Precancerous Conditions

01/01/1992 - "These findings suggest that vitamin A, C, and E supplementation is effective in reducing abnormalities in cell kinetics that may indicate a precancerous condition. "
03/15/1991 - "Therapeutic trials of vitamin A and related compounds have demonstrated activity in several cancerous and precancerous conditions. "
12/01/1985 - "The high prevalence of oral and esophageal precancerous conditions and low blood levels of riboflavin, carotene, and vitamin A observed in the surveyed population, as well as the existing evidence on the possible protective effect of these nutrients in carcinogenesis, provide an opportunity and a justification for the chemopreventive trial, with the regression of observed precancerous lesions as the end point of the study."

04/01/2012 - "The objective of this paper is to provide an improved technique, which can assist oncopathologists in correct screening of oral precancerous conditions specially oral submucous fibrosis (OSF) with significant accuracy on the basis of collagen fibres in the sub-epithelial connective tissue. "
08/01/2004 - "This study aimed to assess the association of such genotype with the risk of OSCC and oral submucous fibrosis (OSF), which is a precancerous condition that exhibits excessive collagen production and etiologically links to areca use. "
01/01/2013 - "Oral submucous fibrosis (OSF), a precancerous condition, is characterized by abnormal accumulation of collagen fibers in oral submucosa. "
05/01/2012 - "Oral submucous fibrosis (OSF) is a precancerous condition in which there is excessive deposition of collagen in connective tissue. "
09/01/2013 - "The nut alkaloids have been shown experimentally to result in stimulation of collagen synthesis by fibroblasts in vitro, which can induce precancerous conditions. "

01/01/1989 - "After 16 weeks of supplementation, erythrocyte folate levels of subjects with esophageal dysplasia were improved but remained significantly lower than those of normal supplemented subjects, targeting folic acid as a nutrient of particular interest in this precancerous condition."
09/01/2002 - "Observational studies evaluating the association between folate and risk for colorectal and cervical cancers or precancerous conditions have produced conflicting results, and clinical trial data are needed to confirm a cause-and-effect relationship. "

01/01/2015 - "Combination RNA interference on genes of CTGF and TIMP-1 is superior to that of single RNA interference, and this could be a contribution for prevention of precancerous condition."
01/01/2015 - "In this study, influence caused by expression plasmids of connective tissue growth factor (CTGF) and tissue inhibitor of metalloproteinase-1 (TIMP-1) short hairpin RNA (shRNA) on mRNA expression of CTGF,TIMP-1,procol-α1 and PCIII in hepatic tissue with hepatic fibrosis, a precancerous condition, in rats is analyzed. "

05/01/2014 - "In this study, the efficacy of glucosamine to attenuate dextran sodium sulfate (DSS)-induced colitis, a precancerous condition for CRC, was evaluated. "

05/01/2014 - "In this study, the efficacy of glucosamine to attenuate dextran sodium sulfate (DSS)-induced colitis, a precancerous condition for CRC, was evaluated. "

05/01/2014 - "In this study, the efficacy of glucosamine to attenuate dextran sodium sulfate (DSS)-induced colitis, a precancerous condition for CRC, was evaluated. "

03/01/2008 - "It is believed that the combination of such imaging techniques with novel biomarkers of dysplasia will greatly assist in identifying precancerous conditions such as Barrett's esophagus (BE). "
01/01/2004 - "pylori decreases gastric cancer risk, using preneoplastic conditions as surrogate markers. "
10/01/2005 - "This trial tested whether an intervention to reduce these risk factors in patients with Barrett esophagus, a preneoplastic condition for esophageal adenocarcinoma, could reduce biomarkers of cellular proliferation and, by inference, the risk of neoplastic progression. "
01/01/2005 - "To investigate the feasibility of combining several serum markers into a valid serum screening tool for gastric cancer, we performed a study evaluating the association between gastric cancer and precancerous conditions and a blood test for gastric acidity (the blood quininium resin test [QRT]) combined with serum pepsinogen levels. "
02/01/2008 - "The aim of this study was to investigate the potential of biomarkers pepsinogen I (PGI), pepsinogen II (PGII), their ratio (PG I:II), as well as gastrin 17 for screening of precancerous conditions and corpus predominant gastritis. "

03/01/2006 - "Noninvasive testing is both possible and practical by using pepsinogen assays for the identification of the precancerous condition of moderate to severe corpus atrophy in North American Hispanic patients."
01/01/2005 - "To investigate the feasibility of combining several serum markers into a valid serum screening tool for gastric cancer, we performed a study evaluating the association between gastric cancer and precancerous conditions and a blood test for gastric acidity (the blood quininium resin test [QRT]) combined with serum pepsinogen levels. "
02/01/2008 - "The aim of this study was to investigate the potential of biomarkers pepsinogen I (PGI), pepsinogen II (PGII), their ratio (PG I:II), as well as gastrin 17 for screening of precancerous conditions and corpus predominant gastritis. "

01/01/2010 - "However, regional DNA hypermethylation on C-type CpG islands has already accumulated in such non-cancerous renal tissues, suggesting that, from the viewpoint of altered DNA methylation, the presence of precancerous conditions can be recognized even in the kidney. "
07/15/2006 - "Regional DNA hypermethylation may be associated with renal tumorigenesis from a precancerous condition to malignant progression and become a predictor of patient prognosis."
07/23/2002 - "Overexpression of DNMT3b4, a splice variant of DNMT3b lacking conserved methyltransferase motifs IX and X, significantly correlated with DNA hypomethylation on pericentromeric satellite regions in precancerous conditions and HCCs (P = 0.0001). "
09/23/1971 - "[DNA content of precancerous conditions of the skin. "
04/02/2008 - "It has been known for a long time that DNA hypomethylation occurs in many human cancers and precancerous conditions. "

10/15/2006 - "Immunotherapy offers a therapeutic strategy to counteract these effects with promising results seen particularly in precancerous conditions and early tumours. "
01/01/2012 - "Especially, we speculate that hypomethylation of gene promoters may play roles in inducing immunity and inflammation disorders in precancerous conditions, which may provide hints for improving epigenetic therapy and immunotherapy of cancer."

08/01/1990 - "This present study shows that laser flow cytometry can detect changes in the genome of lesions known to become malignant when the histological degree of transformation still indicates only a preneoplastic condition. "
11/01/1992 - "Though in various fields the research is merely in initial phase (holography, caries-treatment, photodynamic therapy, etc.), the lasers are becoming an indispensable (treatment of precancerous conditions, hemophilic patients, diseases of the oral mucosa, etc.). "
01/01/2014 - "[Early gastric cancer and precancerous conditions diagnostics with confocal laser endomicroscopy]."
11/01/1992 - "The surgical lasers are applied in the treatment of teeth, in preprosthetic surgery, salivary gland diseases, precancerous conditions, tumour surgery and in the surgery of hemophilic patients, respectively. "
10/01/1991 - "Because the field of laser biotechnology is still rapidly emerging, it is very likely that new lasers and modifications of existing ones will improve our ability to treat skin cancer and precancerous conditions."

09/01/2007 - "Closure of the temporary diverting ileostomy in patients with inflammatory bowel disease or any other inflammatory conditions within the peritoneal cavity are at the increased risk of complications than in those with malignant diseases or precancerous conditions. "
09/01/2007 - "The aim of this study was designed to assess the results of the closure of the protective ileostomy in the group of patients' operated on for inflammatory bowel disease and other inflammatory conditions with inflammatory exudate and to compare them with those who underwent surgery for uncomplicated colorectal cancer and precancerous conditions. "

08/01/1992 - "The aim of this study was to determine whether changes in serum free radicals may be useful for the early detection of precancerous conditions in the rat colon after treatment with a direct carcinogen (N-Methyl-N'-Nitro-N-Nitrosoguanidine, MNNG) and a secondary bile acid (deoxycholic acid, DCA) as a tumor promoter. "

08/01/1989 - "Intragastric nitrosation has been implicated in the pathogenesis of gastric cancer and in precancerous conditions such as pernicious anaemia and the post-gastrectomy state. "
03/01/1980 - "Menetrier's disease may be a precancerous condition of the association may be a coincidence, but it would still seem preferable to propose surgical treatment and "rather a total gastrectomy". "
10/01/1995 - "As gastric adenoma with SEA had been considered to be a precancerous condition but not normally an indication for gastrectomy, we devised an operative strategy of laparotomy and thoracotomy. "
01/01/1988 - "In order to determine an histological high-risk group, we chose cases with preneoplastic conditions (60 CAG, 10 biopsies of gastric remnants, 3 flat adenomas and 55 gastrectomies by cancer or ulcer). "
01/15/2000 - "This novel assay also might be used to monitor the circulating amount of tumor-associated antigen after gastrectomy and provide information regarding recurrence or metastasis, as well as for screening elderly patients who have no indications for endoscopy and those with precancerous conditions. "