A proteolytic enzyme in the serine protease family found in many tissues which converts PLASMINOGEN to FIBRINOLYSIN. It has fibrin-binding activity and is immunologically different from UROKINASE-TYPE PLASMINOGEN ACTIVATOR. The primary sequence, composed of 527 amino acids, is identical in both the naturally occurring and synthetic proteases.
Also Known As:
Alteplase; Activase; T-Plasminogen Activator; Actilyse; Boehringer Ingelheim Brand of Alteplase; Genentech Brand of Alteplase; Hoffmann-La Roche Brand of Alteplase; Lysatec rt-PA; Promeco Brand of Alteplase; TTPA; Tisokinase; Tissue Activator D-44; Alteplase Genentech Brand; Alteplase Promeco Brand; Hoffmann La Roche Brand of Alteplase; Lysatec rt PA; Lysatec rtPA; Plasminogen Activator, Tissue; Plasminogen Activator, Tissue Type; T Plasminogen Activator; Tissue Activator D 44; Tissue Type Plasminogen Activator; Plasminogen Activator, Tissue-Type; Tissue-Type Plasminogen Activator