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Polymyxin B (Aerosporin)

A mixture of polymyxins B1 and B2, obtained from BACILLUS POLYMYXA strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin B is used for treatment of infections with gram-negative bacteria, but may be neurotoxic and nephrotoxic.
Also Known As:
Aerosporin; Polymyxin B Sulfate
Networked: 1374 relevant articles (156 outcomes, 192 trials/studies)

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Drug Context: Research Results

Experts

1. Li, Jian: 42 articles (01/2022 - 12/2007)
2. Nation, Roger L: 29 articles (01/2022 - 12/2007)
3. Zavascki, Alexandre P: 21 articles (12/2021 - 11/2008)
4. Velkov, Tony: 20 articles (01/2022 - 06/2013)
5. Ronco, Claudio: 18 articles (12/2022 - 01/2005)
6. Tam, Vincent H: 18 articles (11/2020 - 09/2005)
7. Nakamura, Tsukasa: 16 articles (12/2011 - 05/2002)
8. Koide, Hikaru: 15 articles (09/2011 - 05/2002)
9. Wang, Jiping: 14 articles (01/2022 - 03/2013)
10. Tsuji, Brian T: 14 articles (01/2020 - 01/2015)

Related Diseases

1. Septic Shock (Toxic Shock Syndrome)
2. Infections
3. Sepsis (Septicemia)
4. Endotoxemia
5. Critical Illness (Critically Ill)

Related Drugs and Biologics

1. Endotoxins
2. Anti-Bacterial Agents (Antibiotics)
3. Neomycin
4. Colistin (Coly-Mycin)
5. Bacitracin (Baci-Rx)
6. Polymyxins (Polymyxin)
7. Carbapenems (Carbapenem Antibiotics)
8. Trimethoprim (Proloprim)
9. Cytokines
10. Lipopolysaccharides

Related Therapies and Procedures

1. Hemoperfusion
2. Therapeutics
3. Hemodiafiltration
4. Continuous Renal Replacement Therapy
5. Drug Therapy (Chemotherapy)