Postgastrectomy Syndromes

Sequelae of gastrectomy from the second week after operation on. Include recurrent or anastomotic ulcer, postprandial syndromes (DUMPING SYNDROME and late postprandial hypoglycemia), disordered bowel action, and nutritional deficiencies.

Also Known As:

Networked: 44 relevant articles (1 outcomes, 4 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Stomach Neoplasms (Stomach Cancer)
2.	Ulcer
3.	Gastritis
4.	Peptic Ulcer (Peptic Ulcers)
5.	Pain (Aches)

Experts

1.	Nakada, Koji: 6 articles (01/2016 - 06/2014)
2.	Kodera, Yasuhiro: 4 articles (01/2016 - 01/2015)
3.	Takahashi, Masazumi: 4 articles (01/2016 - 01/2015)
4.	Kawashima, Yoshiyuki: 3 articles (10/2015 - 06/2014)
5.	Terashima, Masanori: 3 articles (07/2015 - 06/2014)
6.	Ikeda, Masami: 3 articles (04/2015 - 04/2003)
7.	Urushihara, Takashi: 2 articles (01/2016 - 06/2014)
8.	Tanabe, Kazuaki: 2 articles (01/2016 - 06/2014)
9.	Kawahira, Hiroshi: 2 articles (10/2015 - 06/2014)
10.	Hiki, Naoki: 2 articles (10/2015 - 09/2005)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Postgastrectomy Syndromes:

1.	GhrelinIBA 12/01/2013 - "In the patients with a baseline GSRS score of ≥2, rikkunshito significantly improved the symptoms of postgastrectomy syndrome, and its effect was possibly independent of the plasma ghrelin levels."
2.	Serotonin (5 Hydroxytryptamine)IBA 02/01/1968 - "[Effect of serotonin inactivators on the tryptophan serum level in patients with postgastrectomy syndromes]." 01/01/2004 - "To test the hypothesis that the changes in ileal smooth muscle contractility accompanying postgastrectomy syndromes are agonist-specific, we investigated the effects of potassium chloride (KCl), carbachol, substance P (SP), and serotonin on ileal smooth muscle contractility after total gastrectomy in rats. "
3.	Bile Acids and Salts (Bile Acids)IBA 09/01/1980 - "The hypothesis that reflux of upper intestinal content, particularly of bile acids (BA), is responsible for a unique postgastrectomy syndrome, alkaline reflux gastritis, was tested on 28 occasions in 21 postoperative patients (14 symptomatic patients, 7 controls). " 01/01/1979 - "Eight patients with severe postgastrectomy syndromes for predominantly bile reflux gastritis were examined by quantification of bile acids in the gastric remnant before and after a standardized liquid meal. "
4.	VitaminsIBA 11/01/1973 - "[Vitamin metabolism in patients with ulcer disease and in postgastrectomy syndrome]."
5.	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 12/01/1967 - "[The vitamin B 12 content, and protein composition of the blood serum in patients with postgastrectomy syndromes]."
6.	Tryptophan (L-Tryptophan)FDA Link 02/01/1968 - "[Effect of serotonin inactivators on the tryptophan serum level in patients with postgastrectomy syndromes]."
7.	Substance PIBA 01/01/2004 - "To test the hypothesis that the changes in ileal smooth muscle contractility accompanying postgastrectomy syndromes are agonist-specific, we investigated the effects of potassium chloride (KCl), carbachol, substance P (SP), and serotonin on ileal smooth muscle contractility after total gastrectomy in rats. "
8.	Growth Hormone (Somatotropin)IBA 01/28/1956 - "[Postgastrectomy syndrome; spectacular results of somatotropin]."
9.	Protein HydrolysatesIBA 06/01/1973 - "[Free amino acids in the blood serum in patients with postgastrectomy syndrome in connection with parenteral feeding with protein hydrolysates]."
10.	Potassium ChlorideFDA LinkGeneric 01/01/2004 - "To test the hypothesis that the changes in ileal smooth muscle contractility accompanying postgastrectomy syndromes are agonist-specific, we investigated the effects of potassium chloride (KCl), carbachol, substance P (SP), and serotonin on ileal smooth muscle contractility after total gastrectomy in rats. "

Therapies and Procedures

1.	Gastrectomy 04/01/2015 - "Long-term quality-of-life comparison of total gastrectomy and proximal gastrectomy by postgastrectomy syndrome assessment scale (PGSAS-45): a nationwide multi-institutional study." 10/01/2015 - "Recently, a self-report assessment instrument, the Postgastrectomy Syndrome Assessment Scale-45 (PGSAS-45), was compiled to evaluate symptoms, the living status and the quality of life of patients who have undergone gastrectomy. " 01/01/2015 - "Using the PGSAS-45, a multi-institutional survey was conducted to determine the prevalence of postgastrectomy syndrome and its impact on everyday life among patients who underwent various types of gastrectomy. " 12/01/2011 - "Total gastrectomy leads to decreased quality of life, which is characterized by different symptoms of the postgastrectomy syndrome. " 10/01/2011 - "The first postgastrectomy syndrome was noted not long after the first gastrectomy was performed. "
2.	Gastroenterostomy 11/07/2013 - "Efferent loop syndrome is a very rare postgastrectomy syndrome that can occur following Billroth-II or Roux-en-Y reconstruction. " 09/01/1970 - "[Postgastrectomy syndrome in the Billroth II. Polya-Hoffmeister technic]." 04/01/1961 - "A case of interposition for postgastrectomy syndrome following the Billroth II operation." 08/01/1984 - "A study of 118 patients, operated on with Billroth II gastrectomy for peptic disease and affected by postgastrectomy syndromes, was carried out. " 01/01/2016 - "We evaluated symptoms of postgastrectomy syndrome (PGS) and QOL by means of a newly developed integrated questionnaire, the Postgastrectomy Syndrome Assessment Scale-45 (PGSAS-45), and compared PPG with Billroth-I distal gastrectomy (DGBI). "
3.	Vagotomy 01/01/1983 - "When vagotomy was added to antrectomy and gastroduodenostomy it seemed to increase the risk of developing serious (Visick 3u and 4) postgastrectomy syndromes; 12% after antrectomy and vagotomy versus 3% after antrectomy alone. "
4.	Parenteral Nutrition 06/01/1973 - "[Free amino acids in the blood serum in patients with postgastrectomy syndrome in connection with parenteral feeding with protein hydrolysates]."
5.	Lymph Node Excision (Lymph Node Dissection) 12/01/1999 - "For the purpose of prevention of postgastrectomy syndrome and a less invasive and yet curative oncological resection, a purely laparoscopic pylorus-preserving gastrectomy with extraperigastric lymphadenectomy was performed for a patient with early gastric cancer located in the middle third of the stomach. "