HOME PRODUCTS SERVICES COMPANY CONTACT FAQ

Penicillinase

Subscribe to New Research on Penicillinase

A beta-lactamase preferentially cleaving penicillins. (Dorland, 28th ed) EC 3.5.2.-.

Also Known As:

AER-I beta-Lactamase; Benzylpenicillinase; Carbenicillinase; Exopenicillinase; beta Lactamase III; beta Lactamase RP4; gamma-Penicillinase; AER I beta Lactamase; Lactamase III, beta; Lactamase RP4, beta; beta Lactamase I; beta-Lactamase, AER-I; gamma Penicillinase; beta-Lactamase I

Networked: 339 relevant articles (19 outcomes, 18 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Enzymes and Coenzymes
- Enzymes: 34502
  - Hydrolases: 639
    - Amidohydrolases: 12
      - beta-Lactamases: 2061
        Penicillinase: 339
        prepenicillinase

Experts

1.	Moreillon, Philippe: 2 articles (10/2005 - 11/2004)
2.	Entenza, José M: 2 articles (10/2005 - 11/2004)
3.	Harinath, B C: 2 articles (04/2003 - 06/2001)
4.	He, Tao: 1 article (09/2015)
5.	Wu, Congming: 1 article (09/2015)
6.	Wang, Yang: 1 article (09/2015)
7.	Qian, Minyi: 1 article (09/2015)
8.	Xiao, Xilong: 1 article (09/2015)
9.	Tang, Shusheng: 1 article (09/2015)
10.	Chen, Tingting: 1 article (09/2015)

Related Diseases

1.	Infection 08/01/1986 - "Successful therapy of penicillinase-producing Neisseria gonorrhoeae pharyngeal infection during pregnancy." 11/01/1986 - "It is effective against infections by penicillinase-producing Neisseria gonorrhoeae. " 11/01/2009 - "We surveyed the rate of chlamydial and gonococcal infections among human immunodeficiency virus (HIV)-seropositive patients in Thailand as well as the current status of antimicrobial resistance of Neisseria gonorrhoeae and determined the prevalence of penicillinase-producing N. " 09/01/1999 - "Infections with penicillinase producing N. " 01/01/1999 - " Infections caused by penicillinase-producing gonococci were strongly associated with contacts outside the country or with foreigners and their incidence was characterized by erratic time fluctuations, suggesting that they have not become endemic in the Greek population. "
2.	Urethritis 01/01/1988 - "[Detection of penicillinase-producing Neisseria gonorrhoeae from male patients with urethritis]." 09/21/1985 - "Among 208 men with culture-proven gonococcal urethritis, the fluorescent spot test was positive in 92 of 101 men from whom penicillinase-producing N gonorrhoeae (PPNG) were isolated and in 4 of 107 men from whom non-PPNG were isolated. " 07/19/1984 - "Ninety-two men with culture-proved gonococcal urethritis, 46 per cent with penicillinase-producing N. " 02/01/1982 - "Penicillinase-producing strains of Neisseria gonorrhoeae (PPNG) were detected in nine out of 27 (3.2%) treatment failures in 310 cases of acute gonococcal urethritis in men in Lusaka, Zambia. " 11/01/1986 - "Between January and April 1984, 229 of 448 male patients with urethritis at the Choong-Ku Venereal Disease Clinic in Seoul had positive urethral cultures: 66 for penicillinase-producing Neisseria gonorrhoeae (PPNG) and 163 for non-penicillinase-producing N. "
3.	Endocarditis 11/01/2004 - "LB11058 was tested in vitro and in rats with experimental aortic endocarditis against three methicillin-resistant Staphylococcus aureus (MRSA) strains, one penicillinase-negative strain (strain COL), and two penicillinase-producing strains (COL-Bla+ and P8-Hom). " 09/01/1992 - "To our knowledge this is the first reported case of gonococcal endocarditis secondary to infection with a penicillinase-producing organism." 09/01/1992 - "We report the case of a patient with fulminant endocarditis secondary to infection with penicillinase-producing Neisseria gonorrhoeae (PPNG). " 09/01/1992 - "Fulminant endocarditis due to infection with penicillinase-producing Neisseria gonorrhoeae." 01/01/1979 - "Thus, the semisynthetic, penicillinase-resistant penicillins are unlikely to be effective in the therapy of patients with enterococcal endocarditis."
4.	Chancroid 11/01/1984 - "Amoxicillin-clavulanic acid has also successfully cured urethritis in men caused by penicillinase-producing Neisseria gonorrhoeae and is superior to amoxicillin alone for beta-lactamase-positive Haemophilus ducreyi infections (chancroid). "
5.	Gonorrhea 02/01/2000 - "This study determined the prevalence of antimicrobial resistance by Neisseria gonorrhoeae, including penicillinase-producing gonorrhea (PPNG) strains, and monitored the trends. " 03/01/2000 - "Despite declining rates of gonorrhea, the relative rate of penicillinase-producing strains is increasing, especially in South-East Asia. " 11/01/1997 - "The results were compared with data obtained in three Finnish laboratories in 1986 and contrasted with the development of the incidence of gonorrhea and the prevalence of penicillinase-producing N. " 07/01/1994 - "The appearance and the endemic of penicillinase-producing Neisseria gonorrhoeae (PPNG) and other resistant strains cause much difficulty in the treatment of gonorrhea. " 06/01/1991 - "Fifty percent of Neisseria Gonorrhea cultured were penicillinase producers. "

Related Drugs and Biologics

1.	Penicillins (Penicillin)
2.	beta-Lactamases (beta-Lactamase)
3.	Cefoxitin (Cefoxitin Sodium)
4.	Probenecid (Benemid)
5.	Amoxicillin-Potassium Clavulanate Combination (Co-amoxiclav)
6.	Thiamphenicol
7.	Spectinomycin (Spectinomycin Hydrochloride)
8.	Methicillin (Metin)
9.	Ciprofloxacin (Cipro)
10.	Cefuroxime (Zinacef)

Related Therapies and Procedures

1.	Chemoprevention
2.	Transplants (Transplant)
3.	Catheters
4.	Hip Replacement Arthroplasty (Total Hip Replacement)
5.	Stents