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Phenelzine (Nardil)

One of the MONOAMINE OXIDASE INHIBITORS used to treat DEPRESSION; PHOBIC DISORDERS; and PANIC.

Also Known As:

Nardil; 2-Phenethylhydrazine; Nardelzine; Parke Davis Brand of Phenelzine Sulfate; Pfizer Brand of Phenelzine Sulfate; Phenelzine Sulfate; Phenethylhydrazine; United Drug Brand of Phenelzine Sulfate; Warner Chilcott Brand of Phenelzine Sulfate; beta-Phenylethylhydrazine; 2 Phenethylhydrazine; Sulfate, Phenelzine; beta Phenylethylhydrazine; Fenelzin; Hydrazine, (2-phenylethyl)-

Networked: 245 relevant articles (30 outcomes, 36 trials/studies)

Relationship Network

Drug Context: Research Results

Organic Chemicals: 58
- Hydrazines: 39
  - Phenelzine: 245

Experts

1.	Baker, Glen B: 5 articles (08/2014 - 01/2002)
2.	Ullah, Nasir: 2 articles (08/2014 - 06/2013)
3.	Nunes, Emerson: 2 articles (08/2014 - 06/2013)
4.	Matveychuk, Dmitriy: 2 articles (08/2014 - 06/2013)
5.	Tenorio, Gustavo: 2 articles (09/2013 - 11/2011)
6.	Wong, Grace: 2 articles (09/2013 - 11/2011)
7.	Kerr, Bradley J: 2 articles (09/2013 - 11/2011)
8.	Bisson, Jonathan I: 2 articles (01/2010 - 01/2007)
9.	Baker, G B: 2 articles (07/2001 - 05/2000)
10.	Muñoz-Aguilera, Eva María: 1 article (06/2015)

Related Diseases

1.	Phobic Disorders (Phobia) 11/01/1992 - "Four (80%) of 5 patients with comorbid generalized social phobia receiving phenelzine had marked improvement of OCD symptoms. " 01/01/2003 - "Phenelzine is effective in social phobia, and no treatment has been shown to be superior to phenelzine. " 01/01/2003 - "Phenelzine appears to be effective in treating social phobia that has been unresponsive to other treatments. " 10/01/1999 - "Cognitive behavioral group therapy and phenelzine both effective in social phobia." 01/01/1990 - "Phenelzine appeared to be a particularly effective treatment for the generalized form of social phobia. "
2.	Panic Disorder (Panic Attack) 02/01/2007 - "Successful use of phenelzine in treatment-resistant panic disorder." 01/01/1989 - "Phenelzine has been used most often with good effect and is regarded by some as the treatment of first choice for panic disorders. " 11/01/1988 - "Tolerance to the therapeutic effects of phenelzine developed in three patients with panic disorder. " 11/01/1988 - "Tolerance to the therapeutic effect of phenelzine in patients with panic disorder." 08/01/1988 - "Results suggest that phenelzine may be a preferred drug for treating depressed patients with panic attacks."
3.	Post-Traumatic Stress Disorders (PTSD) 05/01/1988 - "The findings are discussed in the light of preliminary reports suggesting that phenelzine may be an effective treatment for posttraumatic stress disorder." 05/01/1988 - "Thirteen patients meeting DSM-III criteria for posttraumatic stress disorder participated in a random-assignment, double-blind crossover trial comparing phenelzine (45-75 mg/day) and placebo. " 05/01/1988 - "A controlled trial of phenelzine in posttraumatic stress disorder." 11/01/1987 - "Twenty-five Israeli combat veterans fulfilling DSM-III criteria for posttraumatic stress disorder (PTSD) participated in an open, prospective trial of phenelzine sulfate administration (median daily dose, 60 mg; range, 30 to 90 mg); three patients withdrew early due to side effects. " 07/31/1996 - "Moreover, no beneficial effect of phenelzine was detected in the patients (as assessed by PTSD, anxiety, and depression scales)."
4.	Bulimia (Binge Eating) 01/01/1987 - "A controlled trial of phenelzine in bulimia." 01/01/1985 - "Thirty normal weight women with bulimia completed a double-blind, placebo-controlled trial of phenelzine sulfate. " 01/01/1985 - "A double-blind trial of phenelzine in bulimia." 06/01/1991 - "While medical problems related to the bulimia were few, treatment with phenelzine was associated with three reports of serious hypertensive episodes, one of which led to death. " 05/01/1988 - "Phenelzine vs placebo in 50 patients with bulimia."
5.	Migraine Disorders (Migraine) 11/01/1995 - "Phenelzine was associated with a large decrease in the frequency and severity of migraine attacks. " 11/01/1995 - "The goals of the study are (1) to investigate the safety of concomitant treatment of migraine with beta-blockers and phenelzine, (2) to assess whether orthostatic hypertension and other side effects would be relieved, and (3) to compare the results of this open trial of phenelzine to those of a previous study using similar methods. " 12/01/1997 - "Although effective for prevention of migraine, methysergide and phenelzine are usually relegated to last-resort use because of potentially serious side effects. " 11/01/1995 - "This paper presents the results of a study comparing the effectiveness of a beta-adrenergic blocking agent, atenolol, a monoamine oxidase inhibitor (MAO-I), phenelzine, and the combination in treatment of 61 adults with migraine headache. "

Related Drugs and Biologics

1.	Imipramine (Janimine)
2.	Monoamine Oxidase Inhibitors (Monoamine Oxidase Inhibitor)
3.	Alprazolam (Xanax)
4.	Tricyclic Antidepressive Agents (Tricyclic Antidepressants)
5.	Benzodiazepines
6.	Serotonin Uptake Inhibitors (Serotonin Reuptake Inhibitors)
7.	Fluoxetine (Prozac)
8.	Amitriptyline (Elavil)
9.	Desipramine (Pertofrane)
10.	Haloperidol (Haldol)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Psychodrama
3.	Intraperitoneal Injections
4.	Oral Administration