Phosphamidon

07/01/1990 - "Phosphamidon was detected by thin-layer chromatography (TLC) from various CNS regions of the rats intoxicated with three doses (1.0, 1.5 and 2.0 mg/kg body-weight) intraperitoneally daily for seven days. "
03/01/1999 - "Treatment of phosphamidon significantly enhanced the mortality and abnormality rates, decreased the average body weights, and cholinesterase activity in chick embryos. "
04/01/1975 - "The administered doses were low, as compared with those of the experiments in vitro: the minimal doses inducing chromosome aberrations in vivo were, in the aldrin treatments 9.56, and in the phosphamidon treatments, 0.07 mug/g body weight. "
12/01/1990 - "Effect of subacute insecticide exposure was studied in male albino mice treated with phosphamidon, propoxur or aldrin at 1/40 LD50 dose intraperitoneally daily for 8 wk. The parameters studies included body weight, pentobarbitone (50 mg/kg) sleeping time, chlorpromazine (6 mg/kg) induced motor incoordination and convulsions induced by leptazol (100 mg/kg) and electrical stimulation (18 mA for 0.2 msec). "

12/01/1990 - "Effect of subacute insecticide exposure was studied in male albino mice treated with phosphamidon, propoxur or aldrin at 1/40 LD50 dose intraperitoneally daily for 8 wk. The parameters studies included body weight, pentobarbitone (50 mg/kg) sleeping time, chlorpromazine (6 mg/kg) induced motor incoordination and convulsions induced by leptazol (100 mg/kg) and electrical stimulation (18 mA for 0.2 msec). "

10/01/2004 - "Phosphamidon was most frequently identified as the cause of poisoning, accounting for 23 mortality events. "
10/01/1970 - "[A case of dimecron poisoning]."
01/01/1975 - "[Protective effect of oxime in phosphamidon poisoning]."
04/01/2004 - "Acute poisoning with phosphamidon: determination of dimethyl phosphate (DMP) as a stable metabolite in a case of organophosphate insecticide intoxication."
01/11/1977 - "The distribution of insecticides in human body tissues in five cases of poisoning by ethyl parathion, malathion, dimethoate, sumithion and phosphamidon has also been studied."

08/01/1987 - "The genotoxic effect of phosphamidon in mice in an in vivo test system was investigated by 3 different assays: chromosomal aberration, micronucleus and sperm-shape abnormality. "
04/01/1975 - "(b) Comparatively, the range of phosphamidon clastogenic doses is very large, scattered between 1.9 and 122 mug/ml. Since, in the phosphamidon treatments, the cellular death begins at a concentration above 244 mug/ml, the chromosome aberrations, induced especially by the low doses, could be maintained in other abnormal cells. "
01/11/1999 - "Fishes exposed to the medium containing 0.05, 0.1 and 0.2 ppm of methyl parathion or 0.5, 1.0, and 2.0 ppm of phosphamidon for a duration of 96 h revealed significant increase in the number of SCE and chromosome aberrations against control values. "
01/11/1999 - "The genotoxic potential of methyl parathion and phosphamidon, two commercial formulations of organophosphorus pesticides, was evaluated through induction of sister chromatid exchanges (SCE) and chromosome aberrations in fish gill tissues. "
04/01/1975 - "The administered doses were low, as compared with those of the experiments in vitro: the minimal doses inducing chromosome aberrations in vivo were, in the aldrin treatments 9.56, and in the phosphamidon treatments, 0.07 mug/g body weight. "

04/01/2013 - "Melatonin attenuates cognitive dysfunction and reduces neural oxidative stress induced by phosphamidon."
10/01/2011 - "Together, the results showed that progesterone attenuated the cognitive dysfunction and increased oxidative stress induced by phosphamidon in the brain."