Phosphorous Acids

Inorganic derivatives of phosphorus trihydroxide (P(OH)3) and its tautomeric form dihydroxyphosphine oxide (HP=O(OH)2). Note that organic derivatives of phosphonic acids are listed under are ORGANOPHOSPHONATES.

Also Known As:

Networked: 20 relevant articles (1 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Berry, Joseph J: 2 articles (05/2015 - 02/2013)
2.	Giordano, Anthony J: 2 articles (05/2015 - 02/2013)
3.	Marder, Seth R: 2 articles (05/2015 - 02/2013)
4.	Mudalige, Anoma: 2 articles (05/2015 - 02/2013)
5.	Pemberton, Jeanne E: 2 articles (05/2015 - 02/2013)
6.	Sang, Lingzi: 2 articles (05/2015 - 02/2013)
7.	Sigdel, Ajaya K: 2 articles (05/2015 - 02/2013)
8.	Pohl, Radek: 2 articles (04/2015 - 02/2010)
9.	Rejman, Dominik: 2 articles (04/2015 - 02/2010)
10.	Batory, Damian: 1 article (11/2020)

Related Diseases

1.	Skeletal Abnormalities Mandibular Hypoplasia Auditory Canal Atresia Short Stature 11/14/2020 - "This study compared the tribological properties in nano- and millinewton load ranges of Ti‑6Al-4V surfaces that were modified using self-assembled monolayers (SAMs) of carboxylic and phosphonic acids. " 06/01/2016 - "Precipitation is also found for phosphonic acids with fluorinated aromatic backbones, while less precipitation occurs upon formation of SAMs with phenylphosphinic anchoring units. " 10/04/2011 - "Surprisingly, the 1-octadecyl phosphonic acids maintain their order as the lateral grain dimensions of the ITO surface shrink to ∼50 nm. It is only when the ITO surface roughness becomes greater than the SAM chain length (∼15 Å) that SAMs are observed to become relatively disordered." 02/19/2013 - "These results not only provide a detailed picture of the molecular structure of a technologically important class of SAMs, but also resolve a long-standing ambiguity regarding the vibrational-mode assignments for phosphonic acids on oxide surfaces, thus improving the utility of PM-IRRAS for future studies." 09/12/2019 - "The assembly concept of the corresponding hierarchical architectures relies on both covalent grafting of phosphonic acids on the NPs surface (SAMs formation; SAM=self-assembled monolayer) and exohedral interdigitation of orthogonal amphiphiles as the second ligand layer driven by solvophobic interactions. "
2.	Retinitis 04/28/2015 - "Systematic structure-activity studies on a diverse family of nucleoside phosphonic acids has led to the development of potent antiviral drugs such as HPMPC (CidofovirTM), PMEA (AdefovirTM), and PMPA (TenofovirTM), which are used in the treatment of CMV-induced retinitis, hepatitis B, and HIV, respectively. "
3.	Hepatitis B 04/28/2015 - "Systematic structure-activity studies on a diverse family of nucleoside phosphonic acids has led to the development of potent antiviral drugs such as HPMPC (CidofovirTM), PMEA (AdefovirTM), and PMPA (TenofovirTM), which are used in the treatment of CMV-induced retinitis, hepatitis B, and HIV, respectively. "
4.	Neoplasms (Cancer) 11/15/2010 - "The concept of sequential cytotoxicity, which states that successive chemical attacks on cellular constituents can be more deleterious to neoplasms than normal cells, was evaluated using a series of 3,5-bis(benzylidene)-1-diethylphosphono-4-oxopiperidines 1 and related phosphonic acids 2, which were screened against a panel of malignant and normal cell lines. " 12/01/2017 - "Dual targeting of cancer-related human matrix metalloproteinases and carbonic anhydrases by chiral N-(biarylsulfonyl)-phosphonic acids."
5.	Human Influenza (Influenza) 01/01/2017 - "The sulfo-sialic acid analogues described in this report are also more potent inhibitors of influenza NA (up to 40-fold) and bacterial NA (up to 8.5-fold) relative to the corresponding anomeric phosphonic acids. " 01/01/2016 - "The phosphonate monoalkyl esters (6b, 6c, 7b, 7c, 8b, and 8c) are better anti-influenza agents (EC50 = 19-89 nM) than their corresponding phosphonic acids (EC50 = 50-343 nM) in protection of cells from the viral infection. "

Related Drugs and Biologics

1.	Oxides
2.	Nucleosides
3.	Antiviral Agents (Antivirals)
4.	Cidofovir (Vistide)
5.	Esters
6.	Organophosphonates (Phosphonates)
7.	Acids
8.	Matrix Metalloproteinases (MMPs)
9.	N-Acetylneuraminic Acid (Sialic Acid)
10.	Glutamic Acid (Glutamate)

Related Therapies and Procedures

1.	Semiconductors