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Staphylococcal Pneumonia

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Pneumonia caused by infections with bacteria of the genus STAPHYLOCOCCUS, usually with STAPHYLOCOCCUS AUREUS.

Also Known As:

Pneumonia, Staphylococcal; Staphylococcus Aureus Pneumonia; Pneumonia, Staphylococcus Aureus; Pneumonias, Staphylococcal; Pneumonias, Staphylococcus Aureus; Staphylococcal Pneumonias; Staphylococcus Aureus Pneumonias

Networked: 130 relevant articles (6 outcomes, 3 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Pneumonia (Pneumonitis)
2.	Osteomyelitis
3.	Urinary Tract Infections (Urinary Tract Infection)
4.	Meningitis
5.	Infection

Experts

1.	Dong, Jing: 6 articles (04/2013 - 11/2011)
2.	Bubeck Wardenburg, Juliane: 6 articles (01/2010 - 02/2007)
3.	Zhang, Yu: 5 articles (04/2013 - 11/2011)
4.	Deng, Xuming: 4 articles (01/2013 - 11/2011)
5.	Li, Hongen: 4 articles (01/2013 - 11/2011)
6.	Wang, Jianfeng: 4 articles (01/2013 - 11/2011)
7.	Niu, Xiaodi: 4 articles (01/2013 - 11/2011)
8.	Otto, Michael: 3 articles (01/2016 - 12/2007)
9.	Natanson, Charles: 3 articles (11/2015 - 07/2003)
10.	Schlievert, Patrick M: 3 articles (01/2014 - 01/2007)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Staphylococcal Pneumonia:

1.	Penicillins (Penicillin)FDA Link 07/01/1961 - "CAse 502: the management of penicillin resistant staphylococcal pneumonia with dimethoxyphenly penicillin." 11/01/1944 - "Report on a Case of Staphylococcal Pneumonia with Staphylococcal Septicaemia: Treated with Penicillin." 01/01/1984 - "However, as first choice therapy it should be reserved for cases of penicillin allergy, or cases of strongly suspected staphylococcal pneumonia. " 08/01/1965 - "[Changes in the organs following the use of sulfadimezin, penicillin and erythromycin in staphylococcal pneumonia. " 12/09/1950 - "Fulminating staphylococcal pneumonia treated with massive doses of chloramphenicol and penicillin."
2.	Gentamicins (Gentamicin)FDA LinkGeneric 01/01/1996 - "[Effectiveness of the treatment of staphylococcal pneumonia with liposomal gentamicin in an experiment]." 12/01/1990 - "We analyzed the general condition of patients, etiology, mortality, prognosis and management and reached to the conclusion that (1) gram-negative bacilli become major pathogen in replace of Gram-positive staphylococcus aureus in 1980s, but staphylococcus aureus pneumonia is still a serious disease (2) the prognosis of the patient is related to underlying disease, nourishment and complication (3) at present, Cephalosporin V is most effective in Gram-positive cocci pneumonia and Gentamycin or Cephalosporin V, in Gram-negative bacilli pneumonia. " 04/01/2002 - "Flucloxacillin or dicloxacillin should be added if staphylococcal pneumonia is suspected, and gentamicin or other specific therapy if gram-negative pneumonia is suspected; a third-generation cephalosporin plus intravenous erythromycin is recommended as initial therapy for severe cases. "
3.	AntigensIBA 06/01/1984 - "[Comparative study of the indices of immunological reactivity and of the HLA antigen system in staphylococcal pneumonia in young children]." 12/01/1982 - "Although the majority of patients did not have detectable free staphylococcal antigen, it was found in three patients with staphylococcal pneumonia. " 02/18/2008 - "Active immunization with a mutant form of Hla (Hla(H35L)), which cannot form pores, generates antigen-specific immunoglobulin G responses and affords protection against staphylococcal pneumonia. "
4.	Intravenous Immunoglobulins (IVIG)FDA Link 10/01/1993 - "The efficacy of IVIG was tested in an experimental model of staphylococcal pneumonia, using both an MRSA clinical isolate and reference strain Cowan III, in mice immunosuppressed with cyclophosphamide. "
5.	Immunoglobulin G (IgG)IBA 02/18/2008 - "Active immunization with a mutant form of Hla (Hla(H35L)), which cannot form pores, generates antigen-specific immunoglobulin G responses and affords protection against staphylococcal pneumonia. "
6.	Fibronectins (Fibronectin)IBA 10/01/1990 - "Intraabdominal administration of fibronectin also was effective for staphylococcal pneumonia in rat. "
7.	Cyclophosphamide (Cytoxan)FDA LinkGeneric 10/01/1993 - "The efficacy of IVIG was tested in an experimental model of staphylococcal pneumonia, using both an MRSA clinical isolate and reference strain Cowan III, in mice immunosuppressed with cyclophosphamide. "
8.	Monoclonal AntibodiesIBA 07/01/2009 - "Anti-alpha-hemolysin monoclonal antibodies mediate protection against Staphylococcus aureus pneumonia."
9.	biapenem (L 627)IBA 07/01/1994 - "L-627 was effective in cases with osteomyelitis due to Staphylococcus aureus, pneumonia and purulent meningitis due to penicillin-resistant Streptococcus pneumoniae, and urinary tract infections due to Enterococcus faecalis, Escherichia coli, or Pseudomonas aeruginosa. "
10.	LatexIBA 02/05/2015 - "Electron microscopic studies such as Field emission scanning electron microscopic (Fe-SEM) and Transmission electron microscope (TEM) reveals that synthesized AgNPs are spherical in shape with the size range between 5 and 30 nm. Further, crude latex aqueous extract and synthesized AgNPs were evaluated against different bacterial pathogens such as Bacillus cereus, Enterococci sp, Shigella sp, Pseudomonas aeruginosa, Klebsiella pneumonia, Staphylococcus aureus and Escherichia coli. "

Therapies and Procedures

1.	Artificial Respiration (Mechanical Ventilation) 11/01/2009 - "The brain computed tomogram was not remarkable, but Glasgow Coma Scale score remained at 8. Mechanical ventilation was required for rapidly progressive hypoxaemia related to Staphylococcus aureus pneumonia and septicaemia. " 04/01/1991 - "We report a patient with fulminant Staphylococcus aureus pneumonia complicated by chronic BPF formation which prevented weaning from mechanical ventilation due to severe air leak. " 01/01/1981 - "Staphylococcus aureus pneumonia as a complication during treatment of neurosurgical patients with mechanical ventilation." 01/01/1981 - "During 1978 a high incidence of Staphylococcus aureus pneumonia (11/54) was found in patients treated with mechanical hyperventilation for cerebral lesions, compared to other patients on mechanical ventilation in the same ward (1/148). " 09/01/2014 - "Managing respiratory failure and acute respiratory distress syndrome secondary to PVL-expressing Staphylococcus aureus pneumonia and its associated lung necrosis with mechanical ventilation is challenging. "
2.	Extracorporeal Membrane Oxygenation (ECMO) 05/01/2005 - "PATIENT 2 was a 13-yr-old male treated with venoarterial ECMO for cardiopulmonary failure from necrotizing staphylococcal pneumonia. " 11/01/2010 - "Panton-Valentine leukocidin expressing Staphylococcus aureus pneumonia managed with extracorporeal membrane oxygenation: experience and outcome."
3.	Transplantation (Transplant Recipients) 07/01/1975 - "Subacute staphylococcal pneumonia in a renal transplant recipient." 02/01/1982 - "Nontoxic staphylococcal pneumonia with empyema in a renal transplant recipient." 07/01/1975 - "Thus, staphylococcal pneumonia may complicate the differential diagnosis of pulmonary infection in transplant recipients."
4.	Suction (Suction Drainage) 06/15/1961 - "[The value of suction drainage in the treatment of abscessing staphylococcal pneumonias in infancy]." 02/01/1964 - "[COMBINED SUCTION DRAINAGE AND HIGH PRESSURE RESPIRATION IN PROTRACTED TENSION PNEUMOTHORAX AFTER SUPPURATIVE STAPHYLOCOCCAL PNEUMONIA]."
5.	Immunotherapy 01/01/2011 - "An evaluation of the emerging vaccines and immunotherapy against staphylococcal pneumonia in children." 10/01/1993 - "Passive local immunotherapy of experimental staphylococcal pneumonia with human intravenous immunoglobulin."