Plastoquinone

Polyunsaturated side-chain quinone derivative which is an important link in the electron transport chain of green plants during the photosynthetic conversion of light energy by photophosphorylation into the potential energy of chemical bonds.

Also Known As:

Networked: 36 relevant articles (2 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Skulachev, Vladimir P: 8 articles (01/2019 - 02/2010)
2.	Zorov, Dmitry B: 4 articles (07/2018 - 01/2012)
3.	Bayrak, Nilüfer: 3 articles (01/2022 - 12/2019)
4.	Yıldırım, Hatice: 3 articles (01/2022 - 12/2019)
5.	Yıldız, Mahmut: 3 articles (01/2022 - 12/2019)
6.	Stelmashook, Elena V: 3 articles (01/2019 - 01/2012)
7.	Pevzner, Irina B: 3 articles (07/2018 - 01/2012)
8.	Plotnikov, Egor Y: 3 articles (07/2018 - 01/2012)
9.	Silachev, Denis N: 3 articles (07/2018 - 01/2012)
10.	Zorova, Ljubava D: 3 articles (07/2018 - 01/2012)

Related Diseases

1.	Colorectal Neoplasms (Colorectal Cancer) 01/21/2022 - "In Vitro and In Silico Study of Analogs of Plant Product Plastoquinone to Be Effective in Colorectal Cancer Treatment."
2.	Infections 01/01/2018 - "Notably, significantly increased efficiency of electron transport from plastoquinone (PQ) to PSI acceptors (REo/ETo) after 20 days of infection suggested greater inhibition on PQ reduction than re-oxidation, and the protection for PSI acceptors might alleviate the reduction of electron transport efficiency beyond PQ upon damaged PSI reaction center. " 01/01/2011 - "The results revealed that damage of oxygen-evolving complex (OEC), decrease of active reaction centers (RCs), and the plastoquinone (PQ) pool as well as significant reduction in the performance indexes (PI) of PSII were caused by the infection of N. "
3.	Breast Neoplasms (Breast Cancer) 06/22/2022 - "Exploring the Anticancer Effects of Brominated Plastoquinone Analogs with Promising Cytotoxic Activity in MCF-7 Breast Cancer Cells via Cell Cycle Arrest and Oxidative Stress Induction." 08/30/2022 - "In Vitro and In Silico Study to Assess Toxic Mechanisms of Hybrid Molecules of Quinone-Benzocaine as Plastoquinone Analogues in Breast Cancer Cells." 11/01/2021 - "Anticancer agents based on Plastoquinone analogs with N-phenylpiperazine: Structure-activity relationship and mechanism of action in breast cancer cells." 01/17/2022 - "Mild anti-oncogenic compounds against breast cancer cell line ZR75 were putatively identified in Malaysian honey that included earlier described antioxidants such as gingerdiol, 2-hexylphenol-O-β-D-xylopyranoside, plastoquinone, tropine isovalerate, plumerinine, and 3,5-(12-phenyl-8-dodecenyl)resorcinol, along with several phenolic esters and lignans."
4.	Stroke (Strokes) 07/27/2018 - "Thus, the mitochondrial-targeted antioxidant derived from plant plastoquinone can effectively protect the brain of newborns both in pre-ischemic and post-stroke conditions, making it a promising candidate for further clinical studies." 01/01/2012 - "We used the cationic plastoquinone derivative, SkQR1, as a mitochondria-targeted antioxidant to alleviate the deleterious consequences of stroke. "
5.	Starvation 12/01/1990 - "(iii) Measurements of the redox state of the plastoquinone pool in state 1 obtained by PS I illumination and in state 2 obtained by various treatments (darkness, anaerobiosis and starvation) show that the plastoquinone pool is oxidized in state 1 and reduced in state 2 except in starved cells where it is still oxidized. " 09/01/2010 - "Nitrogen starvation led to decrease in photochemical quenching and increase in non-photochemical quenching, indicating that cyclic electron transport reduces the plastoquinone pool and acidifies the lumen. " 01/01/2001 - "The data are discussed in terms of a donation of reducing equivalents from mitochondria to chloroplasts and a reduction of the plastoquinone pool via the NAD(P)H-plastoquinone oxidoreductase during CO(2) starvation." 09/01/1980 - "On the other hand, electron donation from endogenous substrates to plastoquinone was suggested from decreases in rate of the cytochrome reduction by dark starvation of cells and also from restoration of fast reduction kinetics by the addition of exogenous substrates to or by reillumination of starved cells.KCN, which completely suppressed respiratory O2-uptake, induced a marked acceleration of the cytochrome reduction in starved cells. "

Related Drugs and Biologics

1.	Oxygen (Dioxygen)
2.	Antioxidants
3.	Benzocaine (Americaine)
4.	quinone (benzoquinone)
5.	Rhodamines
6.	Neuroprotective Agents
7.	Reactive Oxygen Species (Oxygen Radicals)
8.	Chlorophyll
9.	Antineoplastic Agents (Antineoplastics)
10.	Photosystem II Protein Complex (Photosystem II)

Related Therapies and Procedures

1.	Transplantation
2.	Intraperitoneal Injections