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Pepsin A (Pepsin)

Formed from pig pepsinogen by cleavage of one peptide bond. The enzyme is a single polypeptide chain and is inhibited by methyl 2-diaazoacetamidohexanoate. It cleaves peptides preferentially at the carbonyl linkages of phenylalanine or leucine and acts as the principal digestive enzyme of gastric juice.
Also Known As:
Pepsin; Pepsin 1; Pepsin 3
Networked: 1488 relevant articles (54 outcomes, 193 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Johnston, Nikki: 31 articles (06/2022 - 12/2004)
2. Samuels, Tina L: 17 articles (06/2022 - 11/2009)
3. Dettmar, Peter W: 16 articles (01/2022 - 02/2002)
4. He, Zhaoping: 8 articles (11/2020 - 07/2007)
5. Sifrim, Daniel: 7 articles (01/2019 - 04/2008)
6. Blumin, Joel H: 6 articles (06/2022 - 12/2007)
7. Saussez, Sven: 6 articles (09/2021 - 01/2019)
8. Magliulo, Giuseppe: 5 articles (07/2022 - 02/2013)
9. Lechien, Jerome R: 5 articles (09/2021 - 01/2019)
10. Li, Xiang-Ping: 5 articles (03/2021 - 02/2009)

Related Diseases

1. Gastroesophageal Reflux (GERD)
2. Ulcer
3. Duodenal Ulcer (Curling's Ulcer)
4. Laryngopharyngeal Reflux
5. Stomach Ulcer (Gastric Ulcer)

Related Drugs and Biologics

1. Acids
2. Peptide Hydrolases (Proteases)
3. Proteins (Proteins, Gene)
4. Proton Pump Inhibitors
5. Antigen-Antibody Complex (Immune Complex)
6. Gastrins
7. Trypsin
8. Dinoprostone (PGE2)
9. Omeprazole (Prilosec)
10. gamma-Globulins (gamma-Globulin)

Related Therapies and Procedures

1. Vagotomy
2. Therapeutics
3. Proximal Gastric Vagotomy
4. Lung Transplantation
5. Electronic Nose