Phytosterols (Plant Sterols)

01/01/2014 - "Plant sterols decrease sdLDL-C significantly and may be beneficial for children with hypercholesterolemia."
02/01/2014 - "A softgel dietary supplement containing esterified plant sterols and stanols improves the blood lipid profile of adults with primary hypercholesterolemia: a randomized, double-blind, placebo-controlled replication study."
01/01/2014 - "The purpose of this study is to prospectively evaluate the effect of the daily consumption of 2 g of plant sterols on sdLDL-C levels in children with hypercholesterolemia. "
05/01/2010 - "A meta-analysis of randomized controlled trials was performed to summarize direct comparisons between the effect of plant sterols vs plant stanols on serum lipid levels in healthy patients and patients with hypercholesterolemia. "
02/01/2006 - "Therapy and clinical trials: plant sterols and stanols in management of hypercholesterolemia: where are we now?"

12/01/2008 - "Most studies have concentrated on the cytotoxic efficacy of phytosterols on cancer cells. "
01/01/2013 - "In summary, our study provides preclinical proof of the concept that dietary phytosterols could prevent the tumor growth associated with fat-rich diet consumption."
07/01/2010 - "Thus, the aim of our study was to determine whether plant sterols and their thermal processing products (in physiological concentration range) could influence the viability of cancer cells and thus could be considered as positive diet complements. "
07/01/2010 - "Epidemiologic and experimental animal studies indicate that phytosterols are cancer chemopreventive agents particularly against cancers of the colon, breast, and prostate. "
11/01/2005 - "Previous studies from our laboratory on tumor cells suggest that phytosterols stimulate ceramide production, which was associated with cell growth inhibition and stimulation of apoptosis. "

09/01/2011 - "This simulation study showed that the cost-effectiveness of phytosterols/-stanols as monotherapy and as add-on to statins is above thresholds for cost-effectiveness, generally ranging between €20,000 and €50,000, and is thus a non-cost-effective strategy to reduce cardiovascular disease."
09/01/2011 - "The present modelling study aimed to evaluate if and by how much functional foods containing phytosterols/-stanols add to the benefits of statins in the prevention of cardiovascular disease in terms of cost-effectiveness. "
05/01/2008 - "Additional studies investigating relevant clinical endpoints are needed before a diet supplemented with plant sterols can be recommended in the prevention of cardiovascular diseases."
02/01/2014 - "Plant sterols and plant stanols in the management of dyslipidaemia and prevention of cardiovascular disease."
01/01/2014 - "To determine the effectiveness of a rich in phytosterols for reducing markers of cardiovascular disease in young adult population milk. "

01/01/2008 - "These data suggest that plant sterols could have neutral or even protective effects on development of coronary heart disease, which have to be confirmed in interventional trials."
12/01/2008 - "The addition of plant sterols to the diet is suggested by health experts as a safe and effective way to reduce the risk of coronary heart disease."
07/01/2005 - "Estimates of coronary heart disease reduction by 20--25% with plant sterols/stanols is based mainly on short-term studies. "
03/01/2010 - "Phytosterol intake with natural foods, a measure of healthy dietary choices, increases plasma levels, but increased plasma phytosterols are believed to be a coronary heart disease (CHD) risk factor. "
01/01/2010 - "Increased consumption of foods containing plant sterols has the potential to reduce the incidence of coronary heart disease (CHD) and thus reduce costs associated with treating that disease in a significant way. "

02/01/2014 - "Despite possible atherogenicity of marked elevations in circulating levels of plant sterols/stanols, protective effects have been observed in some animal models of atherosclerosis. "
09/01/2009 - "A number of studies have raised the possibility of circulating plant sterols being a risk factor in the pathogenesis of atherosclerosis. "
05/01/2009 - "This study extends existing data regarding the cardioprotective effect of CMG, expands the spectrum of known phytosterols with potent antiatheromatic activity, provides new insight into the mechanisms underlying the beneficial effect of CMG on endothelial function, and may aid in design of new therapy for intervention in atherosclerosis."
12/01/2008 - "The aim of the present study was to determine whether dietary plant sterols and their thermal processing products could influence the viability of normal, abdominal endothelial cells that play a crucial role in atherogenesis. "
12/01/2004 - "The results of this study do not support an association between elevated plasma levels of plant sterols and atherosclerosis."