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Penicillin V (Phenoxymethylpenicillin)

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A broad-spectrum penicillin antibiotic used orally in the treatment of mild to moderate infections by susceptible gram-positive organisms.

Also Known As:

Phenoxymethylpenicillin; Betapen; Apocillin; Beromycin; Beromycin, Penicillin; Berromycin, Penicillin; Fenoxymethylpenicillin; Pen VK; Penicillin V Potassium; Penicillin V Sodium; Penicillin VK; V-Cillin K; Vegacillin; Penicillin Beromycin; Penicillin Berromycin; Phenoxymethyl Penicillin; Potassium, Penicillin V; Sodium, Penicillin V; V Cillin K; V Sodium, Penicillin; VCillin K; Penicillin, Phenoxymethyl; 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-((phenoxyacetyl)amino)-, (2S-(2alpha,5alpha,6beta))-

Networked: 431 relevant articles (66 outcomes, 97 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1.	Mölstad, Sigvard: 5 articles (01/2010 - 01/2002)
2.	Blanca, M: 2 articles (08/2015 - 01/2009)
3.	Reveiz, Ludovic: 2 articles (01/2015 - 01/2013)
4.	Cardona, Andrés Felipe: 2 articles (01/2015 - 01/2013)
5.	O'Sullivan, Ronan: 2 articles (06/2014 - 01/2013)
6.	Wakai, Abel: 2 articles (06/2014 - 01/2013)
7.	Quirke, Michael: 2 articles (06/2014 - 01/2013)
8.	Miravitlles, Marc: 2 articles (01/2013 - 12/2005)
9.	Brudin, Lars: 2 articles (01/2010 - 09/2007)
10.	Neumark, Thomas: 2 articles (01/2010 - 09/2007)

Related Diseases

1.	Pharyngitis (Sore Throat) 02/01/2004 - "Penicillin V for 10 days is the standard therapy and is effective in the management of GABHS pharyngitis. " 02/01/1989 - "To determine if a single daily dose of penicillin V would be effective in the treatment of group A beta-hemolytic streptococcal (GABHS) pharyngitis, 154 patients with GABHS pharyngitis were randomly assigned to receive 750 mg of penicillin V once daily for ten days or 250 mg of penicillin V three times daily for ten days. " 11/01/1985 - "The results of this and earlier investigations suggest that penicillin V given twice daily is as effective as penicillin V given three times daily for the treatment of GABHS pharyngitis." 10/01/1996 - "A randomized double-blind placebo-controlled clinical trial was undertaken in patients aged 4-60 years to assess the efficacy of penicillin V on the clinical course and bacteriological response in patients with sore throat in general practice. " 11/01/2001 - "Two randomized, single-blind, multicenter antibiotic efficacy trials in children using recommended doses of either oral penicillin V or intramuscular BPG for treatment of acute-onset pharyngitis associated with isolation of group A streptococci were conducted. "
2.	Tonsillitis 01/01/1991 - "In conclusion, phenoxymethylpenicillin dosed 2 or 3 times daily seems to be equally effective in tonsillitis due to group A streptococci." 01/01/1991 - "In relation to compliance problems it was investigated whether phenoxymethylpenicillin dosed twice or 3 times daily was equally effective in tonsillitis due to beta-haemolytic streptococci group A. " 06/01/1995 - "In streptococcal acute tonsillitis clinical studies, with a 1.5 g dose regimen over 5 days, clinical results and bacterial eradication are identical to those obtained in the Penicillin V groups. " 01/01/1991 - "Phenoxymethylpenicillin two or three times daily for tonsillitis with beta-haemolytic streptococci group A: a blinded, randomized and controlled clinical study." 08/30/1958 - "Treatment of tonsillitis; a therapeutic trial of phenoxymethyl penicillin in a food-borne epidemic of tonsillitis."
3.	Infection 01/01/1991 - "In conclusion phenoxymethylpenicillin dosed 2 or 3 times daily seems to be equally effective in bacterial upper respiratory infection." 05/01/1985 - "In this study the antimicrobial effects of phenoxymethylpenicillin (PM) and pheneticillin (PE) in vitro and in an experimental animal infection model were compared as well as the pharmacokinetic properties of both drugs in patients. " 11/01/1956 - "[Studies on prophylactic action of phenoxymethyl penicillin in experimental anaerobic infections]." 01/01/2013 - "In some Scandinavian countries, this infection is treated with penicillin V since the resistances of pneumococci to this antibiotic are low. " 03/01/2012 - "To investigate whether the increase in the number of doses of penicillin V from three times daily to four times daily for common infections, as recommended in the new Norwegian guidelines for antibiotic treatment in primary health care, would lead to reduced patient compliance. "
4.	Endocarditis 07/07/1997 - "He was treated successfully with penicillin V. The ER bacteraemia occurred without complications of endocarditis." 10/01/1987 - "Efficacy of orally administered penicillin V for prophylaxis of experimentally induced streptococcal endocarditis." 02/01/1987 - "In the light of these findings and the reports of other workers it is suggested that penicillin V may no longer be the most appropriate drug for endocarditis prophylaxis, despite the most recent recommendations of the American Heart Association. " 01/01/1982 - "High dose phenoxymethylpenicillin for preventing endocarditis." 10/01/1987 - "A single-oral-dose penicillin V regimen (36 mg/kg of body weight) prevented endocarditis when rabbits were challenged with 10(4) CFU, but protection diminished with increasing inoculum concentrations. "
5.	Maxillary Sinusitis 10/02/2000 - "The aim of the study was to compare the effectiveness of penicillin V with placebo in the treatment of adult patients with acute maxillary sinusitis (in general practice). " 03/01/2000 - "Randomised, double blind, placebo controlled trial of penicillin V in the treatment of acute maxillary sinusitis in adults in general practice." 03/01/2000 - "To compare the effectiveness of penicillin V with placebo in the treatment of adult patients with acute maxillary sinusitis in general practice. " 10/02/2000 - "Penicillin V is more effective than placebo in the treatment of acute maxillary sinusitis in adults in general practice, but only in patients with pronounced pain." 03/01/2000 - "Penicillin V is more effective than placebo in the treatment of acute maxillary sinusitis in adults in general practice, but only in patients with pronounced pain."

Related Drugs and Biologics

1.	Amoxicillin (Wymox)
2.	Penicillin V (Phenoxymethylpenicillin)
3.	Clarithromycin (Biaxin)
4.	cefuroxime axetil (Ceftin)
5.	Penicillins (Penicillin)
6.	Clavulanic Acid (Potassium Clavulanate)
7.	Azithromycin (Zithromax)
8.	Amoxicillin-Potassium Clavulanate Combination (Co-amoxiclav)
9.	cefpodoxime proxetil (Vantin)
10.	cefdinir (CFDN)

Related Therapies and Procedures

1.	Tonsillectomy
2.	Pulpectomy
3.	Aftercare (After-Treatment)
4.	Antibiotic Prophylaxis
5.	Splenectomy