p-Azobenzenearsonate

A hapten capable of eliciting both antibody formation and delayed hypersensitivity when bound to aromatic amino acids, polypeptides or proteins. It is used as an immunologic research tool.

Also Known As:

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Hypersensitivity (Allergy) 05/01/1985 - "II. Delayed-type hypersensitivity induced by P-azobenzenearsonate-L-tyrosine (ABA-Tyr)." 11/01/1979 - "Anti-p-azobenzenearsonate (ABA) antibodies, coupled covalently to normal syngeneic spleen cells and then given intravenously to normal animals, were found to be potent tolerogens for delayed-type hypersensitivity (DTH) to ABA. " 04/01/1980 - "Delayed-type hypersensitivity (DTH) to p-azobenzenearsonate (ABA) can be induced in A/J mice with intravenous injection of minute amounts of anti-cross-reactive idiotypic (CRI) antibodies, providing that the animals have been pretreated 2 d earlier with low doses of cyclophosphamide (50 mg/kg). " 11/26/1965 - "Guinea pigs injected with 100 micrograms of p-azobenzenearsonate derivatives of hexa-L-tyrosine, tri-L-tyrosine, or N-acetyl-L-tyrosine amide, in complete Freund's adjuvant, developed, after 10 to 19 days, delayed-type hypersensitivity to these substances. "
2.	Autoimmune Diseases (Autoimmune Disease) 12/01/1993 - "Immunization of these mice with p-azophenylarsonate (Ars)-protein conjugates elicited the idiotypic components (IdCR) characteristic of the A/J anti-Ars response and did not interfere with the spontaneous development of the lpr-mediated autoimmune disease. "

Related Drugs and Biologics

1.	Tyrosine (L-Tyrosine)
2.	Antibodies
3.	Proteins (Proteins, Gene)
4.	Freund's Adjuvant
5.	Cyclophosphamide (Cytoxan)
6.	Amides
7.	lysyl-5-fluorotryptophyl-lysine (Tri (D))
8.	N-acetyltyrosine

Related Therapies and Procedures

1.	Intravenous Injections