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Penile Induration (Peyronie's Disease)

A condition characterized by hardening of the PENIS due to the formation of fibrous plaques on the dorsolateral aspect of the PENIS, usually involving the membrane (tunica albuginea) surrounding the erectile tissue (corpus cavernosum penis). This may eventually cause a painful deformity of the shaft or constriction of the urethra, or both.
Also Known As:
Peyronie's Disease; Peyronie Disease; Penile Fibromatosis; Plastic Induration of the Penis; Cavernitides, Fibrous; Fibromatosis, Penile; Fibrous Cavernitides; Fibrous Cavernitis; Peyronies Disease; Cavernitis, Fibrous
Networked: 1139 relevant articles (115 outcomes, 169 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Pain (Aches)
2. Erectile Dysfunction
3. Congenital Abnormalities (Deformity)
4. Fibrosis (Cirrhosis)
5. Priapism

Experts

1. Levine, Laurence A: 39 articles (06/2021 - 03/2002)
2. Hellstrom, Wayne J G: 38 articles (01/2021 - 07/2003)
3. Yafi, Faysal A: 31 articles (09/2022 - 01/2015)
4. Trost, Landon: 21 articles (01/2022 - 12/2015)
5. Hatzichristodoulou, Georgios: 19 articles (09/2022 - 11/2013)
6. Falcone, Marco: 17 articles (05/2021 - 09/2012)
7. Garaffa, Giulio: 16 articles (05/2022 - 11/2006)
8. Ziegelmann, Matthew J: 15 articles (01/2022 - 04/2016)
9. Seftel, Allen D: 15 articles (10/2020 - 08/2012)
10. Ralph, David J: 14 articles (03/2021 - 07/2006)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Penile Induration:
1. Microbial Collagenase (Clostridiopeptidase A)FDA Link
2. Verapamil (Calan)FDA LinkGeneric
3. InterferonsIBA
4. Dexamethasone (Maxidex)FDA LinkGeneric
5. Vitamin EFDA LinkGeneric
6. Collagenases (Collagenase)FDA Link
7. ColchicineFDA LinkGeneric
8. Phosphodiesterase 5 InhibitorsIBA
9. Interferon-alpha (Interferon Alfa)IBA
10. Pentoxifylline (Trental)FDA LinkGeneric

Therapies and Procedures

1. Therapeutics
2. Extracorporeal Shockwave Therapy
3. Penile Prosthesis (Penile Implants)
4. Intralesional Injections
5. Conservative Treatment