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Pentoxifylline (Trental)

A METHYLXANTHINE derivative that inhibits phosphodiesterase and affects blood rheology. It improves blood flow by increasing erythrocyte and leukocyte flexibility. It also inhibits platelet aggregation. Pentoxifylline modulates immunologic activity by stimulating cytokine production.
Also Known As:
Trental; Oxpentifylline; Pentoxil; Agapurin; BL-191; Torental; BL 191; BL191; 1H-Purine-2,6-dione, 3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl)-
Networked: 2585 relevant articles (380 outcomes, 651 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Coimbra, Raul: 18 articles (06/2010 - 11/2003)
2. Tsai, Tun-Jun: 12 articles (11/2017 - 12/2002)
3. Gude, Rajiv P: 12 articles (03/2014 - 08/2003)
4. Chen, Yung-Ming: 11 articles (12/2021 - 12/2002)
5. Chiang, Wen-Chih: 11 articles (12/2021 - 12/2002)
6. Bravo-Cuellar, Alejandro: 11 articles (03/2021 - 03/2006)
7. Belcaro, G: 11 articles (01/2002 - 01/2002)
8. Cesarone, M R: 11 articles (01/2002 - 01/2002)
9. De Sanctis, M T: 11 articles (01/2002 - 01/2002)
10. Geroulakos, G: 11 articles (01/2002 - 01/2002)

Related Diseases

1. Intermittent Claudication
2. Alcoholic Hepatitis
3. Fibrosis (Cirrhosis)
4. Neoplasms (Cancer)
5. Sepsis (Septicemia)

Related Drugs and Biologics

1. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
2. Adrenal Cortex Hormones (Corticosteroids)
3. Pentoxifylline (Trental)
4. Cytokines
5. Vitamin E
6. Tocopherols (Tocopherol)
7. Prednisolone (Predate)
8. Antioxidants
9. Cilostazol (Pletal)
10. Steroids

Related Therapies and Procedures

1. Therapeutics
2. Oral Administration
3. Conservative Treatment
4. Resuscitation
5. Drug Therapy (Chemotherapy)