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Peripheral Nervous System Neoplasms

Neoplasms which arise from peripheral nerve tissue. This includes NEUROFIBROMAS; SCHWANNOMAS; GRANULAR CELL TUMORS; and malignant peripheral NERVE SHEATH NEOPLASMS. (From DeVita Jr et al., Cancer: Principles and Practice of Oncology, 5th ed, pp1750-1)
Also Known As:
Peripheral Nerve Neoplasms; Peripheral Nerve Neoplasms, Benign; Peripheral Nerve Neoplasms, Malignant; Peripheral Nerve Neoplastic Infiltration; Peripheral Nerve Tumors; Peripheral Nervous System Benign Neoplasms; Peripheral Nervous System Malignant Neoplasms; Neoplasm, Peripheral Nerve; Neoplasms, Peripheral Nerve; Nerve Neoplasm, Peripheral; Nerve Neoplasms, Peripheral; Nerve Tumor, Peripheral; Nerve Tumors, Peripheral; Peripheral Nerve Neoplasm; Peripheral Nerve Tumor; Tumor, Peripheral Nerve; Tumors, Peripheral Nerve
Networked: 48 relevant articles (1 outcomes, 4 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Wounds and Injuries (Trauma)
2. Prostatic Neoplasms (Prostate Cancer)
3. Peripheral Nervous System Diseases (PNS Diseases)
4. Lung Neoplasms (Lung Cancer)
5. Leprosy (Hansen's Disease)

Experts

1. Ratner, Nancy: 2 articles (01/2013 - 05/2006)
2. Wu, Jianqiang: 2 articles (01/2013 - 05/2006)
3. Gutmann, David H: 2 articles (12/2005 - 02/2004)
4. Perry, Arie: 2 articles (12/2005 - 02/2004)
5. Bryant, Jean-Paul: 1 article (01/2022)
6. Govindarajan, Vaidya: 1 article (01/2022)
7. Levi, Allan D: 1 article (01/2022)
8. Lu, Victor M: 1 article (01/2022)
9. Perez-Roman, Roberto J: 1 article (01/2022)
10. Chang, Tommy Nai-Jen: 1 article (07/2021)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Peripheral Nervous System Neoplasms:
1. Phosphopyruvate Hydratase (Enolase)IBA
2. Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
3. NAD (NADH)IBA
4. S100 Proteins (S 100 Protein)IBA
5. Ethylnitrosourea (N-Ethyl-N-nitrosourea)IBA
01/01/1990 - "Immunohistochemical characterization of rat central and peripheral nerve tumors induced by ethylnitrosourea."
01/01/1973 - "Biological characteristics of peripheral nerve tumors induced with ethylnitrosourea."
10/01/1999 - "Peripheral nerve tumors (PNT) and melanomas induced transplacentally on day 14 of gestation in Syrian golden hamsters by N-nitrosoethylurea were analyzed for activated oncogenes by the NIH 3T3 transfection assay, and for mutations in the neu oncogene by direct sequencing, allele-specific oligonucleotide hybridization, MnlI restriction-fragment-length polymorphism, single-strand conformation polymorphism, and mismatch amplification mutation assays. "
01/01/1989 - "The majority of spontaneous peripheral nerve tumors were of cystic histological structure identical to that of cystic neurinomas induced in rats by ethylnitrosourea and almost all of these tumors were S-100 protein positive. "
01/01/1990 - "Ethylnitrosourea-induced central and peripheral nerve tumors in Sprague-Dawley rats were tested for GFAP (Glial Fibrillary Acidic Protein), S-100 protein, NSE (Neuron Specific Enolase) and Anti-Leu 7 (HNK-1) immunoreactivity utilizing the ABC method (avidin-biotin-complex) for GFAP, S-100 protein and NSE, and the PAP method (peroxidase-antiperoxidase) for Anti-Leu 7. Peripheral nerve neurinomas were consistently positive for S-100 protein and consistently negative for GFAP and Anti-Leu 7. Neurinomas would occasionally exhibit positive staining for NSE (2 of 55 tumors). "
6. Fluorescein (Funduscein)FDA LinkGeneric
7. Proteins (Proteins, Gene)FDA Link
8. Neurofibromin 1 (Neurofibromin)IBA
9. Monophenol Monooxygenase (Tyrosinase)IBA
10. Formaldehyde (Formol)FDA Link

Therapies and Procedures

1. Therapeutics
2. Decompression
3. Radiotherapy
4. Surgical Amputation (Amputations)
5. Thoracoscopes