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Phosphofructokinase-1 (Phosphofructokinase 1)

An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. D-tagatose- 6-phosphate and sedoheptulose-7-phosphate also are acceptors. UTP, CTP, and ITP also are donors. In human phosphofructokinase-1, three types of subunits have been identified. They are PHOSPHOFRUCTOKINASE-1, MUSCLE TYPE; PHOSPHOFRUCTOKINASE-1, LIVER TYPE; and PHOSPHOFRUCTOKINASE-1, TYPE C; found in platelets, brain, and other tissues.
Also Known As:
Phosphofructokinase 1; 6 Phosphofructokinase; 6-Phosphofructo-1-kinase; Fructose-6-P 1-Kinase; Fructose-6-phosphate 1-Phosphotransferase; 6-Phosphofructokinase; ATP:D-fructose-6-phosphate 1-phosphotransferase
Networked: 87 relevant articles (1 outcomes, 10 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Sola-Penna, Mauro: 5 articles (06/2013 - 01/2009)
2. Lee, Jong-Ho: 3 articles (11/2021 - 10/2017)
3. Zancan, Patricia: 3 articles (06/2013 - 01/2009)
4. Cho, Eunae Sandra: 2 articles (10/2020 - 01/2017)
5. Kim, Hyun Sil: 2 articles (10/2020 - 01/2017)
6. Kim, Nam Hee: 2 articles (10/2020 - 01/2017)
7. Yook, Jong In: 2 articles (10/2020 - 01/2017)
8. Yun, Jun Seop: 2 articles (10/2020 - 01/2017)
9. Liu, Rui: 2 articles (01/2020 - 10/2017)
10. Lu, Zhimin: 2 articles (01/2020 - 10/2017)

Related Diseases

1. Hyperinsulinism (Hyperinsulinemia)
2. Nasopharyngeal Carcinoma
3. Neoplasms (Cancer)
4. Breast Neoplasms (Breast Cancer)
5. Sepsis (Septicemia)

Related Drugs and Biologics

1. Enzymes
2. Glucose (Dextrose)
3. Citrate (si)-Synthase (Synthase, Citrate)
4. GTP-Binding Proteins (G-Protein)
5. Farnesol
6. Collagen
7. Bile Acids and Salts (Bile Acids)
8. Protein Isoforms (Isoforms)
9. Proteins (Proteins, Gene)
10. Isoenzymes

Related Therapies and Procedures

1. Therapeutics
2. Aftercare (After-Treatment)