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Pheochromocytoma

A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)
Also Known As:
Extra-Adrenal Pheochromocytoma; Extra-Adrenal Pheochromocytomas; Pheochromocytoma, Extra Adrenal; Pheochromocytomas; Pheochromocytomas, Extra-Adrenal; Pheochromocytoma, Extra-Adrenal
Networked: 9624 relevant articles (267 outcomes, 964 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Neoplasms (Cancer)
2. Paraganglioma (Paragangliomas)
3. Hypertension (High Blood Pressure)
4. Cushing Syndrome
5. Neuroblastoma

Experts

1. Pacak, Karel: 176 articles (01/2022 - 03/2002)
2. Eisenhofer, Graeme: 100 articles (05/2022 - 03/2002)
3. Gimenez-Roqueplo, Anne-Paule: 42 articles (11/2022 - 10/2004)
4. Lenders, Jacques W M: 38 articles (01/2022 - 03/2002)
5. Timmers, Henri J L M: 32 articles (04/2022 - 03/2007)
6. Tischler, Arthur S: 32 articles (01/2020 - 07/2002)
7. Bornstein, Stefan R: 31 articles (01/2022 - 03/2002)
8. Jimenez, Camilo: 30 articles (01/2022 - 08/2004)
9. Mannelli, Massimo: 29 articles (01/2022 - 03/2002)
10. Takekoshi, Kazuhiro: 29 articles (12/2021 - 03/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Pheochromocytoma:
1. 3-Iodobenzylguanidine (Iobenguane)IBA
2. CatecholaminesIBA
3. Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
4. MetanephrineIBA
5. Norepinephrine (Noradrenaline)FDA LinkGeneric
6. Radioisotopes (Radionuclides)IBA
7. Anesthetics (Anesthetic Agents)IBA
8. NormetanephrineIBA
9. Peptides (Polypeptides)IBA
10. Dopamine (Intropin)FDA LinkGeneric

Therapies and Procedures

1. Adrenalectomy
2. Therapeutics
3. Drug Therapy (Chemotherapy)
4. Anesthesia
5. Length of Stay