Penbutolol

09/30/1987 - "Penbutolol has proved particularly effective and suitable for the treatment, even on a long-term basis, of recently developed hypertension, especially in its hyperkinetic forms. "
12/01/2016 - "Penbutolol sulfate is a potent, noncardioselective beta-blocker, which is used for the management of hypertension. "
11/01/1996 - "Betapressin is recommended for monotherapy of patients suffering from stages I-II hypertension with eu- and hypokinetic types of hemodynamics."
11/01/1996 - "[The pharmacological effect of betapressin in hypertension]."
06/01/1990 - "[Validity of the use of penbutolol in essential arterial hypertension]."

02/01/1984 - "Efficacy of once daily penbutolol in chronic stable angina. "
01/01/1993 - "Ventricular arrhythmias during exercise testing and daily activities in patients with stable angina pectoris before and during Aldisem and penbutolol treatment."
04/05/1986 - "[Long-term treatment of stable angina pectoris with penbutolol]."
01/01/1984 - "In order to test the additional efficacy of the combination of a beta blocker (penbutolol 40 mg single dose) with molsidomine (2 mg single dose), a double blind cross-over trial was performed in 30 patients with stable angina pectoris. "
02/01/1984 - "The effects of penbutolol (40 mg daily) and long-acting propranolol (160 mg daily) were assessed in 26 patients with chronic stable angina in a placebo-controlled randomised double-blind crossover study with 2-weekly treatment periods. "

01/01/1976 - "A double-blind placebo controlled study of angina pectoris with penbutolol was undertaken in parallel groups in fifty-two patients. "
01/01/1976 - "A double-blind trial of penbutolol: a new beta-receptor blocking agent in the treatment of angina pectoris."
11/01/1983 - "Haemodynamic dose-response effects of i.v. penbutolol in angina pectoris."
07/01/1981 - "Penbutolol: a preliminary review of its pharmacological properties and therapeutic efficacy in hypertension and angina pectoris."
01/01/1985 - "Double-blind comparison of prenylamine and penbutolol in patients with angina pectoris."

08/28/1985 - "Penbutolol appears to be an effective beta-blocker and one that could be used appropriately in patients with renal insufficiency."
08/28/1985 - "In this study eight hypertensive patients with renal insufficiency were studied during a three-week placebo period and then for four weeks while taking penbutolol in a dose of 40 or 80 mg daily. "
01/01/1993 - "Unchanged protein binding of penbutolol in renal insufficiency: a possible role of carbamylation."
08/28/1985 - "Effect of oral penbutolol on renal haemodynamics of hypertensive patients with renal insufficiency."
01/01/1985 - "Pharmacokinetics of penbutolol and its metabolites in renal insufficiency."

01/01/1981 - "Penbutolol, which possesses intrinsic sympathomimetic activity, may be useful in the treatment of patients in whom some other beta-blocker has failed to bring about adequate control of the blood pressure, despite marked bradycardia."
09/30/1987 - "In addition penbutolol does not cause any significant alterations in the biohumoral parameters of the patients treated and is ideal for combination with dihydralazine, reserpine and dihydrochlorotiazide in the treatment of more stubborn cases, making it possible to reduce the doses of the other drugs without causing bradycardia."
01/01/1981 - "Bradycardia occurred more frequently with atenolol than with penbutolol. "
06/01/1989 - "The lack of significant bradycardia and the low incidence of other troublesome adverse effects are potential advantages during antihypertensive therapy with penbutolol. "
07/01/1983 - "During the 6 weeks of treatment there was no change in body weight and serious side-effects were not observed, but bradycardia occurred more frequently with atenolol than with penbutolol. "