of Sheep Progressive Interstitial Pneumonia (Maedi)

Chronic respiratory disease caused by the VISNA-MAEDI VIRUS. It was formerly believed to be identical with jaagsiekte (PULMONARY ADENOMATOSIS, OVINE) but is now recognized as a separate entity.

Also Known As:

Networked: 70 relevant articles (2 outcomes, 2 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Visna
2.	Encephalitis (Encephalitis, Rasmussen)
3.	Arthritis (Polyarthritis)
4.	Virus Diseases (Viral Diseases)
5.	Pneumonia (Pneumonitis)

Experts

1.	Peterhans, E: 3 articles (11/2001 - 04/2000)
2.	Polledo, L: 2 articles (04/2019 - 04/2013)
3.	Preziuso, S: 2 articles (04/2019 - 01/2003)
4.	Rossi, G: 2 articles (04/2019 - 01/2003)
5.	Minguijón, E: 2 articles (02/2015 - 04/2013)
6.	Amorena, B: 2 articles (04/2013 - 07/2009)
7.	Crespo, H: 2 articles (04/2013 - 07/2009)
8.	Glaria, I: 2 articles (04/2013 - 07/2009)
9.	Luján, L: 2 articles (04/2013 - 07/2009)
10.	Ramírez, H: 2 articles (04/2013 - 07/2009)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to of Sheep Progressive Interstitial Pneumonia:

1.	AntigensIBA 10/01/2011 - "Three animals (1.12%), out of 267 samples tested, were found to be seropositive to the visna-maedi antigens in both tests. " 01/01/2003 - "The results suggest that (i) MVV causes heterogeneous lesions in homogeneously reared ewes, (ii) MVV p28 antigen is detectable not only in inflammed target organs, but also in pulmonary lymph nodes, spleen and bone marrow, and (iii) immunohistochemistry and PCR are useful methods for Maedi-Visna diagnosis in suspected cases, also when serological tests are negative." 01/01/1993 - "In the present paper antigen preparation is described to be used for diagnostics of Maedi-Visna disease by immunodiffusion test (IDT). " 01/01/1993 - "[Preparation of precipitation antigens for the diagnosis of Maedi-Visna]." 04/01/1988 - "Sera from 74 sheep culled from one flock on the basis of performance and response to immunological tests for paratuberculosis or maedi visna were used to evaluate the serological response to a sonicated antigen of Mycobacterium paratuberculosis by crossed immunoelectrophoresis. "
2.	EnzymesIBA 04/01/1995 - "[Comparative studies of maedi-visna diagnosis: immunodiffusion test, enzyme immunoassay, immunoblot]." 04/01/1998 - "Enzyme-linked immunosorbent assay (ELISA) and agar gel immunodiffusion (AGID) are the most widely used serological tests for Maedi-Visna diagnostics. " 10/01/1990 - "We report the efficacy of an anionic detergent, sodium dodecyl sulfate (SDS) for preparing maedi-visna antigens for an indirect enzyme-linked immunosorbent assay (i-ELISA). "
3.	Peptides (Polypeptides)IBA 04/15/2013 - "ENV-TM ELISAs based on peptides 126M1 (Se: 82%; Sp: 95%) and 126M2 0,65 0.77 (Se: 68%; Sp: 88%) detected preferentially caprine arthritis encephalitis (CAEV, type B) and visna/maedi (VMV, type A) virus infections respectively, which may help to perform a preliminary CAEV vs. VMV-like typing of the flock. " 11/29/2022 - "Polypeptide variation encoded by the ovine transmembrane protein 154 gene (TMEM154) is associated with susceptibility to ovine lentivirus, the causative agent of Ovine Progressive Pneumonia (OPP) and Visna/Maedi. "
4.	ImmunosorbentsIBA 04/01/1998 - "Enzyme-linked immunosorbent assay (ELISA) and agar gel immunodiffusion (AGID) are the most widely used serological tests for Maedi-Visna diagnostics. " 10/01/1990 - "We report the efficacy of an anionic detergent, sodium dodecyl sulfate (SDS) for preparing maedi-visna antigens for an indirect enzyme-linked immunosorbent assay (i-ELISA). "
5.	Sodium Dodecyl Sulfate (Sodium Lauryl Sulfate)IBA 10/01/1990 - "We report the efficacy of an anionic detergent, sodium dodecyl sulfate (SDS) for preparing maedi-visna antigens for an indirect enzyme-linked immunosorbent assay (i-ELISA). "
6.	Detergents (Detergent)IBA 10/01/1990 - "We report the efficacy of an anionic detergent, sodium dodecyl sulfate (SDS) for preparing maedi-visna antigens for an indirect enzyme-linked immunosorbent assay (i-ELISA). "
7.	DNA (Deoxyribonucleic Acid)IBA 06/03/2011 - "Pairwise DNA distance and phylogenetic analyses revealed that all SRLV sequences obtained from sheep clustered tightly with prototypical Maedi visna sequences from America. " 05/01/2006 - "Maedi-visna proviral DNA sequences were detected in renal and lung tissue samples from these nine sheep by PCR, and the specificity of the amplified products was further verified by DNA sequencing. " 04/01/2000 - "The detection of proviral DNA by semi-nested polymerase chain reaction and phylogenetic analysis of Czech Maedi-Visna isolates based on gag gene sequences." 12/01/1975 - "Hybridization studies with [3H]-cDNA of progressive pneumonia, maedi and visna viruses demonstrate that lung DNA from sheep afflicted with progressive interstitial pneumonia possesses virus-related sequences not present in normal sheep lung DNA." 08/01/1972 - "Properties of maedi nucleic acid and the presence of ribonucleic acid- and deoxyribonucleic acid-dependent deoxyribonucleic acid polymerase in the virions."
8.	Complementary DNA (cDNA)IBA 12/01/1975 - "Hybridization studies with [3H]-cDNA of progressive pneumonia, maedi and visna viruses demonstrate that lung DNA from sheep afflicted with progressive interstitial pneumonia possesses virus-related sequences not present in normal sheep lung DNA." 10/01/1985 - "A recently isolated Israeli retrovirus from a sheep with maedi-visna was compared with other retroviruses, using cDNA-RNA hybridization in solution. "
9.	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 08/15/2006 - "Previous studies with the closely related maedi visna lentivirus have indicated that viral transcription is dependent upon the AP-1 transcription factor. "
10.	Transcription Factors (Transcription Factor)IBA 08/15/2006 - "Previous studies with the closely related maedi visna lentivirus have indicated that viral transcription is dependent upon the AP-1 transcription factor. "