HOME PRODUCTS SERVICES COMPANY CONTACT FAQ

Aspiration Pneumonia

Subscribe to New Research on Aspiration Pneumonia

A type of lung inflammation resulting from the aspiration of food, liquid, or gastric contents into the upper RESPIRATORY TRACT.

Also Known As:

Pneumonia, Aspiration; Gastric Acid Aspiration Syndrome; Mendelson Syndrome; Mendelson's Syndrome; Acid Aspiration Syndromes; Aspiration Pneumonias; Mendelsons Syndrome; Pneumonias, Aspiration; Syndrome, Acid Aspiration; Syndrome, Mendelson; Syndrome, Mendelson's; Syndromes, Acid Aspiration; Acid Aspiration Syndrome

Networked: 801 relevant articles (48 outcomes, 55 trials/studies)

Relationship Network

Disease Context: Research Results

Respiratory Tract Diseases: 445
- Lung Diseases: 12525
  - Pneumonia: 26841
    - Aspiration Pneumonia: 801
      - Lipid Pneumonia: 26
- Respiratory Tract Infections: 7395
  - Pneumonia: 26841
    - Aspiration Pneumonia: 801
      - Lipid Pneumonia: 26

Related Diseases

1.	Pneumonia (Pneumonitis)
2.	Lung Abscess
3.	Deglutition Disorders (Dysphagia)
4.	Infection
5.	Stroke (Strokes)

Experts

1.	Arai, Hiroyuki: 7 articles (01/2010 - 07/2003)
2.	Ebihara, Takae: 5 articles (03/2015 - 07/2003)
3.	Ebihara, Satoru: 4 articles (03/2015 - 09/2006)
4.	Yamaya, Mutsuo: 4 articles (03/2015 - 01/2002)
5.	Song, Ho-Young: 4 articles (03/2010 - 12/2007)
6.	Shin, Ji Hoon: 4 articles (03/2010 - 12/2007)
7.	Monnet, Eric: 3 articles (06/2014 - 11/2002)
8.	Hirota, Kazuyoshi: 3 articles (12/2012 - 10/2005)
9.	Raoult, Didier: 3 articles (01/2012 - 11/2003)
10.	Kim, Jin Hyoung: 3 articles (10/2009 - 12/2007)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Aspiration Pneumonia:

1.	Anti-Bacterial Agents (Antibiotics)IBA 01/01/2009 - "The use of antibiotics effective against anaerobic bacteria may be necessary for patients with potentially fatal aspiration pneumonia. " 09/01/1999 - "Intravenous antibiotics were started for aspiration pneumonia and his neurological symptoms gradually improved. " 06/29/2015 - "They both needed intubation and anticonvulsive therapy and acquired an aspiration pneumonia, which was treated with antibiotics. " 11/01/2014 - "A detailed examination revealed aspiration pneumonia, which was resolved with a course of antibiotics. " 01/01/2014 - "The diagnostic yield decreased in patients who had received antibiotics or patients with suspected aspiration pneumonia. "
2.	Clindamycin (Cleocin)FDA LinkGeneric 02/01/2012 - "gingivalis-aspiration pneumonia, but more so if clindamycin alone is used. " 04/01/2005 - "Reappraisal of clindamycin IV monotherapy for treatment of mild-to-moderate aspiration pneumonia in elderly patients." 03/01/1979 - "Clindamycin in treatment of aspiration pneumonia in children." 02/01/2012 - "Aerosolized clindamycin is superior to aerosolized dexamethasone or clindamycin-dexamethasone combination in the treatment of severe Porphyromonas gingivalis aspiration pneumonia in an experimental murine model." 04/01/2005 - "Clindamycin therapy for mild-to-moderate aspiration pneumonia is clinically effective, and provides economic advantages as compared to SBT/ABPC or PAPM/BP therapy."
3.	Cimetidine (Biomet)FDA LinkGeneric 06/01/1983 - "[Efficacy of cimetidine in the prevention of aspiration pneumonia in paediatric anaesthesia]." 05/01/1984 - "The use of cimetidine, an H2-receptor antagonist, to minimize the complications of acid aspiration pneumonia is reviewed. " 10/20/1983 - "[Effectiveness of cimetidine in the prevention of aspiration pneumonia in obstetrics]." 08/01/1983 - "Rectal cimetidine proved to be the more effective drug for prophylaxis of acid aspiration syndrome in paediatric anaesthesia." 10/01/1982 - "Preoperative prophylactic use of Cimetidine can be a useful method to reduce the frequency of Mendelson's syndrome without disadvantages."
4.	Ranitidine (Zantac)FDA LinkGeneric 02/01/1996 - "It is concluded that a single oral dose of ranitidine 150 mg is effective against the acid aspiration syndrome 60 min after administration." 02/01/1996 - "The efficacy and optimum time of administration of ranitidine in the prevention of the acid aspiration syndrome." 07/01/1984 - "Ranitidine and single-dose antacid therapy as prophylaxis against acid aspiration syndrome in obstetric practice." 10/03/1983 - "[Use of ranitidine - an H2 receptor antagonist - for the prevention of Mendelson's syndrome]." 02/01/1982 - "Oral ranitidine for prophylaxis against Mendelson's syndrome."
5.	C-Reactive ProteinIBA 11/01/1999 - "In addition, the following markers were examined to evaluate the efficacy of the surgery: score of aspiration pneumonia, body mass index, total protein, albumin, hematocrit, WBC count, C-reactive protein, erythrocyte sedimentation rate, and the Barthel Index, an indicator of daily activity. " 12/01/2013 - "C-reactive protein as a prognostic factor in elderly patients with aspiration pneumonia." 01/01/2013 - "No correlation was observed between the serum SP-A and plasma C-reactive protein concentrations in dogs with aspiration pneumonia and BTLI. " 08/01/1997 - "Value of C-reactive protein in the detection of bacterial contamination at the time of presentation in drug-induced aspiration pneumonia." 07/01/2015 - "From the first day of stay the patient suffered hyperthermia to 39,0° C° The diagnosis of the aspiration pneumonia was determined by radiological signs, bronchoscopy and inflammatory blood markers, C-reactive protein, leukocytosis. "
6.	sultamicillin (ampicillin-sulbactam)FDA LinkGeneric 05/01/2013 - "She was initially treated for aspiration pneumonia with ampicillin/sulbactam. " 01/01/2013 - "All patients received prophylactic intravenous ampicillin-sulbactam for 72 hours to reduce the risk of aspiration pneumonia. " 01/01/2007 - "In comparative clinical trials, ampicillin/sulbactam has proved to be a significant drug in the therapeutic armamentarium for lower respiratory tract infections and aspiration pneumonia, gynaecological/obstetrical infections, intra-abdominal infections, paediatric infections such as acute epiglottitis and periorbital cellulitis, diabetic foot infections, and skin and soft tissue infections. " 02/01/2004 - "Ampicillin + sulbactam and clindamycin +/- cephalosporin were both well-tolerated and proved equally effective in the treatment of aspiration pneumonia and lung abscess." 10/01/2001 - "Clindamycin, optionally supplemented with a second or third generation cephalosporin and Ampicillin/Sulbactam proved equally effective in treating aspiration pneumonia and primary lung abscess. "
7.	SodiumIBA 01/01/1990 - "In an open, prospective, multicenter trial the clinical efficacy of imipenem/cilastatin sodium (IPM/CS) for the treatment of 14 cases with aspiration pneumonia was investigated. " 10/01/2012 - "To evaluate the efficacy and safety of domestic imipenem cilastatin sodium for the treatments of severe aspiration pneumonia. " 10/01/2012 - "[Domestic imipenem cilastatin sodium for the treatment of severe aspiration pneumonia, a curative effect observation]." 01/01/2006 - "Usefulness of sivelestat sodium administration in patients with aspiration pneumonia." 01/01/1990 - "[Clinical evaluation of therapy for aspiration pneumonia with imipenem/cilastatin sodium]."
8.	meropenem (Merrem)FDA LinkGeneric 01/01/2009 - "Meropenem therapy for aspiration pneumonia is clinically effective and tolerable in elderly patients." 01/01/2009 - "However, the role of anaerobic bacteria in aspiration pneumonia and the clinical efficacy of meropenem in elderly aspiration pneumonia patients have only begun to be investigated. " 01/01/2009 - "Effectiveness of meropenem for the treatment of aspiration pneumonia in elderly patients." 12/30/2003 - "We describe a case of aspiration pneumonia in an immunocompetent patient with multiple sclerosis, caused by a community acquired, multidrug resistant strain of Aeromonas hydrophila sensitive only to meropenem. " 01/01/2015 - "In addition, the patient received meropenem and teicoplanin to treat a urinary tract infection and a bacterial aspiration pneumonia. "
9.	Famotidine (Pepcid)FDA LinkGeneric 11/01/1991 - "We conclude that single-dose oral famotidine and double-dose oral ranitidine are equally effective for preventing acid aspiration syndrome in morbidly obese patients." 04/01/1991 - "[Comparison of the efficacy of famotidine and cimetidine in in prophylaxis of Mendelson's syndrome in elective surgery]." 03/01/1989 - "There was no significant difference between ranitidine and famotidine in respect of the pH. The patients premedicated with famotidine and ranitidine were well protected against Mendelson's syndrome, whereas 38% of patients from the other groups remained at risk." 11/01/1991 - "Famotidine and ranitidine were compared as agents for the prevention of acid aspiration syndrome in 32 morbidly obese patients undergoing vertical banded gastroplasty. "
10.	Butylated Hydroxytoluene (BHT)IBA 07/01/2000 - "BHT can significantly improved the swallowing reflex in PD patients, and therefore can be a hopeful candidate for preventing aspiration pneumonia in PD." 05/01/1999 - "We suggest that BHT improves the impaired swallowing reflex and may help to prevent aspiration pneumonia in the elderly." 12/01/2007 - "To evaluate whether the traditional Chinese herbal medicine banxia houpu tang (BHT, formula magnolia et pinelliae) prevents aspiration pneumonia and pneumonia-related mortality in elderly people. "

Therapies and Procedures

1.	Gastrostomy 09/01/2009 - "The administration of semi-solid nutrients by means of gastrostomy tube has recently been reported to be effective in preventing aspiration pneumonia. " 10/01/2014 - "Feeding via both gastrostomy and nasogastric tube has similar risks for aspiration pneumonia, and continuous pump feeding is not better than intermittent feeding. " 12/01/2013 - "Endoscopic gastrostomy, nasojejunal and oral feeding comparison in aspiration pneumonia patients." 10/01/2013 - "Aspiration pneumonia is an emerging problem in patients receiving gastrostomy feeding. " 05/01/2013 - "Our clinical experience suggested that elemental diets were associated with a reduction in aspiration pneumonia among bedridden patients with percutaneous endoscopic gastrostomy (PEG). "
2.	Enteral Nutrition (Feeding, Tube) 11/01/2005 - "In our study, patients on nasogastric tube feeding did not have a better outcome against aspiration pneumonia and mortality when compared to those who were on oral feeding. " 12/01/2013 - "This is a prospective clinical study of enteral feeding on patients admitted to hospital with aspiration pneumonia. " 01/01/2015 - "Endoscopically guided nasogastric-jejunal feeding tube placement is a simple method and may be useful for patients with aspiration pneumonia due to postgastrectomy. " 01/01/2015 - "Usefulness of endoscopically guided nasogastric-jejunal feeding tube placement in a case of aspiration pneumonia due to postgastrectomy." 10/01/2014 - "Prevention of aspiration pneumonia and increasing survival rates should not be the rationales for tube feeding. "
3.	Oral Hygiene (Dental Hygiene) 12/01/2007 - "Several approaches, including bed positioning, dietary changes, and oral hygiene, have been proposed to prevent aspiration pneumonia, yet few data are available on the efficacy of pharmacologic interventions in reducing the rate of aspiration. " 03/01/2015 - "Oral hygiene reduces the mortality from aspiration pneumonia in frail elders." 01/01/2015 - "However, it is not clear yet which oral hygiene care intervention is most efficacious in reducing the risk of aspiration pneumonia. " 01/01/2015 - "Oral hygiene care reduces the number of oral bacteria and the risk of aspiration pneumonia. " 10/01/2014 - "Oral hygiene can play a positive role in preventing aspiration pneumonia in the elderly. "
4.	Nutritional Support (Artificial Feeding) 06/01/2004 - "It is a safe and effective technique for long-term nutritional support in children, and easy to perform, as only local anesthesia or heavy sedation is required PEG can prevent children from suffering from nasopharyngeal and esophageal erosions due to repeated insertion of nasogastric tubes and the complication of aspiration pneumonia. " 12/01/1987 - "If tube feeding results in the outcome that it is thought to prevent (ie, aspiration pneumonia) then decisions regarding nutritional support in these patients become clinically clearer." 12/01/1995 - "Although jejunostomy has been commonly accepted as superior to gastrostomy for long-term nutritional support because of an assumed lower risk of aspiration pneumonia, recent studies suggest that reevaluation of common practices of surgical tube placement is warranted. " 12/01/2007 - "We found that there is a lack of evidence supporting artificial feeding in the specific outcomes of survival, pressure ulcers, nutrition, and aspiration pneumonia. " 01/01/2014 - "Dysphagia, through alteration of the safety and efficacy of swallowing, is a complication that has an implication for nutritional support, and must be treated to prevent aspiration pneumonia, which is the leading cause of mortality in the stroke patient. "
5.	Home Nursing (Nursing, Home) 01/01/2002 - "The current study sought to determine the key predictors of aspiration pneumonia in a nursing home population with the hope that health care providers could identify those residents at highest risk and focus more efforts on prevention of this serious disease. " 04/01/2007 - "The strongest risk factor for aspiration pneumonia was nursing home residence with a relative risk of 7.1 (p = 0.02) We conclude that the incidence rates and demographics of our ALS population have remained stable over time. " 05/01/2005 - "Aspiration pneumonia is a significant cause of morbidity, hospitalization, and mortality in the nursing home population. " 05/01/2005 - "Can we prevent aspiration pneumonia in the nursing home?" 01/01/2005 - "Prevention of aspiration pneumonia in nursing home patients."