Pentoxyl

5-Hydroxymethyl-6-methyl- 2,4-(1H,3H)-pyrimidinedione. Uracil derivative used in combination with toxic antibiotics to lessen their toxicity; also to stimulate leukopoiesis and immunity. Synonyms: pentoksil; hydroxymethylmethyluracil.

Also Known As:

Networked: 47 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Dysentery 05/01/1966 - "[Treatment of dysentery in children with Pentoxyl in combination with antibacterial preparations]." 02/01/1961 - "[Clinico-immunological indices during biomycin, pentoxyl and vaccine therapy of patients with acute dysentery]." 01/01/1976 - "[Study of preventive properties of blood serum in patients with dysentery treated with oletetrin combined with methyluracil or pentoxyl]." 01/01/1968 - "[Dynamics of phagocytic activity of leukocytes and protein fractions in dysentery patients treated with antibiotics and by a combined method (antibiotics, pentoxyl and bacteriophages)]." 12/01/1964 - "[COMPARATIVE CLINICAL-IMMUNOLOGICAL EVALUATION OF RESULTS OF TREATING ACUTE DYSENTERY WITH TETRACYCLINE AND A COMBINED METHOD (TETRACYCLINE, VACCINE AND PENTOXYL)]."
2.	Wounds and Injuries (Trauma) 02/01/1978 - "Clinico-experimental study of the pentoxyl and methyluracil effect upon the natural resistance in mitral stenosis cases is presented together with the findings obtained in the experiments dealing with the healing of the wounds infected with pathogenic staphylococcus. " 02/01/1978 - "The inflammation of the wound was less pronounced in the animals treated with pentoxyl and methyluracil. "
3.	Mitral Valve Stenosis (Mitral Stenosis) 02/01/1978 - "Clinico-experimental study of the pentoxyl and methyluracil effect upon the natural resistance in mitral stenosis cases is presented together with the findings obtained in the experiments dealing with the healing of the wounds infected with pathogenic staphylococcus. "
4.	Hypersensitivity (Allergy) 01/01/1984 - "It is recommended that patients with chronic bronchitis exacerbation should receive pentoxyl (during immunoglobulin deficiency and proneness to allergy), becotide inhalations to obtain primarily desensitization effect, and combined pentoxyl and becotide (in patients with high risk of sensitization)." 01/01/1984 - "The authors provide comparative data derived during study of the time-course of changes in IgM, IgG and IgA and cellular eosinophilic and basophilic allergic reactions during application of pentoxyl and becotide alone and combined in multiple modality treatment of 161 patients with chronic obstructive bronchitis. "
5.	Bronchitis 01/01/1984 - "The authors provide comparative data derived during study of the time-course of changes in IgM, IgG and IgA and cellular eosinophilic and basophilic allergic reactions during application of pentoxyl and becotide alone and combined in multiple modality treatment of 161 patients with chronic obstructive bronchitis. "

Related Drugs and Biologics

1.	6-methyluracil
2.	Immunoglobulin M (IgM)
3.	Immunoglobulin G (IgG)
4.	Immunoglobulin A (IgA)
5.	Beclomethasone (Beclometasone)
6.	oletetrin
7.	Chloramphenicol (Chloromycetin)
8.	Anti-Bacterial Agents (Antibiotics)
9.	Gentamicins (Gentamicin)
10.	Antigens

Related Therapies and Procedures

1.	Therapeutics