Poly G

05/06/2014 - "In a cohort of 22 patients, we detect poly-G variants in 91% of tumors. "
05/06/2014 - "Here we report that a simple PCR-based assay interrogating somatic variation in hypermutable polyguanine (poly-G) repeats can provide a rapid and reliable assessment of mitotic history and clonal architecture in human cancer. "
01/01/2004 - "Besides these changes there were two tumors which showed a novel insertion of A within this poly(G) repeat making a change in 9 samples (R4, 36%). "
01/01/2004 - "Seven of the 25 tumors showed deletion of a G within eight poly(G) repeats. "
10/09/2003 - "This activity led us to the investigation of the possible antitumoral properties of poly-G-ODNs in an established CD8-dependent tumor eradication model. "

05/23/2023 - "[Poly-G for tumor matched samples chronicles the evolution of human colorectal cancer]."
10/01/2003 - "In contrast, four (50%) of the eight microsatellite instability-high sporadic colorectal carcinomas had a mutation in the poly (G) 8 tract. "
04/01/1998 - "We examined mutations of BAX in MI+ cancers of various organs and found frameshift mutations at the poly(G)8 tract in 5 of 15 (33%) gastric cancers, 3 of 26 (12%) endometrial cancers, and 9 of 22 (41 %) colorectal cancers. "
05/15/1997 - "We found frameshift mutations in the poly(G)8 tract of IGFIIR in eight tumors, all of which were MI+: 4 of 26 (15%) MI+ endometrial cancers, 3 of 12 (25%) MI+ gastric cancers, and 1 of 18 (6%) MI+ colorectal cancers. "
05/23/2023 - "Objective: To analyze poly-guanine (poly-G) genotypes and construct the phylogenetic tree of colorectal cancer (CRC) and provide an efficient and convenient method for the study of intra-tumor heterogeneity and tumor metastasis pathway. "

05/23/2023 - "Based on the difference of Poly-G genotypes between paired samples, the distance matrix was calculated, and the phylogenetic tree was constructed to clarify the tumor metastasis pathway. "
05/06/2014 - "We generate poly-G mutation profiles of spatially separated samples from primary carcinomas and matched metastases to build well-supported phylogenetic trees that illuminate individual patients' path of metastatic progression. "
05/23/2023 - "Objective: To analyze poly-guanine (poly-G) genotypes and construct the phylogenetic tree of colorectal cancer (CRC) and provide an efficient and convenient method for the study of intra-tumor heterogeneity and tumor metastasis pathway. "

05/06/2014 - "We use poly-G repeat genotyping to study the evolution of colon carcinoma. "
05/06/2014 - "Finally, we show that poly-G mutations can be found in other cancers than colon carcinoma. "
05/06/2014 - "We generate poly-G mutation profiles of spatially separated samples from primary carcinomas and matched metastases to build well-supported phylogenetic trees that illuminate individual patients' path of metastatic progression. "

07/15/2002 - "Poly-G was found in pgtA in all (24 out of 24) of the isolates from patients with disseminated gonococcal infection (DGI). "
07/15/2002 - "However, in many other GC, pgtA lacks the poly-G and is expressed constitutively without Pv. Furthermore, by screening a large number of clinical isolates, a significant correlation was observed between the presence of poly-G in pgtA and the dissemination of GC infection. "
01/01/1968 - "Pulse-labeled 3H-RNA, isolated from cultures of Escherichia coli B at various times after T7 infection, hybridized exclusively with the poly G-binding strand H, indicating that only this strand is transcribed in vivo. "
01/01/1980 - "poly(C) intensified the infection development and increased the animal death rate, while poly(G) . "
06/01/1984 - "Combined administration of poly (G) X poly (C) and virazole to mice 1-2 or 24 hours after infection with tick-borne encephalitis virus provided a much more pronounced decrease in the death rate of the animals than the use of the interferonogen alone. "