Pancreatic Pseudocyst

Cyst-like space not lined by EPITHELIUM and contained within the PANCREAS. Pancreatic pseudocysts account for most of the cystic collections in the pancreas and are often associated with chronic PANCREATITIS.

Also Known As:

Networked: 392 relevant articles (19 outcomes, 21 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Pancreatitis
2.	Cysts
3.	Necrosis
4.	Abscess
5.	Pancreatic Pseudocyst

Experts

1.	Itoi, Takao: 4 articles (02/2015 - 07/2009)
2.	Sharma, Vishal: 3 articles (06/2015 - 05/2013)
3.	Itokawa, Fumihide: 3 articles (02/2015 - 07/2009)
4.	Tsuchiya, Takayoshi: 3 articles (02/2015 - 07/2009)
5.	Moriyasu, Fuminori: 3 articles (02/2015 - 07/2009)
6.	Rana, Surinder Singh: 3 articles (02/2014 - 05/2010)
7.	Bhasin, Deepak Kumar: 3 articles (02/2014 - 05/2010)
8.	Eloubeidi, Mohamad A: 3 articles (10/2013 - 03/2012)
9.	Kowalski, Thomas: 2 articles (11/2015 - 10/2013)
10.	Gaidhane, Monica: 2 articles (11/2015 - 04/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Pancreatic Pseudocyst:

1.	Octreotide (Sandostatin)FDA LinkGeneric 06/01/1993 - "These results suggest octreotide is effective in decreasing the output from pancreatic pseudocysts drained percutaneously." 03/01/1995 - "We report the efficacy of octreotide, as an adjunct to treatment, in two children with pancreatic pseudocyst. " 12/01/2000 - "Further clinical studies are needed to assess the eventual therapeutic effect of octreotide during CJF in patients with pancreatic pseudocyst." 09/01/2011 - "This case report illustrates that use of higher octreotide acetate dosages may be a potential adjunct therapy to surgical interventions for the management of pancreatic pseudocysts in children." 09/01/2011 - "Previously reported cases demonstrated successful resolution of pancreatic pseudocysts with varying doses of intravenous and subcutaneous octreotide acetate within 23-30 days; however, with our patient's regimen, along with surgical interventions, the pseudocyst resolved within 11 days. "
2.	AmylasesFDA Link 05/01/1991 - "The aims of the study were to compare the results of endoscopic retrograde cholangiopancreatography (ERCP) and percutaneous cystopancreatography (PCP) in the detection of the communication between the pancreatic pseudocyst and the pancreatic duct, and to assess the reliability of the increased amylase concentration in the pseudocyst content as an indicator of the existence of communication between the pancreatic pseudocyst and the pancreatic duct system. " 05/01/2011 - "In the present case, the clinical background, amylase fluid levels and tomographic findings were highly suggestive of a pancreatic pseudocyst." 07/01/2008 - "A retrospective study of Chinese patients with pancreatic pseudocysts to compare the results between non-conservative and conservative treatments, and the use of serial serum amylase and imaging in monitoring treatment success. " 01/01/1994 - "Amylase, tumour markers levels in the cyst fluid and radiological findings suggested an inflammatory pancreatic pseudocyst. " 05/01/1991 - "Due to high sensitivity and specificity of pseudocyst amylase concentration for the existence of pseudocyst communication with the pancreatic duct, we conclude that guided percutaneous aspiration of the pancreatic pseudocyst with the determination of amylase concentration in the fluid can replace ERCP as a method of choice for the detection of pseudocyst communication with the pancreatic duct."
3.	Familial duodenal atresiaIBA 01/01/1994 - "In case of common occurrence of duodenal stenosis and pancreatic pseudocyst the drainage of pseudocyst was enough in 69% of cases to ensure the free gastroduodenal passage and at 31% was necessary the combined operation." 09/01/2010 - "[Endoscopic ultrasound-guided transmural cyst drainage (EUS-CD) was effective in a case of pancreatic pseudocyst with obstructive jaundice and duodenal stenosis]." 09/01/2010 - "His condition was diagnosed as acute pancreatitis with a pancreatic pseudocyst, obstructive jaundice, and duodenal stenosis. " 01/01/2000 - "The most common organ complications due to chronic pancreatitis are stenosis of the common bile duct and the pancreatic duct, duodenal stenosis, stenosis of the portal vein with portal hypertension, pancreatic pseudocysts and the development of pancreatic fistula. "
4.	Potassium Iodide (Pima)FDA Link 05/01/1975 - "A case of successful conservative surgical and obstetric management of chronic pancreatitis and pancreatic pseudocyst in a pregnant Pima Indian is presented. "
5.	OzoneIBA 11/01/2009 - "[Estimation of efficacy of the ozone-quant therapy in prophylaxis and treatment of the purulent-necrotic complications of pancreatic pseudocysts]."
6.	Bromhexine (Bisolvon)IBA 11/01/2004 - "Mediastinal pancreatic pseudocyst caused by obstruction of the pancreatic duct was eliminated by bromhexine hydrochloride."
7.	neodymium pyrocatechin disulfonate (NPD)IBA 05/01/2010 - "Pancreatic pseudocysts at atypical locations with ductal communication and partial ductal disruption that is bridged by NPD can also be effectively treated with endoscopic transpapillary NPD placement."
8.	BariumIBA 08/01/1977 - "A policy of limiting preoperative diagnostic imaging of pancreatic pseudocysts to barium studies, sonography, or computed tomography will result in failure to detect frequently associated lesions which may only be appreciated by arteriography and which radically alter both the prognosis and surgical approach. " 01/01/1995 - "After cystogastrostomy, the pancreatic pseudocyst became remarkably reduced in size, having the appearance of a shallow ulcer by barium study. " 01/01/1979 - "A pseudoaneurysm of the pancreaticoduodenal artery secondary to chronic pancreatitis was erroneously diagnosed as a pancreatic pseudocyst by abdominal plain films, barium gastrointestinal studies, and abdominal ultrasound. "
9.	Hereditary pancreatitisIBA 12/01/1978 - "Recent studies have shown a 20% spontaneous regression rate for pancreatic pseudocysts (of all etiologies), when evaluated by B-mode ultrasonography; our experience suggests that the incidence of pseudocyst formation in hereditary pancreatitis is considerably higher than previously suspected. " 11/01/2012 - "Pancreatic pseudocysts were caused by acute pancreatitis in 5 (gallstones n = 1, hereditary pancreatitis n = 1, pancreatic divisum n = 1, asparaginase induced n = 1, and idiopathic n = 1) and pancreatic trauma in 2 (motor vehicle accident n = 1, and handlebar injury n = 1). "
10.	A-factor (Streptomyces)IBA 02/01/2004 - "This study was carried out on two groups of patients with larger and smaller pancreatic pseudocysts (pancreatic pseudocysts > 10 cm versus pancreatic pseudocysts < 10 cm), and aims to establish whether the size of pancreatic pseudocysts is a factor influencing treatment outcomes. "

Therapies and Procedures

1.	Gastrostomy 01/01/1988 - "We report a case in which a naso-gastric tube, endoscopically placed through a cysto-gastrostomy, permitted the successful drainage of a large pancreatic pseudocyst without any recurrence." 07/01/1987 - "[Percutaneous pancreato-gastrostomy in the treatment of pancreatic pseudocysts. " 06/01/1984 - "[Gastrostomy drainage of pancreatic pseudocysts with additional protection during the postoperative course]." 10/22/1951 - "[Pancreatic pseudocyst; cysto-gastrostomy by the transgastric approach]." 12/01/2002 - "The laparoscopic endogastric pseudocyst gastrostomy appears to be a safe and effective minimally invasive approach for internal drainage of large retrogastric pancreatic pseudocysts and facilitates debridement of the necrotic pancreas."
2.	Catheters 09/01/2011 - "Two patients had encapsulated effusions or pancreatic pseudocysts after surgery, but were successfully cured after lavage and B ultrasound-guided percutaneous catheter drainage. " 06/01/1989 - "Aspiration or catheter drainage of pseudocyst fluid guided by ultrasonography seems a safe and effective treatment of pancreatic pseudocysts and should be considered as initial therapy. " 10/01/2010 - "The aim of the study was to present and evaluate the long-term results of percutaneous catheter drainage (PCD) in the treatment of symptomatic pancreatic pseudocysts (PPC). " 01/01/1993 - "The purpose of this study was to evaluate the results of long term percutaneous catheter drainage in the treatment of chronic pancreatic pseudocysts communicating with pancreatic ducts. " 10/01/1990 - "This study presents four cases of pancreatic pseudocyst in which percutaneous catheter drainage was performed. "
3.	Stents 10/01/2014 - "This study evaluated the relationship between stent placement and treatment outcomes in patients undergoing endoscopic transmural drainage of uncomplicated pancreatic pseudocysts. " 04/01/2012 - "Transenteric drainage of pancreatic pseudocysts and the gallbladder by using a novel, lumen-apposing, metal stent was accomplished with high technical and clinical success in this pilot observational study. " 07/01/2015 - "Endoscopic ultrasound-guided pancreatic pseudocyst cystogastrostomy using a novel self-expandable metal stent with antimigration system: A case series." 05/01/2015 - "The preferred treatment of a huge pancreatic pseudocyst is a combined endoscopic ultrasonography method using 2 double-pigtail stents and a nasocystic drain." 02/21/2015 - "Stent displacement in endoscopic pancreatic pseudocyst drainage and endoscopic management."
4.	Debridement 11/01/2003 - "Laparoscopic internal drainage of large, persistent and symptomatic pancreatic pseudocysts is safely applicable to most patients, achieves adequate drainage and facilitates debridement, and brings recognised benefits over open surgery and endoscopic approaches. " 12/01/2002 - "The laparoscopic endogastric pseudocyst gastrostomy appears to be a safe and effective minimally invasive approach for internal drainage of large retrogastric pancreatic pseudocysts and facilitates debridement of the necrotic pancreas." 05/01/2014 - "Cystogastrostomy is commonly performed for internal drainage of pancreatic pseudocysts (PP) and concomitant debridement of walled-off pancreatic necrosis (WOPN). " 09/01/2003 - "This assures meticulous hemostasis, debridement of the cyst, and wide internal drainage of the pancreatic pseudocyst. " 10/01/1994 - "Twelve with sterile necrosis unassociated with a pancreatic pseudocyst underwent surgical debridement. "
5.	Decompression 10/01/2009 - "Spontaneous decompression of pancreatic pseudocyst presenting as haematemesis." 04/01/2002 - "Laparoscopic surgery may be performed for the treatment of pancreatic pseudocyst when decompression is indicated. " 02/01/1992 - "Spontaneous gastric decompression of pancreatic pseudocyst." 02/01/1992 - "Spontaneous resolution of a pancreatic pseudocyst after a transient episode of diarrhea should suggest the mechanism of gastrointestinal decompression of the pseudocyst." 10/01/1994 - "When a pancreatic pseudocyst occurs in association with pancreatic necrosis, radiological and endoscopic decompression should not be attempted."