Phenethylamines

A group of compounds that are derivatives of beta- aminoethylbenzene which is structurally and pharmacologically related to amphetamine. (From Merck Index, 11th ed)

Also Known As:

Networked: 28 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Sprague, Jon E: 2 articles (01/2020 - 01/2016)
2.	Kronstrand, Robert: 2 articles (01/2018 - 04/2016)
3.	Esteve-Romero, J: 2 articles (05/2001 - 04/2001)
4.	García-Alvarez-Coque, M C: 2 articles (05/2001 - 04/2001)
5.	Gil-Agustí, M: 2 articles (05/2001 - 04/2001)
6.	Monferrer-Pons, L: 2 articles (05/2001 - 04/2001)
7.	Arshaad, Muhammad Imran: 1 article (01/2021)
8.	Broich, Karl: 1 article (01/2021)
9.	Daubner, Johanna: 1 article (01/2021)
10.	Ehninger, Dan: 1 article (01/2021)

Related Diseases

1.	Substance-Related Disorders (Drug Abuse) 01/01/2021 - "Only some members of the substance abuse groups, i.e., phenylethylamines and modafinil, display positive effects on attention and vigilance that are comparable to caffeinated drinks. " 01/01/2015 - "Substituted phenethylamines are a class of designer drugs that have recently emerged in the drug abuse market. " 01/01/2023 - "An important molecular target of structurally related phenethylamines, such as amphetamine, for regulating mood, cognition, movement, and the development of substance use disorder is the dopamine transporter, which limits the range and magnitude of dopamine signaling via reuptake from the extracellular space. " 10/01/2008 - "To avoid drug abuse, 32 substances have been controlled in Japan since April in 2007 by the Pharmaceutical Affairs Law as designated substances (Shitei-Yakubutsu, classified as 11 tryptamines, 11 phenethylamines, 2 piperazines, 6 alkyl nitrites, 1 diterpene and 1 plant). "
2.	Delirium 11/01/2019 - "Delirium was the most frequently reported clinical sign proximal to death and was strongly associated with the phenethylamines." 04/01/2016 - "The toxidromes commonly encountered after ingestion of cathinones and phenylethylamines are mainly of sympathomimetic and hallucinogenic character with a risk of excited delirium and life-threatening cardiovascular effects. " 01/01/2018 - "The toxidromes commonly encountered after ingestion of cathinones and phenethylamines are of sympathomimetic and hallucinogenic character, which includes risk of developing a serotonin syndrome, excited delirium, and life-threatening cardiovascular effects. "
3.	Serotonin Syndrome (Syndrome, Serotonin) 01/01/2018 - "The toxidromes commonly encountered after ingestion of cathinones and phenethylamines are of sympathomimetic and hallucinogenic character, which includes risk of developing a serotonin syndrome, excited delirium, and life-threatening cardiovascular effects. " 05/01/1980 - "A series of substituted phenylethylamines were examined for their relative potencies to 1) release and inhibit accumulation of labeled serotonin in brain synaptosomes, 2) compete with serotonin receptor binding and 3) induce the "serotonin syndrome" in mice. "
4.	Cough 05/30/2001 - "The chromatographic behaviour of some active ingredients in cough-cold pharmaceutical preparations, the antihistamine chlorpheniramine (or the dextro enantiomer dexchlorpheniramine), and the phenethylamines phenylephrine, phenylpropanolamine and pseudoephedrine, has been studied using a C(18) column, micellar mobile phases of sodium dodecyl sulphate (SDS) and pentanol, and with UV detection. " 04/01/2001 - "The chromatographic behaviour of binary and ternary mixtures of several phenethylamines (phenylephrine, phenylpropanolamine, ephedrine, pseudoephedrine and methoxyphenamine) and antihistamines (pheniramine, carbinoxamine, doxylamine, chlorpheniramine, dexchlorpheniramine, dexbrompheniramine, diphenhydramine, tripolidine, azatadine and phenyltoloxamine), found in cough-cold pharmaceutical preparations, was studied using C8, C18 and cyano columns, micellar mobile phases of sodium dodecyl sulfate (SDS) and pentanol and UV detection. "
5.	Drug-Related Side Effects and Adverse Reactions 01/01/2020 - "Phenethylamines (e.g., methamphetamine) are a common source of drug toxicity. "

Related Drugs and Biologics

1.	Sympathomimetics (Sympathomimetic Amines)
2.	Pseudoephedrine
3.	Serotonin (5 Hydroxytryptamine)
4.	Piperazines
5.	Phenylpropanolamine (Dexatrim)
6.	Phenylephrine (Neo-Synephrine)
7.	Methamphetamine (Desoxyn)
8.	Histamine Antagonists (Antihistamines)
9.	Dopamine (Intropin)
10.	Chlorpheniramine (Chlorphenamine)