes Atherosclerosis Intervention Study. " 03/01/2005 - "Fenofibrate reduces progression to microalbuminuria over 3 years in a placebo-controlled study in type 2 diabetes: results from the Diabetes Atherosclerosis Intervention Study (DAIS)." 01/01/2002 - "Results of the initial cardiovascular morbidity/mortality outcomes study with fenofibrate (known as DAIS [Diabetes Atherosclerosis Intervention Study]) were encouraging vis-à-vis slowing of atherosclerotic progression in the coronary vasculature of type II diabetics. " 05/01/2000 - "To study the mechanism of regression of atherosclerosis (AS) by lipanthyl. "

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